| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alvespimycin-5210 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABHD4 | abhydrolase domain containing 4 |
| ABI2 | abl-interactor 2 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| ADRA1D | adrenoceptor alpha 1D |
| AR | androgen receptor |
| ATF7IP | activating transcription factor 7 interacting protein |
| BAG2 | BCL2-associated athanogene 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CACYBP | calcyclin binding protein |
| CCNG2 | cyclin G2 |
| CD6 | CD6 molecule |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CUL7 | cullin 7 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DUSP13 | dual specificity phosphatase 13 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| FCMR | Fc fragment of IgM receptor |
| FGFR2 | fibroblast growth factor receptor 2 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GAS7 | growth arrest-specific 7 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IRS2 | insulin receptor substrate 2 |
| ITGA8 | integrin, alpha 8 |
| JAG1 | jagged 1 |
| KLK6 | kallikrein-related peptidase 6 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MICB | MHC class I polypeptide-related sequence B |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MSX1 | msh homeobox 1 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NF1 | neurofibromin 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OSBPL1A | oxysterol binding protein-like 1A |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PLA2G3 | phospholipase A2, group III |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPID | peptidylprolyl isomerase D |
| PXN | paxillin |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A13 | S100 calcium binding protein A13 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRCAP | Snf2-related CREBBP activator protein |
| TBC1D19 | TBC1 domain family, member 19 |
| TES | testin LIM domain protein |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPMT | thiopurine S-methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VLDLR | very low density lipoprotein receptor |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF350 | zinc finger protein 350 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ANKRD36B | ankyrin repeat domain 36B |
| APOD | apolipoprotein D |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCNO | cyclin O |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFAP44 | cilia and flagella associated protein 44 |
| CFD | complement factor D (adipsin) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CISH | cytokine inducible SH2-containing protein |
| CTSK | cathepsin K |
| CUL9 | cullin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUSP8 | dual specificity phosphatase 8 |
| E2F8 | E2F transcription factor 8 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| EGR3 | early growth response 3 |
| ERCC8 | excision repair cross-complementation group 8 |
| FZD4 | frizzled class receptor 4 |
| GALK1 | galactokinase 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GLI3 | GLI family zinc finger 3 |
| GPR19 | G protein-coupled receptor 19 |
| HIST1H2AJ | histone cluster 1, H2aj |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFT20 | intraflagellar transport 20 |
| IRX5 | iroquois homeobox 5 |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LAMA3 | laminin, alpha 3 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NRSN2 | neurensin 2 |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like |
| PRKCD | protein kinase C, delta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM15B | RNA binding motif protein 15B |
| RBM38 | RNA binding motif protein 38 |
| RECQL4 | RecQ protein-like 4 |
| RGS16 | regulator of G-protein signaling 16 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SMAD7 | SMAD family member 7 |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STRN | striatin, calmodulin binding protein |
| SYTL2 | synaptotagmin-like 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TFRC | transferrin receptor |
| TMEM180 | transmembrane protein 180 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| WDR91 | WD repeat domain 91 |
| YEATS2 | YEATS domain containing 2 |
| ZNF239 | zinc finger protein 239 |
| ZXDC | ZXD family zinc finger C |
