| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the amantadine-4222 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif, 8 |
| AFF2 | AF4/FMR2 family, member 2 |
| AGXT | alanine-glyoxylate aminotransferase |
| AIM2 | absent in melanoma 2 |
| ANGPT4 | angiopoietin 4 |
| APOA1 | apolipoprotein A-I |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARSD | arylsulfatase D |
| ASMT | acetylserotonin O-methyltransferase |
| ATP9B | ATPase, class II, type 9B |
| C19ORF26 | chromosome 19 open reading frame 26 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CALML3 | calmodulin-like 3 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFB | complement factor B |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLEC10A | C-type lectin domain family 10, member A |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSN2 | casein beta |
| CXXC4 | CXXC finger protein 4 |
| DACH1 | dachshund family transcription factor 1 |
| DAPK2 | death-associated protein kinase 2 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOC2B | double C2-like domains, beta |
| DOK4 | docking protein 4 |
| EDN3 | endothelin 3 |
| EFS | embryonal Fyn-associated substrate |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| ESPN | espin |
| FAM66D | family with sequence similarity 66, member D |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| FZD10 | frizzled class receptor 10 |
| GLRA2 | glycine receptor, alpha 2 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXB3 | homeobox B3 |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IL37 | interleukin 37 |
| IL5RA | interleukin 5 receptor, alpha |
| INADL | InaD-like (Drosophila) |
| INS | insulin |
| IZUMO4 | IZUMO family member 4 |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KIAA1109 | KIAA1109 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLK13 | kallikrein-related peptidase 13 |
| LARGE | like-glycosyltransferase |
| LUM | lumican |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MC3R | melanocortin 3 receptor |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NRXN2 | neurexin 2 |
| OGFR | opioid growth factor receptor |
| PAPOLB | poly(A) polymerase beta (testis specific) |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| POU6F1 | POU class 6 homeobox 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTTG2 | pituitary tumor-transforming 2 |
| RARA | retinoic acid receptor, alpha |
| REC8 | REC8 meiotic recombination protein |
| REG1A | regenerating islet-derived 1 alpha |
| RSU1 | Ras suppressor protein 1 |
| SCGB2A1 | secretoglobin, family 2A, member 1 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SP110 | SP110 nuclear body protein |
| SPAG11A | sperm associated antigen 11A |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| THEMIS2 | thymocyte selection associated family member 2 |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 |
| TSSK2 | testis-specific serine kinase 2 |
| UBASH3A | ubiquitin associated and SH3 domain containing A |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| AGBL3 | ATP/GTP binding protein-like 3 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANOS1 | anosmin 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOC4 | apolipoprotein C-IV |
| ARRB2 | arrestin, beta 2 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATP13A2 | ATPase type 13A2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BEX1 | brain expressed, X-linked 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CEP131 | centrosomal protein 131kDa |
| CES1 | carboxylesterase 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHMP6 | charged multivesicular body protein 6 |
| CLDN11 | claudin 11 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| ERF | Ets2 repressor factor |
| ETNK2 | ethanolamine kinase 2 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXC1 | forkhead box C1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMPR | guanosine monophosphate reductase |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFNA17 | interferon, alpha 17 |
| IFT54 | intraflagellar transport 54 |
| IL11RA | interleukin 11 receptor, alpha |
| IL17RA | interleukin 17 receptor A |
| IL17RB | interleukin 17 receptor B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA0894 | KIAA0894 protein |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT34 | keratin 34, type I |
| KRT8P12 | keratin 8 pseudogene 12 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LMTK1 | lemur tail kinase 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LTC4S | leukotriene C4 synthase |
| LY86 | lymphocyte antigen 86 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NDP | Norrie disease (pseudoglioma) |
| NMB | neuromedin B |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PALMD | palmdelphin |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE8B | phosphodiesterase 8B |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRDM14 | PR domain containing 14 |
| PRF1 | perforin 1 (pore forming protein) |
| PSKH1 | protein serine kinase H1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SALL2 | spalt-like transcription factor 2 |
| SLN | sarcolipin |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPRYD7 | SPRY domain containing 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TDRD1 | tudor domain containing 1 |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM40 | transmembrane protein 40 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TWISTNB | TWIST neighbor |
| VASH1 | vasohibin 1 |
| VGLL3 | vestigial-like family member 3 |
| ZNF254 | zinc finger protein 254 |
| ZNF492 | zinc finger protein 492 |
| ZNF749 | zinc finger protein 749 |
| ZNF778 | zinc finger protein 778 |
