| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ambroxol-5319 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 |
| AHI1 | Abelson helper integration site 1 |
| ANKRD28 | ankyrin repeat domain 28 |
| ATG3 | autophagy related 3 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BMP15 | bone morphogenetic protein 15 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CCPG1 | cell cycle progression 1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDC25C | cell division cycle 25C |
| CIDEB | cell death-inducing DFFA-like effector b |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DPYSL4 | dihydropyrimidinase-like 4 |
| DTNA | dystrobrevin, alpha |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGFR | epidermal growth factor receptor |
| EML3 | echinoderm microtubule associated protein like 3 |
| EP300 | E1A binding protein p300 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM46C | family with sequence similarity 46, member C |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FLII | flightless I homolog (Drosophila) |
| FNDC3A | fibronectin type III domain containing 3A |
| FOXD1 | forkhead box D1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HFE | hemochromatosis |
| HOMER3 | homer scaffolding protein 3 |
| HSF1 | heat shock transcription factor 1 |
| IFT140 | intraflagellar transport 140 |
| IL27RA | interleukin 27 receptor, alpha |
| ING1 | inhibitor of growth family, member 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KDM2A | lysine (K)-specific demethylase 2A |
| KSR1 | kinase suppressor of ras 1 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL7A | methyltransferase like 7A |
| MPPE1 | metallophosphoesterase 1 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NCKAP1 | NCK-associated protein 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| PCDHB3 | protocadherin beta 3 |
| PCNX | pecanex homolog (Drosophila) |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLK4 | polo-like kinase 4 |
| PLXNB1 | plexin B1 |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| RAD17 | RAD17 homolog (S. pombe) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RIOK3 | RIO kinase 3 |
| RND2 | Rho family GTPase 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNW1 | SNW domain containing 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| SYNGR1 | synaptogyrin 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEAD3 | TEA domain family member 3 |
| TEF | thyrotrophic embryonic factor |
| TMEM212 | transmembrane protein 212 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR45 | WD repeat domain 45 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF79 | zinc finger protein 79 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADRA2C | adrenoceptor alpha 2C |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| BBC3 | BCL2 binding component 3 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC186 | coiled-coil domain containing 186 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLSPN | claspin |
| COCH | cochlin |
| COPS7A | COP9 signalosome subunit 7A |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| FANCC | Fanconi anemia, complementation group C |
| FBXO46 | F-box protein 46 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXJ2 | forkhead box J2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| H1F0 | H1 histone family, member 0 |
| HELZ | helicase with zinc finger |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AL | histone cluster 1, H2al |
| HMBOX1 | homeobox containing 1 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF13B | kinesin family member 13B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLK5 | kallikrein-related peptidase 5 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| LAMA3 | laminin, alpha 3 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOSPD3 | motile sperm domain containing 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL17 | mitochondrial ribosomal protein L17 |
| MTCL1 | microtubule crosslinking factor 1 |
| MVP | major vault protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OPHN1 | oligophrenin 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OSMR | oncostatin M receptor |
| PARPBP | PARP1 binding protein |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROCR | protein C receptor, endothelial |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RECQL4 | RecQ protein-like 4 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF146 | ring finger protein 146 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SIK1 | salt-inducible kinase 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| STAG3 | stromal antigen 3 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM184C | transmembrane protein 184C |
| TUBA3C | tubulin, alpha 3c |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| XAB2 | XPA binding protein 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF14 | zinc finger protein 14 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF350 | zinc finger protein 350 |
| ZNF778 | zinc finger protein 778 |