| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alvespimycin-1213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AIM2 | absent in melanoma 2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| BAG3 | BCL2-associated athanogene 3 |
| BMP15 | bone morphogenetic protein 15 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CACYBP | calcyclin binding protein |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCNT2 | cyclin T2 |
| CD53 | CD53 molecule |
| CD58 | CD58 molecule |
| CHN2 | chimerin 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLU | clusterin |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTGF | connective tissue growth factor |
| CYTH1 | cytohesin 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DOCK10 | dedicator of cytokinesis 10 |
| DUSP1 | dual specificity phosphatase 1 |
| ECE1 | endothelin converting enzyme 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ESRRG | estrogen-related receptor gamma |
| FAM204A | family with sequence similarity 204, member A |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FOXC1 | forkhead box C1 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL7R | interleukin 7 receptor |
| ING4 | inhibitor of growth family, member 4 |
| INO80B | INO80 complex subunit B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNJ8 | potassium channel, inwardly rectifying subfamily J, member 8 |
| KIF1A | kinesin family member 1A |
| KLHL36 | kelch-like family member 36 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYZ | lysozyme |
| MED25 | mediator complex subunit 25 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NGLY1 | N-glycanase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAPPA2 | pappalysin 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PDE8B | phosphodiesterase 8B |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDZD2 | PDZ domain containing 2 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| POU2F3 | POU class 2 homeobox 3 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPID | peptidylprolyl isomerase D |
| PRKCA | protein kinase C, alpha |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PTGES | prostaglandin E synthase |
| PTN | pleiotrophin |
| RGS4 | regulator of G-protein signaling 4 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPA4 | replication protein A4, 30kDa |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC45A2 | solute carrier family 45, member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| STIP1 | stress-induced phosphoprotein 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TBCD | tubulin folding cofactor D |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNN | tenascin N |
| TRIM2 | tripartite motif containing 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP19 | ubiquitin specific peptidase 19 |
| ZNF7 | zinc finger protein 7 |
| Symbol | Name |
|---|---|
| AGBL5 | ATP/GTP binding protein-like 5 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARHGAP19 | Rho GTPase activating protein 19 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| BMP2 | bone morphogenetic protein 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CBX7 | chromobox homolog 7 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CD2AP | CD2-associated protein |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CFAP44 | cilia and flagella associated protein 44 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| COPS7B | COP9 signalosome subunit 7B |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| E2F8 | E2F transcription factor 8 |
| ENDOG | endonuclease G |
| EPN3 | epsin 3 |
| EXOC3 | exocyst complex component 3 |
| FANCF | Fanconi anemia, complementation group F |
| FCHSD2 | FCH and double SH3 domains 2 |
| FOXD1 | forkhead box D1 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HDAC4 | histone deacetylase 4 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| LRRC6 | leucine rich repeat containing 6 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEF1 | melanoma antigen family F1 |
| MAGEH1 | melanoma antigen family H1 |
| MAP6D1 | MAP6 domain containing 1 |
| METTL2B | methyltransferase like 2B |
| MIS12 | MIS12 kinetochore complex component |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MT1H | metallothionein 1H |
| MUTYH | mutY homolog |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NRSN2 | neurensin 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PEX13 | peroxisomal biogenesis factor 13 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| RAD9A | RAD9 homolog A (S. pombe) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM15 | RNA binding motif protein 15 |
| RGS20 | regulator of G-protein signaling 20 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SDAD1 | SDA1 domain containing 1 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNPH | syntaphilin |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| STX1A | syntaxin 1A (brain) |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM156 | transmembrane protein 156 |
| TMEM2 | transmembrane protein 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAPPC11 | trafficking protein particle complex 11 |
| TROAP | trophinin associated protein |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBXN8 | UBX domain protein 8 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP32 | ubiquitin specific peptidase 32 |
| VASP | vasodilator-stimulated phosphoprotein |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZNF107 | zinc finger protein 107 |
| ZNF177 | zinc finger protein 177 |
| ZNF200 | zinc finger protein 200 |
| ZNF304 | zinc finger protein 304 |
| ZNF324 | zinc finger protein 324 |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF629 | zinc finger protein 629 |
| ZNF675 | zinc finger protein 675 |
| ZNF84 | zinc finger protein 84 |
