alzheimers Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A dementia that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting in late middle age and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. It is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability.|A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.|A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)|A dementia which is an incurable disease of unknown cause, starting in late middle age or in old age, that results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood, that leads in advanced cases to a profound decline in cognitive and physical functioning, and that is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. (Experimental Factor Ontology, EFO_0000249)
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Genes

642 genes co-occuring with the biological term alzheimers in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAP1 ArfGAP with dual PH domains 1
ADORA2A adenosine A2a receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AGRN agrin
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAS1 5'-aminolevulinate synthase 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
AMIGO2 adhesion molecule with Ig-like domain 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANPEP alanyl (membrane) aminopeptidase
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APH1A APH1A gamma secretase subunit
APOA1 apolipoprotein A-I
APOC1 apolipoprotein C-I
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
ARC activity-regulated cytoskeleton-associated protein
ARMS2 age-related maculopathy susceptibility 2
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF4 activating transcription factor 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATXN8OS ATXN8 opposite strand (non-protein coding)
AVP arginine vasopressin
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAG1 BCL2-associated athanogene
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BIN1 bridging integrator 1
BLM Bloom syndrome, RecQ helicase-like
BLMH bleomycin hydrolase
BLVRA biliverdin reductase A
BMP6 bone morphogenetic protein 6
BSG basigin (Ok blood group)
C1R complement component 1, r subcomponent
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
C9ORF72 chromosome 9 open reading frame 72
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CACUL1 CDK2-associated, cullin domain 1
CALHM1 calcium homeostasis modulator 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CARD8 caspase recruitment domain family, member 8
CARTPT CART prepropeptide
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CCL15 chemokine (C-C motif) ligand 15
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCNC cyclin C
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD274 CD274 molecule
CD2AP CD2-associated protein
CD33 CD33 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK1 cyclin-dependent kinase 1
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CELF1 CUGBP, Elav-like family member 1
CELF2 CUGBP, Elav-like family member 2
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHAT choline O-acetyltransferase
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHGA chromogranin A
CHGB chromogranin B
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CHRM2 cholinergic receptor, muscarinic 2
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIZ1 CDKN1A interacting zinc finger protein 1
CKB creatine kinase, brain
CLOCK clock circadian regulator
CLSTN1 calsyntenin 1
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CNTNAP2 contactin associated protein-like 2
COL18A1 collagen, type XVIII, alpha 1
COL25A1 collagen, type XXV, alpha 1
COMT catechol-O-methyltransferase
CORT cortistatin
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
COX15 cytochrome c oxidase assembly homolog 15 (yeast)
COX4I1 cytochrome c oxidase subunit IV isoform 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB1 cAMP responsive element binding protein 1
CREM cAMP responsive element modulator
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSNK1D casein kinase 1, delta
CST3 cystatin C
CTGF connective tissue growth factor
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND2 catenin (cadherin-associated protein), delta 2
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CTSS cathepsin S
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CYBB cytochrome b-245, beta polypeptide
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAOA D-amino acid oxidase activator
DAPK1 death-associated protein kinase 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DBN1 drebrin 1
DDIT4 DNA-damage-inducible transcript 4
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DEFB1 defensin, beta 1
DERL1 derlin 1
DHCR24 24-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLG4 discs, large homolog 4 (Drosophila)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNM1L dynamin 1-like
DNM2 dynamin 2
DNMBP dynamin binding protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK2 dedicator of cytokinesis 2
DPYSL2 dihydropyrimidinase-like 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DUSP22 dual specificity phosphatase 22
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ECE1 endothelin converting enzyme 1
ECE2 endothelin converting enzyme 2
EDN1 endothelin 1
EGF epidermal growth factor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELK1 ELK1, member of ETS oncogene family
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
EPHA1 EPH receptor A1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXOC3L2 exocyst complex component 3-like 2
F2 coagulation factor II (thrombin)
FAAH fatty acid amide hydrolase
FABP3 fatty acid binding protein 3, muscle and heart
FAS Fas cell surface death receptor
FGB fibrinogen beta chain
FGF1 fibroblast growth factor 1 (acidic)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP1A FK506 binding protein 1A, 12kDa
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FLOT1 flotillin 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXO3 forkhead box O3
FRK fyn-related Src family tyrosine kinase
FSHR follicle stimulating hormone receptor
FTMT ferritin mitochondrial
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GFAP glial fibrillary acidic protein
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GLB1 galactosidase, beta 1
GLRX glutaredoxin (thioltransferase)
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOLM1 golgi membrane protein 1
GPC1 glypican 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
GRM2 glutamate receptor, metabotropic 2
GRM5 glutamate receptor, metabotropic 5
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
GSTM1 glutathione S-transferase mu 1
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HCRT hypocretin (orexin) neuropeptide precursor
HECTD2 HECT domain containing E3 ubiquitin protein ligase 2
HEXB hexosaminidase B (beta polypeptide)
HFE hemochromatosis
HIST3H3 histone cluster 3, H3
HK1 hexokinase 1
HLA-A major histocompatibility complex, class I, A
HMGA1 high mobility group AT-hook 1
HMGB1 high mobility group box 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HNMT histamine N-methyltransferase
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HOMER1 homer scaffolding protein 1
HP haptoglobin
HPSE heparanase
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HRH3 histamine receptor H3
HRH4 histamine receptor H4
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB8 heat shock 22kDa protein 8
HSPG2 heparan sulfate proteoglycan 2
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IDO1 indoleamine 2,3-dioxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL3 interleukin 3
IL32 interleukin 32
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INS insulin
IREB2 iron-responsive element binding protein 2
IRS1 insulin receptor substrate 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2B integral membrane protein 2B
ITPKB inositol-trisphosphate 3-kinase B
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
KAT5 K(lysine) acetyltransferase 5
KCNIP3 Kv channel interacting protein 3, calsenilin
KCTD2 potassium channel tetramerization domain containing 2
KIDINS220 kinase D-interacting substrate, 220kDa
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLC1 kinesin light chain 1
KLF2 Kruppel-like factor 2
KLK3 kallikrein-related peptidase 3
KLK6 kallikrein-related peptidase 6
LCN2 lipocalin 2
LDLR low density lipoprotein receptor
LDOC1 leucine zipper, down-regulated in cancer 1
LEP leptin
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LIF leukemia inhibitory factor
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIPC lipase, hepatic
LNPEP leucyl/cystinyl aminopeptidase
LOC100128226 hypothetic protein
LOC643387 TAR DNA binding protein pseudogene
LOC646506 lysosomal-associated membrane protein 1 pseudogene
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LRP6 low density lipoprotein receptor-related protein 6
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRC15 leucine rich repeat containing 15
LRRK2 leucine-rich repeat kinase 2
LRRTM3 leucine rich repeat transmembrane neuronal 3
LTF lactotransferrin
MADD MAP-kinase activating death domain
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2 microtubule-associated protein 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MBP myelin basic protein
MEF2A myocyte enhancer factor 2A
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR107 microRNA 107
MIR124-1 microRNA 124-1
MIR125A microRNA 125a
MIR125B1 microRNA 125b-1
MIR132 microRNA 132
MIR146A microRNA 146a
MIR212 microRNA 212
MIR27A microRNA 27a
MIR29A microRNA 29a
MIR29B1 microRNA 29b-1
MME membrane metallo-endopeptidase
MMEL1 membrane metallo-endopeptidase-like 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOBP myelin-associated oligodendrocyte basic protein
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1A melatonin receptor 1A
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MZF1 myeloid zinc finger 1
NCAM1 neural cell adhesion molecule 1
NCSTN nicastrin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGB neuroglobin
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NINJ2 ninjurin 2
NLRP3 NLR family, pyrin domain containing 3
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NOTCH4 notch 4
NPC1 Niemann-Pick disease, type C1
NPEPPS aminopeptidase puromycin sensitive
NPTXR neuronal pentraxin receptor
NPY neuropeptide Y
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPRD1 opioid receptor, delta 1
OXT oxytocin/neurophysin I prepropeptide
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PAWR PRKC, apoptosis, WT1, regulator
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDCD1 programmed cell death 1
PDE8B phosphodiesterase 8B
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDIA5 protein disulfide isomerase family A, member 5
PDYN prodynorphin
PEMT phosphatidylethanolamine N-methyltransferase
PER1 period circadian clock 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITRM1 pitrilysin metallopeptidase 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLG plasminogen
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PLTP phospholipid transfer protein
PLXNA4 plexin A4
PMCH pro-melanin-concentrating hormone
PNP purine nucleoside phosphorylase
POLB polymerase (DNA directed), beta
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPID peptidylprolyl isomerase D
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDX6 peroxiredoxin 6
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCZ protein kinase C, zeta
PRND prion protein 2 (dublet)
PRNP prion protein
PSEN1 presenilin 1
PSEN2 presenilin 2
PSENEN presenilin enhancer gamma secretase subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
PURA purine-rich element binding protein A
QPCT glutaminyl-peptide cyclotransferase
RAB5A RAB5A, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAN RAN, member RAS oncogene family
RB1CC1 RB1-inducible coiled-coil 1
RCAN1 regulator of calcineurin 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELN reelin
RFC1 replication factor C (activator 1) 1, 145kDa
RGS4 regulator of G-protein signaling 4
RHOA ras homolog family member A
RNF146 ring finger protein 146
RNPEP arginyl aminopeptidase (aminopeptidase B)
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RTN3 reticulon 3
RTN4R reticulon 4 receptor
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1
RUMY2 RUMY family member 2
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
RYR3 ryanodine receptor 3
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG3 secretogranin III
SCGN secretagogin, EF-hand calcium binding protein
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SET SET nuclear proto-oncogene
SETX senataxin
SFPQ splicing factor proline/glutamine-rich
SGMS1 sphingomyelin synthase 1
SHBG sex hormone-binding globulin
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT2 sirtuin 2
SIRT3 sirtuin 3
SLC10A4 solute carrier family 10, member 4
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC30A10 solute carrier family 30, member 10
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC30A6 solute carrier family 30 (zinc transporter), member 6
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAP25 synaptosomal-associated protein, 25kDa
SNAP91 synaptosomal-associated protein, 91kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SNX12 sorting nexin 12
SOAT1 sterol O-acyltransferase 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SORCS1 sortilin-related VPS10 domain containing receptor 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SORT1 sortilin 1
SOS2 son of sevenless homolog 2 (Drosophila)
SP1 Sp1 transcription factor
SP4 Sp4 transcription factor
SQSTM1 sequestosome 1
SST somatostatin
STH saitohin
STMN1 stathmin 1
STOX1 storkhead box 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX8 syntaxin 8
SYP synaptophysin
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TACR2 tachykinin receptor 2
TARDBP TAR DNA binding protein
TBP TATA box binding protein
TET1 tet methylcytosine dioxygenase 1
TF transferrin
TFAM transcription factor A, mitochondrial
TFCP2 transcription factor CP2
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THRB thyroid hormone receptor, beta
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMEM106B transmembrane protein 106B
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP73 tumor protein p73
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TREM1 triggering receptor expressed on myeloid cells 1
TREM2 triggering receptor expressed on myeloid cells 2
TREML2 triggering receptor expressed on myeloid cells-like 2
TRIP4 thyroid hormone receptor interactor 4
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSC2 tuberous sclerosis 2
TTBK1 tau tubulin kinase 1
TTR transthyretin
TXN thioredoxin
UBB ubiquitin B
UBQLN1 ubiquilin 1
UBXN4 UBX domain protein 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
WWC1 WW and C2 domain containing 1
XBP1 X-box binding protein 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZYX zyxin