alverine-1426 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the alverine-1426 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ANKRD12 ankyrin repeat domain 12
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOC1 apolipoprotein C-I
ARHGAP10 Rho GTPase activating protein 10
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARID5A AT rich interactive domain 5A (MRF1-like)
ARRB2 arrestin, beta 2
ATAD2B ATPase family, AAA domain containing 2B
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAX BCL2-associated X protein
BUB3 BUB3 mitotic checkpoint protein
C1QTNF1 C1q and tumor necrosis factor related protein 1
C5ORF45 chromosome 5 open reading frame 45
CAV3 caveolin 3
CBY1 chibby homolog 1 (Drosophila)
CCDC64 coiled-coil domain containing 64
CCHCR1 coiled-coil alpha-helical rod protein 1
CD47 CD47 molecule
CIITA class II, major histocompatibility complex, transactivator
CLCN6 chloride channel, voltage-sensitive 6
CRYAB crystallin, alpha B
DAAM2 dishevelled associated activator of morphogenesis 2
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DLG1 discs, large homolog 1 (Drosophila)
DUSP3 dual specificity phosphatase 3
DUSP8 dual specificity phosphatase 8
E2F1 E2F transcription factor 1
F11R F11 receptor
FAIM2 Fas apoptotic inhibitory molecule 2
FAM208A family with sequence similarity 208, member A
FBXO42 F-box protein 42
FMO4 flavin containing monooxygenase 4
GJC2 gap junction protein, gamma 2, 47kDa
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSK3A glycogen synthase kinase 3 alpha
IDUA iduronidase, alpha-L-
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL27RA interleukin 27 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
KIFC1 kinesin family member C1
KRT2 keratin 2, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIMD1 LIM domains containing 1
LPPR3 lipid phosphate phosphatase-related protein type 3
LY6E lymphocyte antigen 6 complex, locus E
MAML3 mastermind-like 3 (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MDC1 mediator of DNA-damage checkpoint 1
MED18 mediator complex subunit 18
MEF2D myocyte enhancer factor 2D
MGC2889 uncharacterized protein MGC2889
MKS1 Meckel syndrome, type 1
MT3 metallothionein 3
N4BP1 NEDD4 binding protein 1
NHEJ1 nonhomologous end-joining factor 1
NOTCH2 notch 2
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEC plectin
PLEK2 pleckstrin 2
PLLP plasmolipin
POLG polymerase (DNA directed), gamma
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP5C protein phosphatase 5, catalytic subunit
PQLC2 PQ loop repeat containing 2
PRDM14 PR domain containing 14
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
QTRT1 queuine tRNA-ribosyltransferase 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RUNDC3A RUN domain containing 3A
SASH1 SAM and SH3 domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SP140L SP140 nuclear body protein-like
SPPL2B signal peptide peptidase like 2B
SPRY4 sprouty homolog 4 (Drosophila)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STAT4 signal transducer and activator of transcription 4
STK16 serine/threonine kinase 16
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEAD4 TEA domain family member 4
TRA T cell receptor alpha locus
TRAK2 trafficking protein, kinesin binding 2
TREX1 three prime repair exonuclease 1
TTC26 tetratricopeptide repeat domain 26
TUBB3 tubulin, beta 3 class III
VARS valyl-tRNA synthetase
ZNF473 zinc finger protein 473
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACO1 aconitase 1, soluble
ACSL4 acyl-CoA synthetase long-chain family member 4
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARGLU1 arginine and glutamate rich 1
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASB8 ankyrin repeat and SOCS box containing 8
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATXN2 ataxin 2
AZI2 5-azacytidine induced 2
BCL10 B-cell CLL/lymphoma 10
BCL7C B-cell CLL/lymphoma 7C
BEX1 brain expressed, X-linked 1
BRIX1 BRX1, biogenesis of ribosomes
C1D C1D nuclear receptor corepressor
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C5ORF28 chromosome 5 open reading frame 28
C5ORF30 chromosome 5 open reading frame 30
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC91 coiled-coil domain containing 91
CD302 CD302 molecule
CDK8 cyclin-dependent kinase 8
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLDN15 claudin 15
CRY1 cryptochrome circadian clock 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DERL2 derlin 2
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIXDC1 DIX domain containing 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DMXL1 Dmx-like 1
DPP3 dipeptidyl-peptidase 3
DTWD1 DTW domain containing 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERBB2IP erbb2 interacting protein
FAF1 Fas (TNFRSF6) associated factor 1
FANCF Fanconi anemia, complementation group F
FUBP3 far upstream element (FUSE) binding protein 3
GJD2 gap junction protein, delta 2, 36kDa
GMPPB GDP-mannose pyrophosphorylase B
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IL10RB interleukin 10 receptor, beta
INPPL1 inositol polyphosphate phosphatase-like 1
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGT1 magnesium transporter 1
MAP1S microtubule-associated protein 1S
MGAM maltase-glucoamylase
MLPH melanophilin
MNS1 meiosis-specific nuclear structural 1
MORC3 MORC family CW-type zinc finger 3
MTERF3 mitochondrial transcription termination factor 3
MTMR6 myotubularin related protein 6
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NEMF nuclear export mediator factor
NIP7 NIP7, nucleolar pre-rRNA processing protein
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAK1IP1 PAK1 interacting protein 1
PAQR3 progestin and adipoQ receptor family member III
PARG poly (ADP-ribose) glycohydrolase
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCD1 phospholipase C, delta 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRPF39 pre-mRNA processing factor 39
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RBM7 RNA binding motif protein 7
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RPS14P3 ribosomal protein S14 pseudogene 3
RUVBL1 RuvB-like AAA ATPase 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SDHAF3 succinate dehydrogenase complex assembly factor 3
SH3GL1 SH3-domain GRB2-like 1
SLC25A44 solute carrier family 25, member 44
SLMO2 slowmo homolog 2 (Drosophila)
SNX15 sorting nexin 15
SRBD1 S1 RNA binding domain 1
STIM1 stromal interaction molecule 1
SUN2 Sad1 and UNC84 domain containing 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM123 transmembrane protein 123
TMEM127 transmembrane protein 127
TMEM38B transmembrane protein 38B
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPYL1 TSPY-like 1
TTBK2 tau tubulin kinase 2
TULP4 tubby like protein 4
UBXN6 UBX domain protein 6
UNG uracil-DNA glycosylase
XBP1 X-box binding protein 1
ZBTB48 zinc finger and BTB domain containing 48
ZEB2 zinc finger E-box binding homeobox 2
ZNF140 zinc finger protein 140
ZNF267 zinc finger protein 267