| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the alvespimycin-1154 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALOX5 | arachidonate 5-lipoxygenase |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| AZI2 | 5-azacytidine induced 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTBD7 | BTB (POZ) domain containing 7 |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CAST | calpastatin |
| CD82 | CD82 molecule |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRY2 | cryptochrome circadian clock 2 |
| CRYZ | crystallin, zeta (quinone reductase) |
| DAPK1 | death-associated protein kinase 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTNA | dystrobrevin, alpha |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EXOC7 | exocyst complex component 7 |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLOT1 | flotillin 1 |
| FZD7 | frizzled class receptor 7 |
| GLIPR1 | GLI pathogenesis-related 1 |
| HFE | hemochromatosis |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IDS | iduronate 2-sulfatase |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0753 | KIAA0753 |
| KLF6 | Kruppel-like factor 6 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LY96 | lymphocyte antigen 96 |
| MANSC1 | MANSC domain containing 1 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOB3B | MOB kinase activator 3B |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NCOA2 | nuclear receptor coactivator 2 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHACTR2 | phosphatase and actin regulator 2 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPID | peptidylprolyl isomerase D |
| PRMT2 | protein arginine methyltransferase 2 |
| PRNP | prion protein |
| PRR4 | proline rich 4 (lacrimal) |
| PYGB | phosphorylase, glycogen; brain |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF25 | ring finger protein 25 |
| RPL35A | ribosomal protein L35a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SKI | SKI proto-oncogene |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STIP1 | stress-induced phosphoprotein 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TBC1D5 | TBC1 domain family, member 5 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TGFB1 | transforming growth factor, beta 1 |
| THBS1 | thrombospondin 1 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBB | ubiquitin B |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADRB2 | adrenoceptor beta 2, surface |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APH1B | APH1B gamma secretase subunit |
| APOBR | apolipoprotein B receptor |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| B3GNT1 | |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BLVRB | biliverdin reductase B |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPN15 | calpain 15 |
| CD1D | CD1d molecule |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CFL1 | cofilin 1 (non-muscle) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLEC16A | C-type lectin domain family 16, member A |
| CNPY3 | canopy FGF signaling regulator 3 |
| CORO7 | coronin 7 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| DENND2D | DENN/MADD domain containing 2D |
| DENND4C | DENN/MADD domain containing 4C |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| E4F1 | E4F transcription factor 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFHD2 | EF-hand domain family, member D2 |
| ENDOG | endonuclease G |
| ERCC2 | excision repair cross-complementation group 2 |
| EXD2 | exonuclease 3'-5' domain containing 2 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FOXO3 | forkhead box O3 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HDAC5 | histone deacetylase 5 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| JMJD4 | jumonji domain containing 4 |
| KLHL21 | kelch-like family member 21 |
| LAS1L | LAS1-like (S. cerevisiae) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRGBP | MRG/MORF4L binding protein |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MRPS34 | mitochondrial ribosomal protein S34 |
| MYL5 | myosin, light chain 5, regulatory |
| NFE2 | nuclear factor, erythroid 2 |
| NLRX1 | NLR family member X1 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PMM2 | phosphomannomutase 2 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRKCZ | protein kinase C, zeta |
| PTCD1 | pentatricopeptide repeat domain 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RECQL4 | RecQ protein-like 4 |
| RNF122 | ring finger protein 122 |
| RNF220 | ring finger protein 220 |
| RNF31 | ring finger protein 31 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2B2 | SH2B adaptor protein 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SURF2 | surfeit 2 |
| TAOK1 | TAO kinase 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TERT | telomerase reverse transcriptase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNRC6B | trinucleotide repeat containing 6B |
| TOR4A | torsin family 4, member A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRIM45 | tripartite motif containing 45 |
| TRIM58 | tripartite motif containing 58 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| VANGL1 | VANGL planar cell polarity protein 1 |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF232 | zinc finger protein 232 |
| ZNF580 | zinc finger protein 580 |
| ZNF629 | zinc finger protein 629 |
