amantadine-1344 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the amantadine-1344 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
AEN apoptosis enhancing nuclease
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
B3GAT3 beta-1,3-glucuronyltransferase 3
BAHCC1 BAH domain and coiled-coil containing 1
BBS9 Bardet-Biedl syndrome 9
BCL2L1 BCL2-like 1
C16ORF59 chromosome 16 open reading frame 59
C1RL complement component 1, r subcomponent-like
C22ORF29 chromosome 22 open reading frame 29
CACTIN cactin, spliceosome C complex subunit
CAPN15 calpain 15
CD180 CD180 molecule
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CENPT centromere protein T
CEP170B centrosomal protein 170B
CEP250 centrosomal protein 250kDa
CHD3 chromodomain helicase DNA binding protein 3
CLASRP CLK4-associating serine/arginine rich protein
CLTB clathrin, light chain B
CRTC1 CREB regulated transcription coactivator 1
CTDNEP1 CTD nuclear envelope phosphatase 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30
DPP4 dipeptidyl-peptidase 4
ELP6 elongator acetyltransferase complex subunit 6
EML3 echinoderm microtubule associated protein like 3
ERCC2 excision repair cross-complementation group 2
ESRRA estrogen-related receptor alpha
FBXL15 F-box and leucine-rich repeat protein 15
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FKBP8 FK506 binding protein 8, 38kDa
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HCFC1 host cell factor C1
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
INO80B INO80 complex subunit B
INO80D INO80 complex subunit D
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
KIF3C kinesin family member 3C
LPPR3 lipid phosphate phosphatase-related protein type 3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MADD MAP-kinase activating death domain
MAP4 microtubule-associated protein 4
MAST2 microtubule associated serine/threonine kinase 2
MBD3 methyl-CpG binding domain protein 3
MED27 mediator complex subunit 27
MEF2D myocyte enhancer factor 2D
MXD3 MAX dimerization protein 3
MXD4 MAX dimerization protein 4
MYH14 myosin, heavy chain 14, non-muscle
MYH15 myosin, heavy chain 15
MZT2B mitotic spindle organizing protein 2B
NCOA1 nuclear receptor coactivator 1
NDE1 nudE neurodevelopment protein 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCGF2 polycomb group ring finger 2
PEX6 peroxisomal biogenesis factor 6
PHF7 PHD finger protein 7
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG1 phospholipase C, gamma 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRDX2 peroxiredoxin 2
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PROS1 protein S (alpha)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RECQL5 RecQ protein-like 5
RUNX3 runt-related transcription factor 3
SEC24D SEC24 family member D
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SF3A2 splicing factor 3a, subunit 2, 66kDa
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIN3B SIN3 transcription regulator family member B
SIPA1 signal-induced proliferation-associated 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STOML1 stomatin (EPB72)-like 1
SURF1 surfeit 1
SYNGR1 synaptogyrin 1
TACC3 transforming, acidic coiled-coil containing protein 3
TBL1X transducin (beta)-like 1X-linked
TEP1 telomerase-associated protein 1
THOP1 thimet oligopeptidase 1
TMEM246 transmembrane protein 246
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZMYND8 zinc finger, MYND-type containing 8
ZNF236 zinc finger protein 236

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM10 ADAM metallopeptidase domain 10
AIDA axin interactor, dorsalization associated
APOL6 apolipoprotein L, 6
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BBS10 Bardet-Biedl syndrome 10
BPGM 2,3-bisphosphoglycerate mutase
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF30 chromosome 11 open reading frame 30
C21ORF91 chromosome 21 open reading frame 91
CEP97 centrosomal protein 97kDa
CISH cytokine inducible SH2-containing protein
CLDND1 claudin domain containing 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBR1 debranching RNA lariats 1
DGAT1 diacylglycerol O-acyltransferase 1
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
EXOC2 exocyst complex component 2
EXOC5 exocyst complex component 5
FKBP14 FK506 binding protein 14, 22 kDa
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GDE1 glycerophosphodiester phosphodiesterase 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPHN gephyrin
GTF2I general transcription factor IIi
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HP1BP3 heterochromatin protein 1, binding protein 3
ICK intestinal cell (MAK-like) kinase
IGSF6 immunoglobulin superfamily, member 6
IREB2 iron-responsive element binding protein 2
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LIG4 ligase IV, DNA, ATP-dependent
LMAN1 lectin, mannose-binding, 1
LPAR4 lysophosphatidic acid receptor 4
MAGOHB mago-nashi homolog B (Drosophila)
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MCMBP minichromosome maintenance complex binding protein
METTL21B methyltransferase like 21B
MTMR6 myotubularin related protein 6
MYO5C myosin VC
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NPIPB3 nuclear pore complex interacting protein family, member B3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGM3 phosphoglucomutase 3
PIBF1 progesterone immunomodulatory binding factor 1
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PRRC1 proline-rich coiled-coil 1
PSAT1 phosphoserine aminotransferase 1
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PTER phosphotriesterase related
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB23 RAB23, member RAS oncogene family
RFX7 regulatory factor X, 7
RNF146 ring finger protein 146
SAMD9 sterile alpha motif domain containing 9
SCD5 stearoyl-CoA desaturase 5
SCYL2 SCY1-like 2 (S. cerevisiae)
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SGMS1 sphingomyelin synthase 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC25A40 solute carrier family 25, member 40
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPIN1 spindlin 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
THRAP3 thyroid hormone receptor associated protein 3
TLR1 toll-like receptor 1
TLR4 toll-like receptor 4
TMEM50B transmembrane protein 50B
TRIM22 tripartite motif containing 22
TRIM25 tripartite motif containing 25
TTF2 transcription termination factor, RNA polymerase II
WDR60 WD repeat domain 60
XAF1 XIAP associated factor 1
YIPF5 Yip1 domain family, member 5
ZBTB6 zinc finger and BTB domain containing 6
ZNF124 zinc finger protein 124
ZNF665 zinc finger protein 665