| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the alvespimycin-993 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD4 | abhydrolase domain containing 4 |
| ACVR1B | activin A receptor, type IB |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AFF2 | AF4/FMR2 family, member 2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AQP1 | aquaporin 1 (Colton blood group) |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BIN1 | bridging integrator 1 |
| BMP5 | bone morphogenetic protein 5 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXORF21 | chromosome X open reading frame 21 |
| DBF4B | DBF4 zinc finger B |
| DICER1 | dicer 1, ribonuclease type III |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHB2 | EPH receptor B2 |
| FAM46C | family with sequence similarity 46, member C |
| FLT1 | fms-related tyrosine kinase 1 |
| FOXG1 | forkhead box G1 |
| GLS | glutaminase |
| GPX2 | glutathione peroxidase 2 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HFE | hemochromatosis |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFT27 | intraflagellar transport 27 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MGC12488 | |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MTMR8 | myotubularin related protein 8 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NCBP1 | nuclear cap binding protein subunit 1, 80kDa |
| NDRG1 | N-myc downstream regulated 1 |
| NMT2 | N-myristoyltransferase 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE12 | phosphodiesterase 12 |
| PGF | placental growth factor |
| PHOX2B | paired-like homeobox 2b |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PKP1 | plakophilin 1 |
| PLK4 | polo-like kinase 4 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRLR | prolactin receptor |
| PRSS16 | protease, serine, 16 (thymus) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAI2 | snail family zinc finger 2 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STAT5A | signal transducer and activator of transcription 5A |
| TAF4 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TGFA | transforming growth factor, alpha |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM53 | transmembrane protein 53 |
| TSPYL2 | TSPY-like 2 |
| VLDLR | very low density lipoprotein receptor |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF10 | zinc finger protein 10 |
| ZNF16 | zinc finger protein 16 |
| ZNF197 | zinc finger protein 197 |
| ZNF227 | zinc finger protein 227 |
| ZNF329 | zinc finger protein 329 |
| ZNF419 | zinc finger protein 419 |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAGE | B melanoma antigen |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CBX4 | chromobox homolog 4 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DSE | dermatan sulfate epimerase |
| EGR3 | early growth response 3 |
| EPN3 | epsin 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM155B | family with sequence similarity 155, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FPGS | folylpolyglutamate synthase |
| GPR19 | G protein-coupled receptor 19 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IRX5 | iroquois homeobox 5 |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIZ | kizuna centrosomal protein |
| KLF10 | Kruppel-like factor 10 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MANSC1 | MANSC domain containing 1 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MICALL2 | MICAL-like 2 |
| MTRF1 | mitochondrial translational release factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCS1 | neuronal calcium sensor 1 |
| NMU | neuromedin U |
| NUPL2 | nucleoporin like 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PGPEP1 | pyroglutamyl-peptidase I |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRKCD | protein kinase C, delta |
| PRMT7 | protein arginine methyltransferase 7 |
| PUS1 | pseudouridylate synthase 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RBBP6 | retinoblastoma binding protein 6 |
| RBM14 | RNA binding motif protein 14 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2B2 | SH2B adaptor protein 2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPATA2L | spermatogenesis associated 2-like |
| SYTL2 | synaptotagmin-like 2 |
| TBC1D31 | TBC1 domain family, member 31 |
| TFRC | transferrin receptor |
| TJP3 | tight junction protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRAPPC12 | trafficking protein particle complex 12 |
| UBQLN4 | ubiquilin 4 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF239 | zinc finger protein 239 |
