| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the amantadine-4806 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD28 | CD28 molecule |
| CD70 | CD70 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTNAP2 | contactin associated protein-like 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DBF4B | DBF4 zinc finger B |
| DENND4A | DENN/MADD domain containing 4A |
| DPYS | dihydropyrimidinase |
| DRD2 | dopamine receptor D2 |
| EFNA3 | ephrin-A3 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| EPHB2 | EPH receptor B2 |
| EPOR | erythropoietin receptor |
| ESR1 | estrogen receptor 1 |
| EXOC7 | exocyst complex component 7 |
| EXPH5 | exophilin 5 |
| FAM155A | family with sequence similarity 155, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GALC | galactosylceramidase |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GNRHR | gonadotropin-releasing hormone receptor |
| HOXC5 | homeobox C5 |
| HPGDS | hematopoietic prostaglandin D synthase |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIAA0754 | KIAA0754 |
| KRT24 | keratin 24, type I |
| LATS1 | large tumor suppressor kinase 1 |
| LDAH | lipid droplet associated hydrolase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCL1 | myeloid cell leukemia 1 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MCOLN3 | mucolipin 3 |
| MID1 | midline 1 |
| MIR622 | microRNA 622 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCOA2 | nuclear receptor coactivator 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCNX | pecanex homolog (Drosophila) |
| PGK1 | phosphoglycerate kinase 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PODNL1 | podocan-like 1 |
| PRUNE | prune exopolyphosphatase |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PVRL3 | poliovirus receptor-related 3 |
| R3HDM1 | R3H domain containing 1 |
| RAD51B | RAD51 paralog B |
| RARG | retinoic acid receptor, gamma |
| RGS14 | regulator of G-protein signaling 14 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| S100A8 | S100 calcium binding protein A8 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SIX1 | SIX homeobox 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SMAD5 | SMAD family member 5 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| SQLE | squalene epoxidase |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| ST7 | suppression of tumorigenicity 7 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TMEM242 | transmembrane protein 242 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM23 | tripartite motif containing 23 |
| TSC22D2 | TSC22 domain family, member 2 |
| TUBA3C | tubulin, alpha 3c |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF141 | zinc finger protein 141 |
| ZNF506 | zinc finger protein 506 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTL8 | actin-like 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| APOC4 | apolipoprotein C-IV |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATXN2 | ataxin 2 |
| B9D2 | B9 protein domain 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C5AR2 | complement component 5a receptor 2 |
| C8A | complement component 8, alpha polypeptide |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CASS4 | Cas scaffolding protein family member 4 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CRY2 | cryptochrome circadian clock 2 |
| CSTA | cystatin A (stefin A) |
| CUL9 | cullin 9 |
| CXADR | coxsackie virus and adenovirus receptor |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| DRD1 | dopamine receptor D1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM212B | family with sequence similarity 212, member B |
| FAM46C | family with sequence similarity 46, member C |
| FAM53B | family with sequence similarity 53, member B |
| FBXO2 | F-box protein 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HDAC11 | histone deacetylase 11 |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INO80D | INO80 complex subunit D |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KRT31 | keratin 31, type I |
| LIF | leukemia inhibitory factor |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MITF | microphthalmia-associated transcription factor |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MPI | mannose phosphate isomerase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NAG18 | NAG18 mRNA |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NME5 | NME/NM23 family member 5 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| QSER1 | glutamine and serine rich 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RIN1 | Ras and Rab interactor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPA4 | replication protein A4, 30kDa |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDC3 | syndecan 3 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| TMEM45A | transmembrane protein 45A |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIM25 | tripartite motif containing 25 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC4 | tetratricopeptide repeat domain 4 |
| USP19 | ubiquitin specific peptidase 19 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF394 | zinc finger protein 394 |
| ZNF510 | zinc finger protein 510 |
| ZNF652 | zinc finger protein 652 |
| ZNF750 | zinc finger protein 750 |
