| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the alvespimycin-4437 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADCY7 | adenylate cyclase 7 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| ANGPT4 | angiopoietin 4 |
| APOE | apolipoprotein E |
| ARG2 | arginase 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARRB1 | arrestin, beta 1 |
| ATG10 | autophagy related 10 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACFD1 | calcium channel flower domain containing 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCND2 | cyclin D2 |
| CD300C | CD300c molecule |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A6 | collagen, type IV, alpha 6 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CROCC | ciliary rootlet coiled-coil, rootletin |
| DFNB31 | deafness, autosomal recessive 31 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FGF4 | fibroblast growth factor 4 |
| FGF6 | fibroblast growth factor 6 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GP5 | glycoprotein V (platelet) |
| GP6 | glycoprotein VI (platelet) |
| HCN2 | hyperpolarization activated cyclic nucleotide gated potassium channel 2 |
| HOPX | HOP homeobox |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HRH3 | histamine receptor H3 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL7R | interleukin 7 receptor |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KEL | Kell blood group, metallo-endopeptidase |
| KIF1A | kinesin family member 1A |
| KLK13 | kallikrein-related peptidase 13 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT17 | keratin 17, type I |
| KRT6A | keratin 6A, type II |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LOXL2 | lysyl oxidase-like 2 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MDFI | MyoD family inhibitor |
| MORN1 | MORN repeat containing 1 |
| NF1 | neurofibromin 1 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDZD2 | PDZ domain containing 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAI2 | retinoic acid induced 2 |
| REEP2 | receptor accessory protein 2 |
| RFPL2 | ret finger protein-like 2 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RGS12 | regulator of G-protein signaling 12 |
| RGS4 | regulator of G-protein signaling 4 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLAMF7 | SLAM family member 7 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SYNPO | synaptopodin |
| TEF | thyrotrophic embryonic factor |
| TGFB2 | transforming growth factor, beta 2 |
| TGM2 | transglutaminase 2 |
| TSC2 | tuberous sclerosis 2 |
| USP22 | ubiquitin specific peptidase 22 |
| WDR33 | WD repeat domain 33 |
| ZNF384 | zinc finger protein 384 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C1S | complement component 1, s subcomponent |
| C3 | complement component 3 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCNO | cyclin O |
| CDH7 | cadherin 7, type 2 |
| CEP295 | centrosomal protein 295kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDN | dendrin |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EFNA3 | ephrin-A3 |
| FBRS | fibrosin |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAS2 | hyaluronan synthase 2 |
| HIST1H4C | histone cluster 1, H4c |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXA10 | homeobox A10 |
| HOXA4 | homeobox A4 |
| HOXA7 | homeobox A7 |
| HOXC10 | homeobox C10 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IL6 | interleukin 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KDM4D | lysine (K)-specific demethylase 4D |
| KIRREL | kin of IRRE like (Drosophila) |
| KLK7 | kallikrein-related peptidase 7 |
| MCM10 | minichromosome maintenance complex component 10 |
| MMRN2 | multimerin 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC3A | mucin 3A, cell surface associated |
| NCALD | neurocalcin delta |
| NOL10 | nucleolar protein 10 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| ODF2 | outer dense fiber of sperm tails 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLA1A | phospholipase A1 member A |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRR15L | proline rich 15-like |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF122 | ring finger protein 122 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SH2D2A | SH2 domain containing 2A |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMO | smoothened, frizzled class receptor |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| THRB | thyroid hormone receptor, beta |
| TLR1 | toll-like receptor 1 |
| TMEM206 | transmembrane protein 206 |
| TRIM9 | tripartite motif containing 9 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| VASH1 | vasohibin 1 |
| WDR25 | WD repeat domain 25 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF232 | zinc finger protein 232 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZXDC | ZXD family zinc finger C |
