| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the alvespimycin-6973 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADCY7 | adenylate cyclase 7 |
| AURKA | aurora kinase A |
| AVPR1B | arginine vasopressin receptor 1B |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BMP4 | bone morphogenetic protein 4 |
| BST2 | bone marrow stromal cell antigen 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CD209 | CD209 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIDO1 | death inducer-obliterator 1 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EGR1 | early growth response 1 |
| FAM155A | family with sequence similarity 155, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GM2A | GM2 ganglioside activator |
| GPC1 | glypican 1 |
| HFE | hemochromatosis |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IAPP | islet amyloid polypeptide |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL11 | interleukin 11 |
| KIF13B | kinesin family member 13B |
| KLHL28 | kelch-like family member 28 |
| KLK6 | kallikrein-related peptidase 6 |
| LRRC23 | leucine rich repeat containing 23 |
| MAP4 | microtubule-associated protein 4 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MED6 | mediator complex subunit 6 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MYOZ3 | myozenin 3 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLK | nemo-like kinase |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLA2G3 | phospholipase A2, group III |
| PLAT | plasminogen activator, tissue |
| POM121 | POM121 transmembrane nucleoporin |
| PPID | peptidylprolyl isomerase D |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RB1 | retinoblastoma 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RIN2 | Ras and Rab interactor 2 |
| RNF39 | ring finger protein 39 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMC4 | structural maintenance of chromosomes 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SQSTM1 | sequestosome 1 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SSPN | sarcospan |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| TRIM10 | tripartite motif containing 10 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| UPK3B | uroplakin 3B |
| ZNF16 | zinc finger protein 16 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF230 | zinc finger protein 230 |
| ZNF41 | zinc finger protein 41 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADCY3 | adenylate cyclase 3 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKRD40 | ankyrin repeat domain 40 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATP13A2 | ATPase type 13A2 |
| BCL2L2 | BCL2-like 2 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CENPQ | centromere protein Q |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHEK2 | checkpoint kinase 2 |
| CLDN4 | claudin 4 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK1 | dedicator of cytokinesis 1 |
| E2F8 | E2F transcription factor 8 |
| EPPK1 | epiplakin 1 |
| EXO1 | exonuclease 1 |
| FAM192A | family with sequence similarity 192, member A |
| FAM63A | family with sequence similarity 63, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLMN | glomulin, FKBP associated protein |
| GPR19 | G protein-coupled receptor 19 |
| HCFC2 | host cell factor C2 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIZ | kizuna centrosomal protein |
| LAMA5 | laminin, alpha 5 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MID1IP1 | MID1 interacting protein 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLK2 | polo-like kinase 2 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PRSS8 | protease, serine, 8 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF113A | ring finger protein 113A |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETD6 | SET domain containing 6 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPATA2L | spermatogenesis associated 2-like |
| STAG3 | stromal antigen 3 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STX5 | syntaxin 5 |
| SYTL2 | synaptotagmin-like 2 |
| TBCC | tubulin folding cofactor C |
| TCTA | T-cell leukemia translocation altered |
| TFRC | transferrin receptor |
| THAP11 | THAP domain containing 11 |
| THEM6 | thioesterase superfamily member 6 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIB1 | tribbles pseudokinase 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| WDR60 | WD repeat domain 60 |
| ZNF354A | zinc finger protein 354A |
| ZNF668 | zinc finger protein 668 |
| ZXDC | ZXD family zinc finger C |
