altered susceptibility to atherosclerosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description a change in the likelihood that an organism will develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries (Mammalian Phenotype Ontology, MP_0005340)
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16 gene mutations causing the altered susceptibility to atherosclerosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
CSF1 colony stimulating factor 1 (macrophage)
HPS1 Hermansky-Pudlak syndrome 1
HPS4 Hermansky-Pudlak syndrome 4
HPS5 Hermansky-Pudlak syndrome 5
KLF15 Kruppel-like factor 15
LDLR low density lipoprotein receptor
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PLA2G15 phospholipase A2, group XV
PON1 paraoxonase 1
PON2 paraoxonase 2
RORA RAR-related orphan receptor A
SCARB1 scavenger receptor class B, member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SPP1 secreted phosphoprotein 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4