alsterpaullone-7051 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the alsterpaullone-7051 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ABHD14A abhydrolase domain containing 14A
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTC1 actin, alpha, cardiac muscle 1
AEN apoptosis enhancing nuclease
AK2 adenylate kinase 2
ALLC allantoicase
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
BTBD18 BTB (POZ) domain containing 18
BTF3P12 basic transcription factor 3 pseudogene 12
BTG2 BTG family, member 2
C9ORF9 chromosome 9 open reading frame 9
CA12 carbonic anhydrase XII
CACYBP calcyclin binding protein
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLEC4M C-type lectin domain family 4, member M
COL21A1 collagen, type XXI, alpha 1
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DUSP8 dual specificity phosphatase 8
EGR1 early growth response 1
EHD2 EH-domain containing 2
ELL2 elongation factor, RNA polymerase II, 2
FGF18 fibroblast growth factor 18
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
GAMT guanidinoacetate N-methyltransferase
GPR157 G protein-coupled receptor 157
GTPBP4 GTP binding protein 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HP haptoglobin
HPX hemopexin
IDI2-AS1 IDI2 antisense RNA 1
IFITM1 interferon induced transmembrane protein 1
ISG20 interferon stimulated exonuclease gene 20kDa
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0408 KIAA0408
KLF6 Kruppel-like factor 6
KREMEN2 kringle containing transmembrane protein 2
LAMP1 lysosomal-associated membrane protein 1
LAT2 linker for activation of T cells family, member 2
LIF leukemia inhibitory factor
LIMCH1 LIM and calponin homology domains 1
LINC00341 long intergenic non-protein coding RNA 341
LOC157562 uncharacterized LOC157562
LONP2 lon peptidase 2, peroxisomal
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAP4 microtubule-associated protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFSD11 major facilitator superfamily domain containing 11
MIA melanoma inhibitory activity
MOBP myelin-associated oligodendrocyte basic protein
NHLH2 nescient helix loop helix 2
NOV nephroblastoma overexpressed
NPFF neuropeptide FF-amide peptide precursor
NPM3 nucleophosmin/nucleoplasmin 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRGN neurogranin (protein kinase C substrate, RC3)
NSUN6 NOP2/Sun domain family, member 6
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARD6B par-6 family cell polarity regulator beta
PDE4C phosphodiesterase 4C, cAMP-specific
PEX26 peroxisomal biogenesis factor 26
PPT2 palmitoyl-protein thioesterase 2
PRKCA protein kinase C, alpha
PRLH prolactin releasing hormone
PVT1 Pvt1 oncogene (non-protein coding)
PYGM phosphorylase, glycogen, muscle
RAB11B RAB11B, member RAS oncogene family
RANBP1 RAN binding protein 1
RARA retinoic acid receptor, alpha
RFPL3S RFPL3 antisense
RPL10L ribosomal protein L10-like
RPS28 ribosomal protein S28
S100A2 S100 calcium binding protein A2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCAND2P SCAN domain containing 2 pseudogene
SCG5 secretogranin V
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFPQ splicing factor proline/glutamine-rich
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SMA4 glucuronidase, beta pseudogene
SPATS2L spermatogenesis associated, serine-rich 2-like
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STAG3 stromal antigen 3
TMEM144 transmembrane protein 144
TSPAN32 tetraspanin 32
TUBA3C tubulin, alpha 3c
UCN urocortin
USP36 ubiquitin specific peptidase 36
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
AMD1 adenosylmethionine decarboxylase 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD49 ankyrin repeat domain 49
ARHGAP12 Rho GTPase activating protein 12
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
BAMBI BMP and activin membrane-bound inhibitor
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTG1 B-cell translocation gene 1, anti-proliferative
BYSL bystin-like
C14ORF169 chromosome 14 open reading frame 169
CASP8AP2 caspase 8 associated protein 2
CCNL1 cyclin L1
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLK4 CDC-like kinase 4
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CSRNP2 cysteine-serine-rich nuclear protein 2
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DOLK dolichol kinase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FADD Fas (TNFRSF6)-associated via death domain
FBXL14 F-box and leucine-rich repeat protein 14
FIP1L1 factor interacting with PAPOLA and CPSF1
GEMIN4 gem (nuclear organelle) associated protein 4
GIN1 gypsy retrotransposon integrase 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GUSBP3 glucuronidase, beta pseudogene 3
HAUS3 HAUS augmin-like complex, subunit 3
HILPDA hypoxia inducible lipid droplet-associated
HJURP Holliday junction recognition protein
HOXC6 homeobox C6
IFRD1 interferon-related developmental regulator 1
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
ING3 inhibitor of growth family, member 3
IRS1 insulin receptor substrate 1
KBTBD2 kelch repeat and BTB (POZ) domain containing 2
KDM3A lysine (K)-specific demethylase 3A
KIN Kin17 DNA and RNA binding protein
LEMD3 LEM domain containing 3
LOC100272216 uncharacterized LOC100272216
LRIF1 ligand dependent nuclear receptor interacting factor 1
MED17 mediator complex subunit 17
MED23 mediator complex subunit 23
METTL18 methyltransferase like 18
MFSD5 major facilitator superfamily domain containing 5
MGA MGA, MAX dimerization protein
NCAPH non-SMC condensin I complex, subunit H
NCK1 NCK adaptor protein 1
NDC80 NDC80 kinetochore complex component
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae)
OSR2 odd-skipped related transciption factor 2
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRR15L proline rich 15-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RANBP6 RAN binding protein 6
RBM7 RNA binding motif protein 7
RCOR1 REST corepressor 1
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RMI1 RecQ mediated genome instability 1
RNF103 ring finger protein 103
RPP25 ribonuclease P/MRP 25kDa subunit
RPP38 ribonuclease P/MRP 38kDa subunit
RSBN1 round spermatid basic protein 1
S100PBP S100P binding protein
SAP130 Sin3A-associated protein, 130kDa
SCAF8 SR-related CTD-associated factor 8
SIRT1 sirtuin 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC38A2 solute carrier family 38, member 2
SPATA2L spermatogenesis associated 2-like
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa
TBPL1 TBP-like 1
THAP11 THAP domain containing 11
TMEM185B transmembrane protein 185B
TRIM32 tripartite motif containing 32
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
TTK TTK protein kinase
WDR82 WD repeat domain 82
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBED5 zinc finger, BED-type containing 5
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF217 zinc finger protein 217
ZNF232 zinc finger protein 232
ZNF274 zinc finger protein 274
ZNF443 zinc finger protein 443
ZNF84 zinc finger protein 84
ZZZ3 zinc finger, ZZ-type containing 3