alveolitis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An interstitial lung disease involving inflammation of alveoli and smallest airways (bronchioles) of the lung caused by an allergic reaction to inhaled organic dusts containing microorganisms or proteins, and chemicals. Symptoms include chills, cough, fever, malaise, shortness of breath, loss of appetite and weight loss. (Human Disease Ontology, DOID_841)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010922
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Genes

5 gene mutations causing the alveolitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FBN1 fibrillin 1
HPS1 Hermansky-Pudlak syndrome 1
LYST lysosomal trafficking regulator
SPTA1 spectrin, alpha, erythrocytic 1
WWTR1 WW domain containing transcription regulator 1