| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the alvespimycin-1051 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARMC8 | armadillo repeat containing 8 |
| ATXN1 | ataxin 1 |
| AZI2 | 5-azacytidine induced 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHPF2 | chondroitin polymerizing factor 2 |
| CLK1 | CDC-like kinase 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EFHD1 | EF-hand domain family, member D1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GRB10 | growth factor receptor-bound protein 10 |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| INO80B | INO80 complex subunit B |
| KLK6 | kallikrein-related peptidase 6 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| MAP1B | microtubule-associated protein 1B |
| MAP4 | microtubule-associated protein 4 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MED1 | mediator complex subunit 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MON1B | MON1 secretory trafficking family member B |
| MRPL18 | mitochondrial ribosomal protein L18 |
| MSX1 | msh homeobox 1 |
| NDRG4 | NDRG family member 4 |
| OPA1 | optic atrophy 1 (autosomal dominant) |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PIAS1 | protein inhibitor of activated STAT, 1 |
| PPME1 | protein phosphatase methylesterase 1 |
| PRKD2 | protein kinase D2 |
| PRNP | prion protein |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RBM23 | RNA binding motif protein 23 |
| RSRC2 | arginine/serine-rich coiled-coil 2 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLBP | stem-loop binding protein |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STIP1 | stress-induced phosphoprotein 1 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYNM | synemin, intermediate filament protein |
| TES | testin LIM domain protein |
| TSC22D1 | TSC22 domain family, member 1 |
| TSPYL4 | TSPY-like 4 |
| TXNIP | thioredoxin interacting protein |
| UBB | ubiquitin B |
| UBC | ubiquitin C |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UNKL | unkempt family zinc finger-like |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF14 | zinc finger protein 14 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF43 | zinc finger protein 43 |
| ZNF430 | zinc finger protein 430 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AFG3L2 | AFG3-like AAA ATPase 2 |
| AIDA | axin interactor, dorsalization associated |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANKRD36B | ankyrin repeat domain 36B |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APIP | APAF1 interacting protein |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARPC3 | actin related protein 2/3 complex, subunit 3, 21kDa |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BYSL | bystin-like |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C1ORF174 | chromosome 1 open reading frame 174 |
| CAMLG | calcium modulating ligand |
| CBR3 | carbonyl reductase 3 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDC7 | cell division cycle 7 |
| CRIPT | cysteine-rich PDZ-binding protein |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTPS1 | CTP synthase 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DTWD1 | DTW domain containing 1 |
| DTYMK | deoxythymidylate kinase (thymidylate kinase) |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ESRP2 | epithelial splicing regulatory protein 2 |
| ESYT1 | extended synaptotagmin-like protein 1 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FNBP1L | formin binding protein 1-like |
| FOXC1 | forkhead box C1 |
| GAA | glucosidase, alpha; acid |
| GAR1 | GAR1 ribonucleoprotein |
| GLMN | glomulin, FKBP associated protein |
| H1FX | H1 histone family, member X |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HELZ | helicase with zinc finger |
| HIRA | histone cell cycle regulator |
| HLTF | helicase-like transcription factor |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IRX5 | iroquois homeobox 5 |
| KIAA0196 | KIAA0196 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MCM10 | minichromosome maintenance complex component 10 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRGBP | MRG/MORF4L binding protein |
| MTX2 | metaxin 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NABP2 | nucleic acid binding protein 2 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NPY1R | neuropeptide Y receptor Y1 |
| OSBPL9 | oxysterol binding protein-like 9 |
| PALB2 | partner and localizer of BRCA2 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PPCS | phosphopantothenoylcysteine synthetase |
| PRR15L | proline rich 15-like |
| PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RARS | arginyl-tRNA synthetase |
| RBM14 | RNA binding motif protein 14 |
| RGS16 | regulator of G-protein signaling 16 |
| RPS21 | ribosomal protein S21 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SRSF4 | serine/arginine-rich splicing factor 4 |
| SRSF6 | serine/arginine-rich splicing factor 6 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) |
| SYTL2 | synaptotagmin-like 2 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TBC1D31 | TBC1 domain family, member 31 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TMEM109 | transmembrane protein 109 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TTC31 | tetratricopeptide repeat domain 31 |
| WDR46 | WD repeat domain 46 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF721 | zinc finger protein 721 |
