| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alvespimycin-5573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CCDC81 | coiled-coil domain containing 81 |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CEP72 | centrosomal protein 72kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL1A1 | collagen, type I, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CSF1R | colony stimulating factor 1 receptor |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DBF4B | DBF4 zinc finger B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DMXL2 | Dmx-like 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DOCK10 | dedicator of cytokinesis 10 |
| EDNRA | endothelin receptor type A |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| FAM46C | family with sequence similarity 46, member C |
| FCAR | Fc fragment of IgA receptor |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| FZD7 | frizzled class receptor 7 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HAP1 | huntingtin-associated protein 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HMOX1 | heme oxygenase 1 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL6R | interleukin 6 receptor |
| JAG1 | jagged 1 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LAT2 | linker for activation of T cells family, member 2 |
| LIF | leukemia inhibitory factor |
| LMAN1 | lectin, mannose-binding, 1 |
| MICB | MHC class I polypeptide-related sequence B |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NCOA2 | nuclear receptor coactivator 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG2 | NDRG family member 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPID | peptidylprolyl isomerase D |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAI2 | retinoic acid induced 2 |
| RBM5 | RNA binding motif protein 5 |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TBX3 | T-box 3 |
| TES | testin LIM domain protein |
| TGM2 | transglutaminase 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZNF10 | zinc finger protein 10 |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF224 | zinc finger protein 224 |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF329 | zinc finger protein 329 |
| ZNF614 | zinc finger protein 614 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACSF2 | acyl-CoA synthetase family member 2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKRD36B | ankyrin repeat domain 36B |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CDK3 | cyclin-dependent kinase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN15 | claudin 15 |
| CST6 | cystatin E/M |
| CUL9 | cullin 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM120C | family with sequence similarity 120C |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GAMT | guanidinoacetate N-methyltransferase |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| GMPR | guanosine monophosphate reductase |
| GPR19 | G protein-coupled receptor 19 |
| GRB7 | growth factor receptor-bound protein 7 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2AI | histone cluster 1, H2ai |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IQCC | IQ motif containing C |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLF2 | Kruppel-like factor 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT8P12 | keratin 8 pseudogene 12 |
| LHX6 | LIM homeobox 6 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MUTYH | mutY homolog |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NEK11 | NIMA-related kinase 11 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOP2 | NOP2 nucleolar protein |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTF3 | neurotrophin 3 |
| ONECUT2 | one cut homeobox 2 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE8B | phosphodiesterase 8B |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLK3 | polo-like kinase 3 |
| POM121 | POM121 transmembrane nucleoporin |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKCD | protein kinase C, delta |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PUS1 | pseudouridylate synthase 1 |
| RGS16 | regulator of G-protein signaling 16 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SYTL2 | synaptotagmin-like 2 |
| TAOK1 | TAO kinase 1 |
| TCHH | trichohyalin |
| TCTN2 | tectonic family member 2 |
| TMEM121 | transmembrane protein 121 |
| TMEM39B | transmembrane protein 39B |
| TNS2 | tensin 2 |
| TPCN1 | two pore segment channel 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| VPS9D1 | VPS9 domain containing 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
