| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the altretamine-6467 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| BGN | biglycan |
| BMP4 | bone morphogenetic protein 4 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C1QB | complement component 1, q subcomponent, B chain |
| CACTIN | cactin, spliceosome C complex subunit |
| CAMKV | CaM kinase-like vesicle-associated |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCR7 | chemokine (C-C motif) receptor 7 |
| CD44 | CD44 molecule (Indian blood group) |
| CD52 | CD52 molecule |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYTH1 | cytohesin 1 |
| DES | desmin |
| DESI2 | desumoylating isopeptidase 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLX4 | distal-less homeobox 4 |
| DPYS | dihydropyrimidinase |
| DRD2 | dopamine receptor D2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLJ42627 | uncharacterized LOC645644 |
| FMO5 | flavin containing monooxygenase 5 |
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
| GAS6 | growth arrest-specific 6 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPX5 | glutathione peroxidase 5 |
| HAL | histidine ammonia-lyase |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HNF1B | HNF1 homeobox B |
| HOXA4 | homeobox A4 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF5 | interferon regulatory factor 5 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF1C | kinesin family member 1C |
| KIF5A | kinesin family member 5A |
| KLHL9 | kelch-like family member 9 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT75 | keratin 75, type II |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC75B | leucine rich repeat containing 75B |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MYO1B | myosin IB |
| NF2 | neurofibromin 2 (merlin) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OCM2 | oncomodulin 2 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU2F2 | POU class 2 homeobox 2 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RNF122 | ring finger protein 122 |
| SCRT1 | scratch family zinc finger 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPAG8 | sperm associated antigen 8 |
| SQLE | squalene epoxidase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK24 | serine/threonine kinase 24 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TGM2 | transglutaminase 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM8B | transmembrane protein 8B |
| TOP3B | topoisomerase (DNA) III beta |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF362 | zinc finger protein 362 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC6 | armadillo repeat containing 6 |
| ASPN | asporin |
| ATXN2 | ataxin 2 |
| C5AR2 | complement component 5a receptor 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC9 | coiled-coil domain containing 9 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CEL | carboxyl ester lipase |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN17 | claudin 17 |
| CLIC2 | chloride intracellular channel 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FOSL1 | FOS-like antigen 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPC3 | glypican 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IMPACT | impact RWD domain protein |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA1456 | KIAA1456 |
| KLHL26 | kelch-like family member 26 |
| KLHL36 | kelch-like family member 36 |
| KLK5 | kallikrein-related peptidase 5 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL3 | lysyl oxidase-like 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC61 | leucine rich repeat containing 61 |
| LYRM9 | LYR motif containing 9 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK12 | mitogen-activated protein kinase 12 |
| MYO1E | myosin IE |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NELL2 | NEL-like 2 (chicken) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARPBP | PARP1 binding protein |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLD2 | phospholipase D2 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRDM14 | PR domain containing 14 |
| PRSS50 | protease, serine, 50 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF25 | ring finger protein 25 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCHIP1 | schwannomin interacting protein 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STRA6 | stimulated by retinoic acid 6 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TMC5 | transmembrane channel-like 5 |
| TMEM254 | transmembrane protein 254 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRAIP | TRAF interacting protein |
| TSPAN1 | tetraspanin 1 |
| VASH1 | vasohibin 1 |
| WDR62 | WD repeat domain 62 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF16 | zinc finger protein 16 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF219 | zinc finger protein 219 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF408 | zinc finger protein 408 |
| ZNF586 | zinc finger protein 586 |
| ZNF74 | zinc finger protein 74 |
| ZNF821 | zinc finger protein 821 |
