| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the amantadine-3280 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACVR1B | activin A receptor, type IB |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AMH | anti-Mullerian hormone |
| ANGEL2 | angel homolog 2 (Drosophila) |
| APOM | apolipoprotein M |
| ASPH | aspartate beta-hydroxylase |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| B9D1 | B9 protein domain 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCDC132 | coiled-coil domain containing 132 |
| CCNG2 | cyclin G2 |
| CDC25A | cell division cycle 25A |
| CDC25C | cell division cycle 25C |
| CEP250 | centrosomal protein 250kDa |
| CHKB | choline kinase beta |
| COL11A2 | collagen, type XI, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTAGE5 | CTAGE family, member 5 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DSC2 | desmocollin 2 |
| ECE1 | endothelin converting enzyme 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FH | fumarate hydratase |
| FLT4 | fms-related tyrosine kinase 4 |
| FZD8 | frizzled class receptor 8 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GLG1 | golgi glycoprotein 1 |
| GPR20 | G protein-coupled receptor 20 |
| H1FX | H1 histone family, member X |
| HHLA3 | HERV-H LTR-associating 3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IL17RC | interleukin 17 receptor C |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUN | jun proto-oncogene |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MUC3B | mucin 3B, cell surface associated |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NOTCH4 | notch 4 |
| NRTN | neurturin |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OGDHL | oxoglutarate dehydrogenase-like |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHB13 | protocadherin beta 13 |
| PCDHB3 | protocadherin beta 3 |
| PLCD1 | phospholipase C, delta 1 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RBP4 | retinol binding protein 4, plasma |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNF39 | ring finger protein 39 |
| SIRT5 | sirtuin 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SPHK2 | sphingosine kinase 2 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYT12 | synaptotagmin XII |
| TAGLN2 | transgelin 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMELESS | timeless circadian clock |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM120B | transmembrane protein 120B |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TOP3B | topoisomerase (DNA) III beta |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWF2 | twinfilin actin binding protein 2 |
| UBXN6 | UBX domain protein 6 |
| VASP | vasodilator-stimulated phosphoprotein |
| VWA5A | von Willebrand factor A domain containing 5A |
| WBP2 | WW domain binding protein 2 |
| WDR1 | WD repeat domain 1 |
| ZNF304 | zinc finger protein 304 |
| ZNF506 | zinc finger protein 506 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACTL8 | actin-like 8 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| APOD | apolipoprotein D |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC121 | coiled-coil domain containing 121 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDKN2AIP | CDKN2A interacting protein |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CSF1R | colony stimulating factor 1 receptor |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOC2A | double C2-like domains, alpha |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EMID1 | EMI domain containing 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM204A | family with sequence similarity 204, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FCHSD2 | FCH and double SH3 domains 2 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GHR | growth hormone receptor |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR27 | G protein-coupled receptor 27 |
| HMOX1 | heme oxygenase 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLK5 | kallikrein-related peptidase 5 |
| LINS | lines homolog (Drosophila) |
| LMBR1L | limb development membrane protein 1-like |
| LMNB1 | lamin B1 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MDN1 | MDN1, midasin homolog (yeast) |
| MGC12488 | |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTX1 | neuronal pentraxin I |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSMR | oncostatin M receptor |
| PGBD5 | piggyBac transposable element derived 5 |
| PGR | progesterone receptor |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRAMEF11 | PRAME family member 11 |
| PRPF39 | pre-mRNA processing factor 39 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3D | RAB3D, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNF31 | ring finger protein 31 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SERTAD3 | SERTA domain containing 3 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TDRD1 | tudor domain containing 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRABD | TraB domain containing |
| TRAIP | TRAF interacting protein |
| TRAPPC11 | trafficking protein particle complex 11 |
| TUBA3C | tubulin, alpha 3c |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| WLS | wntless Wnt ligand secretion mediator |
| XAB2 | XPA binding protein 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF480 | zinc finger protein 480 |
| ZNF778 | zinc finger protein 778 |
