| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the ambroxol-1623 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY9 | adenylate cyclase 9 |
| ADD2 | adducin 2 (beta) |
| AGRN | agrin |
| ARMC6 | armadillo repeat containing 6 |
| ATXN2 | ataxin 2 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CADM3 | cell adhesion molecule 3 |
| CASD1 | CAS1 domain containing 1 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC64 | coiled-coil domain containing 64 |
| CCDC88A | coiled-coil domain containing 88A |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC42 | cell division cycle 42 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLEC1B | C-type lectin domain family 1, member B |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CYB561 | cytochrome b561 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP13 | dual specificity phosphatase 13 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPN2 | epsin 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM153A | family with sequence similarity 153, member A |
| FAM162A | family with sequence similarity 162, member A |
| FH | fumarate hydratase |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GALR3 | galanin receptor 3 |
| GATA2 | GATA binding protein 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLI3 | GLI family zinc finger 3 |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR107 | G protein-coupled receptor 107 |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| ITGA10 | integrin, alpha 10 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MCAM | melanoma cell adhesion molecule |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOSPD2 | motile sperm domain containing 2 |
| MTRF1L | mitochondrial translational release factor 1-like |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NDRG2 | NDRG family member 2 |
| NDRG3 | NDRG family member 3 |
| NMB | neuromedin B |
| NXPH3 | neurexophilin 3 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PADI2 | peptidyl arginine deiminase, type II |
| PADI4 | peptidyl arginine deiminase, type IV |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PLEC | plectin |
| PLIN2 | perilipin 2 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PRDM11 | PR domain containing 11 |
| PRPF6 | pre-mRNA processing factor 6 |
| PRPH | peripherin |
| PRR4 | proline rich 4 (lacrimal) |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTCRA | pre T-cell antigen receptor alpha |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RNASE3 | ribonuclease, RNase A family, 3 |
| RREB1 | ras responsive element binding protein 1 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SEPHS1 | selenophosphate synthetase 1 |
| SH2D1A | SH2 domain containing 1A |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SKAP1 | src kinase associated phosphoprotein 1 |
| SLC17A4 | solute carrier family 17, member 4 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRR | serine racemase |
| STK16 | serine/threonine kinase 16 |
| THY1 | Thy-1 cell surface antigen |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMPRSS5 | transmembrane protease, serine 5 |
| TPI1 | triosephosphate isomerase 1 |
| TRD | T cell receptor delta locus |
| TRIM45 | tripartite motif containing 45 |
| WDR61 | WD repeat domain 61 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF460 | zinc finger protein 460 |
| ZNF507 | zinc finger protein 507 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ABHD3 | abhydrolase domain containing 3 |
| ALG6 | ALG6, alpha-1,3-glucosyltransferase |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| BANP | BTG3 associated nuclear protein |
| BARD1 | BRCA1 associated RING domain 1 |
| BIN2 | bridging integrator 2 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CDK5 | cyclin-dependent kinase 5 |
| CDKN2AIP | CDKN2A interacting protein |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CFAP74 | cilia and flagella associated protein 74 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CORO2A | coronin, actin binding protein, 2A |
| CRY1 | cryptochrome circadian clock 1 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CYC1 | cytochrome c-1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
| ERCC2 | excision repair cross-complementation group 2 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FADS2 | fatty acid desaturase 2 |
| FBRS | fibrosin |
| FBXW4 | F-box and WD repeat domain containing 4 |
| FMNL1 | formin-like 1 |
| FPGS | folylpolyglutamate synthase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GSR | glutathione reductase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HP | haptoglobin |
| HSPA4L | heat shock 70kDa protein 4-like |
| ICAM3 | intercellular adhesion molecule 3 |
| IFITM3 | interferon induced transmembrane protein 3 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase |
| JOSD1 | Josephin domain containing 1 |
| KIAA0753 | KIAA0753 |
| KLHL21 | kelch-like family member 21 |
| LIAS | lipoic acid synthetase |
| LMAN2L | lectin, mannose-binding 2-like |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| LXN | latexin |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| METTL22 | methyltransferase like 22 |
| MGAM | maltase-glucoamylase |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MRPL12 | mitochondrial ribosomal protein L12 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NCAPD2 | non-SMC condensin I complex, subunit D2 |
| NFS1 | NFS1 cysteine desulfurase |
| NOTCH2NL | notch 2 N-terminal like |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| NUP93 | nucleoporin 93kDa |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCTP | phosphatidylcholine transfer protein |
| PHACTR4 | phosphatase and actin regulator 4 |
| PPIEL | peptidylprolyl isomerase E-like pseudogene |
| PUS3 | pseudouridylate synthase 3 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB4B | RAB4B, member RAS oncogene family |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) |
| RNF216 | ring finger protein 216 |
| RNF220 | ring finger protein 220 |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RPS21 | ribosomal protein S21 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAC3D1 | SAC3 domain containing 1 |
| SASH3 | SAM and SH3 domain containing 3 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCPEP1 | serine carboxypeptidase 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC41A3 | solute carrier family 41, member 3 |
| SNX5 | sorting nexin 5 |
| TERT | telomerase reverse transcriptase |
| TESK2 | testis-specific kinase 2 |
| THOC7 | THO complex 7 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TMEM184C | transmembrane protein 184C |
| TRIB1 | tribbles pseudokinase 1 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| UGDH | UDP-glucose 6-dehydrogenase |
| USB1 | U6 snRNA biogenesis 1 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR47 | WD repeat domain 47 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| ZXDC | ZXD family zinc finger C |
