| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the alprostadil-7358 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ARTN | artemin |
| ATXN2L | ataxin 2-like |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BIN1 | bridging integrator 1 |
| BMP5 | bone morphogenetic protein 5 |
| C19ORF26 | chromosome 19 open reading frame 26 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC64 | coiled-coil domain containing 64 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DENND5B | DENN/MADD domain containing 5B |
| DFNB31 | deafness, autosomal recessive 31 |
| DOC2A | double C2-like domains, alpha |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFCAB11 | EF-hand calcium binding domain 11 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPOR | erythropoietin receptor |
| FAM169A | family with sequence similarity 169, member A |
| FRK | fyn-related Src family tyrosine kinase |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAS6 | growth arrest-specific 6 |
| GK | glycerol kinase |
| GPR137 | G protein-coupled receptor 137 |
| HBB | hemoglobin, beta |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HLA-C | major histocompatibility complex, class I, C |
| HNMT | histamine N-methyltransferase |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IRS2 | insulin receptor substrate 2 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| JAK3 | Janus kinase 3 |
| KIF25 | kinesin family member 25 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LMAN1 | lectin, mannose-binding, 1 |
| LMBR1L | limb development membrane protein 1-like |
| LRRC14 | leucine rich repeat containing 14 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAP1S | microtubule-associated protein 1S |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAPT | microtubule-associated protein tau |
| MITF | microphthalmia-associated transcription factor |
| MMP11 | matrix metallopeptidase 11 |
| MTA1 | metastasis associated 1 |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NLRX1 | NLR family member X1 |
| NPTX1 | neuronal pentraxin I |
| NUP50 | nucleoporin 50kDa |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PBRM1 | polybromo 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLXNA3 | plexin A3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PORCN | porcupine homolog (Drosophila) |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PXN | paxillin |
| RBM26 | RNA binding motif protein 26 |
| RECQL5 | RecQ protein-like 5 |
| RGS12 | regulator of G-protein signaling 12 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RSU1 | Ras suppressor protein 1 |
| S100A9 | S100 calcium binding protein A9 |
| SCRN3 | secernin 3 |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIX2 | SIX homeobox 2 |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM80 | transmembrane protein 80 |
| TPSG1 | tryptase gamma 1 |
| UBXN6 | UBX domain protein 6 |
| VDAC3 | voltage-dependent anion channel 3 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF783 | zinc finger family member 783 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADCY7 | adenylate cyclase 7 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC85C | coiled-coil domain containing 85C |
| CDON | cell adhesion associated, oncogene regulated |
| CENPO | centromere protein O |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEAF1 | DEAF1 transcription factor |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DMTN | dematin actin binding protein |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EMID1 | EMI domain containing 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXN2 | forkhead box N2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPR27 | G protein-coupled receptor 27 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3B | histone cluster 1, H3b |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IRF1 | interferon regulatory factor 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| LIN7A | lin-7 homolog A (C. elegans) |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCOLN3 | mucolipin 3 |
| MOSPD3 | motile sperm domain containing 3 |
| MUC3B | mucin 3B, cell surface associated |
| NEK11 | NIMA-related kinase 11 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLAT | plasminogen activator, tissue |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POM121 | POM121 transmembrane nucleoporin |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANBP17 | RAN binding protein 17 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF121 | ring finger protein 121 |
| RNF39 | ring finger protein 39 |
| SDC3 | syndecan 3 |
| SETD1A | SET domain containing 1A |
| SH2D4A | SH2 domain containing 4A |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIX1 | SIX homeobox 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SP1 | Sp1 transcription factor |
| SPATA2L | spermatogenesis associated 2-like |
| SREK1IP1 | SREK1-interacting protein 1 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SYNC | syncoilin, intermediate filament protein |
| TAGLN | transgelin |
| TAOK1 | TAO kinase 1 |
| TCTN2 | tectonic family member 2 |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM115 | transmembrane protein 115 |
| TMEM120B | transmembrane protein 120B |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAIP | TRAF interacting protein |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VASH1 | vasohibin 1 |
| WDR91 | WD repeat domain 91 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF8 | zinc finger protein 8 |
