| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the alvespimycin-6172 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA2C | adrenoceptor alpha 2C |
| AGRP | agouti related neuropeptide |
| ANGPT4 | angiopoietin 4 |
| ANGPTL2 | angiopoietin-like 2 |
| APCS | amyloid P component, serum |
| ARSE | arylsulfatase E (chondrodysplasia punctata 1) |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BAG3 | BCL2-associated athanogene 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BIN1 | bridging integrator 1 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CLDN11 | claudin 11 |
| CRYZ | crystallin, zeta (quinone reductase) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DSCAM | Down syndrome cell adhesion molecule |
| ELK1 | ELK1, member of ETS oncogene family |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPS8L3 | EPS8-like 3 |
| FAM13A | family with sequence similarity 13, member A |
| FGF9 | fibroblast growth factor 9 |
| FLT4 | fms-related tyrosine kinase 4 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GAMT | guanidinoacetate N-methyltransferase |
| GAS8 | growth arrest-specific 8 |
| GRIA4 | glutamate receptor, ionotropic, AMPA 4 |
| HFE | hemochromatosis |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXB2 | homeobox B2 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL36G | interleukin 36, gamma |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAD1 | ladinin 1 |
| LMF1 | lipase maturation factor 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLXIP | MLX interacting protein |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NIN | ninein (GSK3B interacting protein) |
| NLRP1 | NLR family, pyrin domain containing 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OSBPL7 | oxysterol binding protein-like 7 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PLAC4 | placenta-specific 4 |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRKCH | protein kinase C, eta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| REC8 | REC8 meiotic recombination protein |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SV2B | synaptic vesicle glycoprotein 2B |
| TCF3 | transcription factor 3 |
| TCL1B | T-cell leukemia/lymphoma 1B |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TRGV5 | T cell receptor gamma variable 5 |
| TRIM2 | tripartite motif containing 2 |
| TRIM3 | tripartite motif containing 3 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSPAN9 | tetraspanin 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TYRO3 | TYRO3 protein tyrosine kinase |
| UBE3A | ubiquitin protein ligase E3A |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| AEN | apoptosis enhancing nuclease |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| AVEN | apoptosis, caspase activation inhibitor |
| AXIN1 | axin 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC86 | coiled-coil domain containing 86 |
| CD101 | CD101 molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPT | centromere protein T |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHMP7 | charged multivesicular body protein 7 |
| CTSD | cathepsin D |
| CTSV | cathepsin V |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOLPP1 | dolichyldiphosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| ELP5 | elongator acetyltransferase complex subunit 5 |
| FADS2 | fatty acid desaturase 2 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM57A | family with sequence similarity 57, member A |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLCN | folliculin |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2BI | histone cluster 1, H2bi |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LHFP | lipoma HMGIC fusion partner |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LY6E | lymphocyte antigen 6 complex, locus E |
| METTL1 | methyltransferase like 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NCALD | neurocalcin delta |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| POLM | polymerase (DNA directed), mu |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF121 | ring finger protein 121 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SIL1 | SIL1 nucleotide exchange factor |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMAD7 | SMAD family member 7 |
| SMYD5 | SMYD family member 5 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPON2 | spondin 2, extracellular matrix protein |
| SURF2 | surfeit 2 |
| TAOK1 | TAO kinase 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TFB2M | transcription factor B2, mitochondrial |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TRIM58 | tripartite motif containing 58 |
| UNC13B | unc-13 homolog B (C. elegans) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR43 | WD repeat domain 43 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF322P1 | zinc finger protein 322 pseudogene 1 |
| ZNF74 | zinc finger protein 74 |
