| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the alprostadil-6576 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTB | actin, beta |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| APOOL | apolipoprotein O-like |
| ARMC4 | armadillo repeat containing 4 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| BBC3 | BCL2 binding component 3 |
| BTD | biotinidase |
| CAT | catalase |
| CCDC25 | coiled-coil domain containing 25 |
| CDKN2AIP | CDKN2A interacting protein |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CEP85 | centrosomal protein 85kDa |
| CES2 | carboxylesterase 2 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHMP1B | charged multivesicular body protein 1B |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CLSPN | claspin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DUSP10 | dual specificity phosphatase 10 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ENO1 | enolase 1, (alpha) |
| EPOR | erythropoietin receptor |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FANCE | Fanconi anemia, complementation group E |
| FGFR1OP | FGFR1 oncogene partner |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 |
| GCDH | glutaryl-CoA dehydrogenase |
| GLS | glutaminase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR1 | G protein-coupled receptor 1 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HDAC6 | histone deacetylase 6 |
| HLA-G | major histocompatibility complex, class I, G |
| HPCAL1 | hippocalcin-like 1 |
| HSF1 | heat shock transcription factor 1 |
| IFT140 | intraflagellar transport 140 |
| INO80B | INO80 complex subunit B |
| IREB2 | iron-responsive element binding protein 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KIAA0355 | KIAA0355 |
| KLHL24 | kelch-like family member 24 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LHX2 | LIM homeobox 2 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) |
| MAP9 | microtubule-associated protein 9 |
| MED16 | mediator complex subunit 16 |
| MTCL1 | microtubule crosslinking factor 1 |
| MXD4 | MAX dimerization protein 4 |
| NFYC | nuclear transcription factor Y, gamma |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PEX19 | peroxisomal biogenesis factor 19 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PODNL1 | podocan-like 1 |
| PPIF | peptidylprolyl isomerase F |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PRMT2IP | PRMT2 interacting protein |
| PTBP3 | polypyrimidine tract binding protein 3 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| REEP1 | receptor accessory protein 1 |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RGS12 | regulator of G-protein signaling 12 |
| RIOK3 | RIO kinase 3 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRM1 | ribonucleotide reductase M1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A11 | S100 calcium binding protein A11 |
| SIRT2 | sirtuin 2 |
| SIRT3 | sirtuin 3 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SYNJ2 | synaptojanin 2 |
| SYNRG | synergin, gamma |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TBL1X | transducin (beta)-like 1X-linked |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TLN1 | talin 1 |
| TMEM230 | transmembrane protein 230 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRRAP | transformation/transcription domain-associated protein |
| TTBK2 | tau tubulin kinase 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBA3C | tubulin, alpha 3c |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CCDC69 | coiled-coil domain containing 69 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CMTR1 | cap methyltransferase 1 |
| CORT | cortistatin |
| CRBN | cereblon |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| EMID1 | EMI domain containing 1 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM46C | family with sequence similarity 46, member C |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO2 | F-box protein 2 |
| FBXO31 | F-box protein 31 |
| FGL1 | fibrinogen-like 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| HOMER2 | homer scaffolding protein 2 |
| HOXA4 | homeobox A4 |
| IFT54 | intraflagellar transport 54 |
| IL4R | interleukin 4 receptor |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KIAA1324 | KIAA1324 |
| KIFAP3 | kinesin-associated protein 3 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT31 | keratin 31, type I |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMNB1 | lamin B1 |
| LONP2 | lon peptidase 2, peroxisomal |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MCOLN1 | mucolipin 1 |
| MMRN2 | multimerin 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLTP | phospholipid transfer protein |
| PRR4 | proline rich 4 (lacrimal) |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFPL3 | ret finger protein-like 3 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RLF | rearranged L-myc fusion |
| RPGR | retinitis pigmentosa GTPase regulator |
| SAA3P | serum amyloid A3 pseudogene |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMA4 | glucuronidase, beta pseudogene |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBX19 | T-box 19 |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| VAX2 | ventral anterior homeobox 2 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF205 | zinc finger protein 205 |
| ZNF41 | zinc finger protein 41 |
| ZNF516 | zinc finger protein 516 |
| ZNF551 | zinc finger protein 551 |
| ZNF573 | zinc finger protein 573 |
| ZNF701 | zinc finger protein 701 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
