| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the alverine-6345 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCS | copper chaperone for superoxide dismutase |
| CD8B | CD8b molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| COL1A1 | collagen, type I, alpha 1 |
| CPNE7 | copine VII |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| DCTN1 | dynactin 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DMPK | dystrophia myotonica-protein kinase |
| DNM3 | dynamin 3 |
| DST | dystonin |
| EFNB3 | ephrin-B3 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EXOSC2 | exosome component 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FH | fumarate hydratase |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FOLH1 | folate hydrolase (prostate-specific membrane antigen) 1 |
| FOSL2 | FOS-like antigen 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GAS8 | growth arrest-specific 8 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR17 | G protein-coupled receptor 17 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HNF1B | HNF1 homeobox B |
| HOXC10 | homeobox C10 |
| HPN | hepsin |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL5RA | interleukin 5 receptor, alpha |
| INO80B | INO80 complex subunit B |
| IQCK | IQ motif containing K |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIF1A | kinesin family member 1A |
| KLHL20 | kelch-like family member 20 |
| LDB1 | LIM domain binding 1 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MFN2 | mitofusin 2 |
| MID1 | midline 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MST1 | macrophage stimulating 1 |
| MTAP | methylthioadenosine phosphorylase |
| NAAA | N-acylethanolamine acid amidase |
| NDE1 | nudE neurodevelopment protein 1 |
| NF1 | neurofibromin 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCGF3 | polycomb group ring finger 3 |
| PDCD2 | programmed cell death 2 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLCL2 | phospholipase C-like 2 |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRAMEF11 | PRAME family member 11 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDX2 | peroxiredoxin 2 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| RAB36 | RAB36, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RNF122 | ring finger protein 122 |
| RPL10 | ribosomal protein L10 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SAFB | scaffold attachment factor B |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRT6 | sirtuin 6 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| STK24 | serine/threonine kinase 24 |
| TBC1D30 | TBC1 domain family, member 30 |
| TGFB2 | transforming growth factor, beta 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TSFM | Ts translation elongation factor, mitochondrial |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBE4B | ubiquitination factor E4B |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| ZFP30 | ZFP30 zinc finger protein |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD8 | abhydrolase domain containing 8 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATP13A2 | ATPase type 13A2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CCDC85C | coiled-coil domain containing 85C |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CUL9 | cullin 9 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGF | epidermal growth factor |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EVPL | envoplakin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FCHO1 | FCH domain only 1 |
| FOXA1 | forkhead box A1 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC7 | histone deacetylase 7 |
| HOXC8 | homeobox C8 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0754 | KIAA0754 |
| KIF13B | kinesin family member 13B |
| LSR | lipolysis stimulated lipoprotein receptor |
| MAGEH1 | melanoma antigen family H1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN1 | mucolipin 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MVP | major vault protein |
| MYOZ3 | myozenin 3 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| OLFML2A | olfactomedin-like 2A |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PCBP4 | poly(rC) binding protein 4 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDE12 | phosphodiesterase 12 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLA2G15 | phospholipase A2, group XV |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRSS16 | protease, serine, 16 (thymus) |
| PTGES2 | prostaglandin E synthase 2 |
| PTGFR | prostaglandin F receptor (FP) |
| RBM38 | RNA binding motif protein 38 |
| RNF146 | ring finger protein 146 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| ROGDI | rogdi homolog (Drosophila) |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| STX1A | syntaxin 1A (brain) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TESK2 | testis-specific kinase 2 |
| THBS3 | thrombospondin 3 |
| TIGD6 | tigger transposable element derived 6 |
| TLN1 | talin 1 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM21 | tripartite motif containing 21 |
| TRIM9 | tripartite motif containing 9 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN15 | tetraspanin 15 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TUBA3C | tubulin, alpha 3c |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF408 | zinc finger protein 408 |
| ZNF528 | zinc finger protein 528 |
| ZNF571 | zinc finger protein 571 |
| ZNF592 | zinc finger protein 592 |
| ZNF675 | zinc finger protein 675 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |