| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the alvespimycin-1638 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARG2 | arginase 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| BAG2 | BCL2-associated athanogene 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTH | cystathionine gamma-lyase |
| CTTN | cortactin |
| DCTN1 | dynactin 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DSC2 | desmocollin 2 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| FGFR2 | fibroblast growth factor receptor 2 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HFE | hemochromatosis |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IDS | iduronate 2-sulfatase |
| IFT27 | intraflagellar transport 27 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| LRRC14 | leucine rich repeat containing 14 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED6 | mediator complex subunit 6 |
| MGC12488 | |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MXD4 | MAX dimerization protein 4 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NEK9 | NIMA-related kinase 9 |
| NF2 | neurofibromin 2 (merlin) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHB13 | protocadherin beta 13 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PMP22 | peripheral myelin protein 22 |
| PPID | peptidylprolyl isomerase D |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| RAD51B | RAD51 paralog B |
| RBM5 | RNA binding motif protein 5 |
| RCAN1 | regulator of calcineurin 1 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RPL10 | ribosomal protein L10 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETD2 | SET domain containing 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAI2 | snail family zinc finger 2 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STIP1 | stress-induced phosphoprotein 1 |
| TREX1 | three prime repair exonuclease 1 |
| TXNIP | thioredoxin interacting protein |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF329 | zinc finger protein 329 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANKRD36B | ankyrin repeat domain 36B |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5 | complement component 5 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAPN15 | calpain 15 |
| CCNE1 | cyclin E1 |
| CDC7 | cell division cycle 7 |
| CEP85 | centrosomal protein 85kDa |
| CISH | cytokine inducible SH2-containing protein |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLDN9 | claudin 9 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CROT | carnitine O-octanoyltransferase |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DSE | dermatan sulfate epimerase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| EXO1 | exonuclease 1 |
| FADS3 | fatty acid desaturase 3 |
| FAM102A | family with sequence similarity 102, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHOD1 | formin homology 2 domain containing 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXJ2 | forkhead box J2 |
| FZD4 | frizzled class receptor 4 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| JADE3 | jade family PHD finger 3 |
| JUNB | jun B proto-oncogene |
| KAT2B | K(lysine) acetyltransferase 2B |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0125 | KIAA0125 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL8 | methyltransferase like 8 |
| MID1IP1 | MID1 interacting protein 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRKCD | protein kinase C, delta |
| PROSER1 | proline and serine rich 1 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPATA2L | spermatogenesis associated 2-like |
| SPHK1 | sphingosine kinase 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TFRC | transferrin receptor |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TMEM254 | transmembrane protein 254 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UBQLN4 | ubiquilin 4 |
| ZNF652 | zinc finger protein 652 |
