| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the alvespimycin-6933 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADCY7 | adenylate cyclase 7 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AMACR | alpha-methylacyl-CoA racemase |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAG2 | BCL2-associated athanogene 2 |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CACFD1 | calcium channel flower domain containing 1 |
| CACYBP | calcyclin binding protein |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCNG2 | cyclin G2 |
| CD4 | CD4 molecule |
| CEMP1 | cementum protein 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTBS | chitobiase, di-N-acetyl- |
| DCLK2 | doublecortin-like kinase 2 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EED | embryonic ectoderm development |
| ELL | elongation factor RNA polymerase II |
| FBXO40 | F-box protein 40 |
| FOXJ3 | forkhead box J3 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HR | hair growth associated |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1RN | interleukin 1 receptor antagonist |
| ISG15 | ISG15 ubiquitin-like modifier |
| KDM4B | lysine (K)-specific demethylase 4B |
| KRT31 | keratin 31, type I |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MYLK | myosin light chain kinase |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NFYA | nuclear transcription factor Y, alpha |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE11A | phosphodiesterase 11A |
| PLAT | plasminogen activator, tissue |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPID | peptidylprolyl isomerase D |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS2 | regulator of G-protein signaling 2 |
| RNF19B | ring finger protein 19B |
| RPL10 | ribosomal protein L10 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMC4 | structural maintenance of chromosomes 4 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| STC1 | stanniocalcin 1 |
| SYNC | syncoilin, intermediate filament protein |
| SYNM | synemin, intermediate filament protein |
| TES | testin LIM domain protein |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLN2 | talin 2 |
| TSPYL2 | TSPY-like 2 |
| TUBGCP3 | tubulin, gamma complex associated protein 3 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VLDLR | very low density lipoprotein receptor |
| WIZ | widely interspaced zinc finger motifs |
| ZNF10 | zinc finger protein 10 |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF227 | zinc finger protein 227 |
| ZNF516 | zinc finger protein 516 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BTBD2 | BTB (POZ) domain containing 2 |
| BYSL | bystin-like |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC88C | coiled-coil domain containing 88C |
| CCS | copper chaperone for superoxide dismutase |
| CD151 | CD151 molecule (Raph blood group) |
| CD302 | CD302 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CLDN9 | claudin 9 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DUSP4 | dual specificity phosphatase 4 |
| E2F8 | E2F transcription factor 8 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EGR3 | early growth response 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERF | Ets2 repressor factor |
| FAM155B | family with sequence similarity 155, member B |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBPL | FK506 binding protein like |
| FOXD1 | forkhead box D1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FZD4 | frizzled class receptor 4 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HOXC13 | homeobox C13 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLC2 | kinesin light chain 2 |
| KLF10 | Kruppel-like factor 10 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMA3 | laminin, alpha 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| METTL1 | methyltransferase like 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRIP1 | nuclear receptor interacting protein 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLK2 | polo-like kinase 2 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRKCD | protein kinase C, delta |
| PRR14L | proline rich 14-like |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SETD6 | SET domain containing 6 |
| SHROOM2 | shroom family member 2 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SYTL2 | synaptotagmin-like 2 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFRC | transferrin receptor |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM104 | transmembrane protein 104 |
| TMEM127 | transmembrane protein 127 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIM52 | tripartite motif containing 52 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| ZNF768 | zinc finger protein 768 |
| ZXDC | ZXD family zinc finger C |
