amblyopia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

122 genes co-occuring with the disease amblyopia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PTCH1 patched 1 1.86323
A1CF APOBEC1 complementation factor 1.53436
DSE dermatan sulfate epimerase 1.35115
DPT dermatopontin 1.28217
FBXO7 F-box protein 7 1.21998
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 1.19532
DDT D-dopachrome tautomerase 1.18539
SIRPA signal-regulatory protein alpha 1.16649
KIF21A kinesin family member 21A 1.15453
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 1.14985
FOXL2 forkhead box L2 1.12319
OR2B2 olfactory receptor, family 2, subfamily B, member 2 1.08034
PHOX2A paired-like homeobox 2a 1.05597
SECTM1 secreted and transmembrane 1 1.04882
KRT12 keratin 12, type I 1.03998
CYCS cytochrome c, somatic 1.03451
AXL AXL receptor tyrosine kinase 0.992752
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.979689
CDK13 cyclin-dependent kinase 13 0.906909
VSX1 visual system homeobox 1 0.851992
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.829049
PDLIM1 PDZ and LIM domain 1 0.826999
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.815104
IFITM2 interferon induced transmembrane protein 2 0.811001
HLA-DMA major histocompatibility complex, class II, DM alpha 0.806077
WDFY2 WD repeat and FYVE domain containing 2 0.792951
MBD5 methyl-CpG binding domain protein 5 0.783116
DTNA dystrobrevin, alpha 0.781888
SACK1H scaffolding CK1 anchoring protein H 0.753306
CHN1 chimerin 1 0.750457
POU2F1 POU class 2 homeobox 1 0.74761
LCA5 Leber congenital amaurosis 5 0.733406
NBPF1 neuroblastoma breakpoint family, member 1 0.711587
RTN4R reticulon 4 receptor 0.707157
GRM6 glutamate receptor, metabotropic 6 0.706754
BDNF brain-derived neurotrophic factor 0.683093
WDHD1 WD repeat and HMG-box DNA binding protein 1 0.681894
TUBGCP4 tubulin, gamma complex associated protein 4 0.678701
PAX6 paired box 6 0.653671
GPR17 G protein-coupled receptor 17 0.649718
CRYBB1 crystallin, beta B1 0.627672
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 0.624927
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.618268
CTNNBIP1 catenin, beta interacting protein 1 0.605372
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.58433
GPHN gephyrin 0.581606
TES testin LIM domain protein 0.579661
CTRC chymotrypsin C (caldecrin) 0.577716
CSAD cysteine sulfinic acid decarboxylase 0.571884
TULP1 tubby like protein 1 0.566054
LINGO1 leucine rich repeat and Ig domain containing 1 0.565277
TPBG trophoblast glycoprotein 0.561392
PLCH2 phospholipase C, eta 2 0.551298
SDCBP syndecan binding protein (syntenin) 0.546644
MFRP membrane frizzled-related protein 0.542379
POLK polymerase (DNA directed) kappa 0.535409
KRT3 keratin 3, type II 0.530768
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.528449
CPSF3L cleavage and polyadenylation specific factor 3-like 0.519961
RS1 retinoschisin 1 0.519961
GADD45G growth arrest and DNA-damage-inducible, gamma 0.518805
THEM4 thioesterase superfamily member 4 0.516879
FGFR2 fibroblast growth factor receptor 2 0.51611
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.50689
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.501527
LONP1 lon peptidase 1, mitochondrial 0.499231
NF2 neurofibromin 2 (merlin) 0.498467
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 0.48893
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1 0.477151
PPT1 palmitoyl-protein thioesterase 1 0.476772
BMP2K BMP2 inducible kinase 0.474498
FBLIM1 filamin binding LIM protein 1 0.464283
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.458996
HOXA1 homeobox A1 0.449947
OTX2 orthodenticle homeobox 2 0.449571
LST1 leukocyte specific transcript 1 0.440538
FES FES proto-oncogene, tyrosine kinase 0.427765
MERTK MER proto-oncogene, tyrosine kinase 0.42589
HNMT histamine N-methyltransferase 0.424014
COL4A1 collagen, type IV, alpha 1 0.42364
HPS1 Hermansky-Pudlak syndrome 1 0.421016
CEP290 centrosomal protein 290kDa 0.40904
DAND5 DAN domain family member 5, BMP antagonist 0.406798
SIX3 SIX homeobox 3 0.405305
GREM2 gremlin 2, DAN family BMP antagonist 0.404557
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1 0.400826
LMX1B LIM homeobox transcription factor 1, beta 0.392257
CHD7 chromodomain helicase DNA binding protein 7 0.388909
PER1 period circadian clock 1 0.38111
SNRPN small nuclear ribonucleoprotein polypeptide N 0.380739
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.37555
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.370737
PTH1R parathyroid hormone 1 receptor 0.369628
FOLR1 folate receptor 1 (adult) 0.36704
SALL4 spalt-like transcription factor 4 0.357077
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.355972
A1BG alpha-1-B glycoprotein 0.341639
TKT transketolase 0.332121
NF1 neurofibromin 1 0.316456
GRM1 glutamate receptor, metabotropic 1 0.313189
CRX cone-rod homeobox 0.302337
TCN2 transcobalamin II 0.299452
BEST1 bestrophin 1 0.289386
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.285802
RPGR retinitis pigmentosa GTPase regulator 0.275089
FTO fat mass and obesity associated 0.274021
GALT galactose-1-phosphate uridylyltransferase 0.27153
IDS iduronate 2-sulfatase 0.244345
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.243645
GPANK1 G patch domain and ankyrin repeats 1 0.233183
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.231795
RPE65 retinal pigment epithelium-specific protein 65kDa 0.210253
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.192657
FOS FBJ murine osteosarcoma viral oncogene homolog 0.180084
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.178682
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.172291
FOXP2 forkhead box P2 0.164571
DIABLO diablo, IAP-binding mitochondrial protein 0.159658
OAT ornithine aminotransferase 0.158266
CADM1 cell adhesion molecule 1 0.143773
ATP7B ATPase, Cu++ transporting, beta polypeptide 0.143663
LDLR low density lipoprotein receptor 0.139616