| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the ambroxol-6719 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| CDC14B | cell division cycle 14B |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP290 | centrosomal protein 290kDa |
| CFH | complement factor H |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CISH | cytokine inducible SH2-containing protein |
| CTSF | cathepsin F |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EIF5B | eukaryotic translation initiation factor 5B |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EZR | ezrin |
| FAM63A | family with sequence similarity 63, member A |
| FBXO11 | F-box protein 11 |
| FLJ11292 | |
| GAN | gigaxonin |
| GUK1 | guanylate kinase 1 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| H2AFX | H2A histone family, member X |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIF3A | hypoxia inducible factor 3, alpha subunit |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IFT74 | intraflagellar transport 74 |
| IL12B | interleukin 12B |
| IL20RA | interleukin 20 receptor, alpha |
| IL6 | interleukin 6 |
| INADL | InaD-like (Drosophila) |
| ITGB5 | integrin, beta 5 |
| ITM2B | integral membrane protein 2B |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KDM6A | lysine (K)-specific demethylase 6A |
| KDM6B | lysine (K)-specific demethylase 6B |
| KRT7 | keratin 7, type II |
| LARGE | like-glycosyltransferase |
| LDLR | low density lipoprotein receptor |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LIPG | lipase, endothelial |
| MAK | male germ cell-associated kinase |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MMP3 | matrix metallopeptidase 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTAP | methylthioadenosine phosphorylase |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| PAX2 | paired box 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDS5A | PDS5 cohesin associated factor A |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PRRC2C | proline-rich coiled-coil 2C |
| PRUNE2 | prune homolog 2 (Drosophila) |
| PURA | purine-rich element binding protein A |
| RPL10 | ribosomal protein L10 |
| RPL14 | ribosomal protein L14 |
| RPL27A | ribosomal protein L27a |
| RPL38 | ribosomal protein L38 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
| SERINC5 | serine incorporator 5 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOAT1 | sterol O-acyltransferase 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STK17A | serine/threonine kinase 17a |
| TFG | TRK-fused gene |
| TGFB2 | transforming growth factor, beta 2 |
| TPI1 | triosephosphate isomerase 1 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTF2 | transcription termination factor, RNA polymerase II |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| WBP4 | WW domain binding protein 4 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF214 | zinc finger protein 214 |
| ZNF268 | zinc finger protein 268 |
| ZNF528 | zinc finger protein 528 |
| ZNF623 | zinc finger protein 623 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| AXIN1 | axin 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa |
| CDCA3 | cell division cycle associated 3 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLDN4 | claudin 4 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| DDA1 | DET1 and DDB1 associated 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC2 | excision repair cross-complementation group 2 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GNL1 | guanine nucleotide binding protein-like 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HHLA3 | HERV-H LTR-associating 3 |
| HJURP | Holliday junction recognition protein |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI35 | interferon-induced protein 35 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IPO8 | importin 8 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KLF13 | Kruppel-like factor 13 |
| LRRC61 | leucine rich repeat containing 61 |
| LSM7 | LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MCOLN1 | mucolipin 1 |
| MLF2 | myeloid leukemia factor 2 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRPL23 | mitochondrial ribosomal protein L23 |
| MT1HL1 | metallothionein 1H-like 1 |
| MT2A | metallothionein 2A |
| MXD3 | MAX dimerization protein 3 |
| MYL9 | myosin, light chain 9, regulatory |
| NABP2 | nucleic acid binding protein 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NRSN2 | neurensin 2 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PFN1 | profilin 1 |
| PGD | phosphogluconate dehydrogenase |
| PKM | pyruvate kinase, muscle |
| PKN1 | protein kinase N1 |
| PLD3 | phospholipase D family, member 3 |
| POLM | polymerase (DNA directed), mu |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RABAC1 | Rab acceptor 1 (prenylated) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RPL11 | ribosomal protein L11 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| S100A3 | S100 calcium binding protein A3 |
| S100A4 | S100 calcium binding protein A4 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SF3B5 | splicing factor 3b, subunit 5, 10kDa |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TRIM25 | tripartite motif containing 25 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN1 | tetraspanin 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X |
| WBP2 | WW domain binding protein 2 |
| WDR37 | WD repeat domain 37 |
| ZNF692 | zinc finger protein 692 |
| ZNHIT1 | zinc finger, HIT-type containing 1 |
