amikacin-1618 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the amikacin-1618 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANKRD12 ankyrin repeat domain 12
ANXA6 annexin A6
ARFRP1 ADP-ribosylation factor related protein 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATM ATM serine/threonine kinase
BCAP29 B-cell receptor-associated protein 29
BCLAF1 BCL2-associated transcription factor 1
BST1 bone marrow stromal cell antigen 1
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAST calpastatin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CBX6 chromobox homolog 6
CCNE2 cyclin E2
CD164 CD164 molecule, sialomucin
CHEK1 checkpoint kinase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNPY3 canopy FGF signaling regulator 3
CRCP CGRP receptor component
CSNK1G2 casein kinase 1, gamma 2
CSPP1 centrosome and spindle pole associated protein 1
DCTN4 dynactin 4 (p62)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DERL2 derlin 2
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DPYD dihydropyrimidine dehydrogenase
DUS2 dihydrouridine synthase 2
DUSP2 dual specificity phosphatase 2
E2F1 E2F transcription factor 1
EGR3 early growth response 3
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM153A family with sequence similarity 153, member A
FAM188A family with sequence similarity 188, member A
FASTK Fas-activated serine/threonine kinase
FDX1 ferredoxin 1
FH fumarate hydratase
FRMD8 FERM domain containing 8
GRK6 G protein-coupled receptor kinase 6
HIRA histone cell cycle regulator
HSPA4 heat shock 70kDa protein 4
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IMPAD1 inositol monophosphatase domain containing 1
IVD isovaleryl-CoA dehydrogenase
KPNA4 karyopherin alpha 4 (importin alpha 3)
MAGOH2P mago-nashi homolog 2, pseudogene
MAN1A1 mannosidase, alpha, class 1A, member 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MSH3 mutS homolog 3
MTRF1L mitochondrial translational release factor 1-like
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
PAM peptidylglycine alpha-amidating monooxygenase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
POLI polymerase (DNA directed) iota
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PTBP3 polypyrimidine tract binding protein 3
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAD1 RAD1 checkpoint DNA exonuclease
RAD17 RAD17 homolog (S. pombe)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM3 RNA binding motif (RNP1, RRM) protein 3
RBMS1 RNA binding motif, single stranded interacting protein 1
RECQL4 RecQ protein-like 4
RHOF ras homolog family member F (in filopodia)
RIOK3 RIO kinase 3
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL7 ribosomal protein L7
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae)
SLC25A40 solute carrier family 25, member 40
SLK STE20-like kinase
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMIM7 small integral membrane protein 7
SOD2 superoxide dismutase 2, mitochondrial
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRSF11 serine/arginine-rich splicing factor 11
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THTPA thiamine triphosphatase
TPR translocated promoter region, nuclear basket protein
UBE3A ubiquitin protein ligase E3A
UBQLN4 ubiquilin 4
USF2 upstream transcription factor 2, c-fos interacting
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR82 WD repeat domain 82
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
ZC3H12A zinc finger CCCH-type containing 12A
ZFYVE16 zinc finger, FYVE domain containing 16
ZMYM1 zinc finger, MYM-type 1
ZNF217 zinc finger protein 217
ZNF419 zinc finger protein 419
ZNF443 zinc finger protein 443
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACP2 acid phosphatase 2, lysosomal
AMPD2 adenosine monophosphate deaminase 2
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
APOBR apolipoprotein B receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARMC7 armadillo repeat containing 7
ATAD2B ATPase family, AAA domain containing 2B
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L14 BCL2-like 14 (apoptosis facilitator)
C19ORF40 chromosome 19 open reading frame 40
CAPN15 calpain 15
CD82 CD82 molecule
CER1 cerberus 1, DAN family BMP antagonist
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSNK2A2 casein kinase 2, alpha prime polypeptide
CST3 cystatin C
CYB561D2 cytochrome b561 family, member D2
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
EGR2 early growth response 2
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FMO4 flavin containing monooxygenase 4
GNPDA1 glucosamine-6-phosphate deaminase 1
GSTM1 glutathione S-transferase mu 1
HINFP histone H4 transcription factor
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL4R interleukin 4 receptor
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IRF2 interferon regulatory factor 2
ITPKC inositol-trisphosphate 3-kinase C
KIAA0556 KIAA0556
KIAA0753 KIAA0753
KIF3B kinesin family member 3B
KRCC1 lysine-rich coiled-coil 1
LIMA1 LIM domain and actin binding 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRRC37A3 leucine rich repeat containing 37, member A3
MAD2L1BP MAD2L1 binding protein
MAN2C1 mannosidase, alpha, class 2C, member 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK10 mitogen-activated protein kinase 10
MBIP MAP3K12 binding inhibitory protein 1
MED24 mediator complex subunit 24
METTL1 methyltransferase like 1
METTL22 methyltransferase like 22
MFSD12 major facilitator superfamily domain containing 12
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MUC3A mucin 3A, cell surface associated
NUP93 nucleoporin 93kDa
PAK1IP1 PAK1 interacting protein 1
PANK4 pantothenate kinase 4
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1
PEX26 peroxisomal biogenesis factor 26
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PNPLA6 patatin-like phospholipase domain containing 6
PSKH1 protein serine kinase H1
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB1B RAB1B, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RNH1 ribonuclease/angiogenin inhibitor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP1 ribosomal RNA processing 1
SASH3 SAM and SH3 domain containing 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERTAD3 SERTA domain containing 3
SIRT6 sirtuin 6
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC2A4RG SLC2A4 regulator
SPX spexin hormone
STEAP3 STEAP family member 3, metalloreductase
STXBP2 syntaxin binding protein 2
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TESK2 testis-specific kinase 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM115 transmembrane protein 115
TMEM53 transmembrane protein 53
TPCN1 two pore segment channel 1
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSPAN32 tetraspanin 32
TTC4 tetratricopeptide repeat domain 4
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGDH UDP-glucose 6-dehydrogenase
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast)
USB1 U6 snRNA biogenesis 1
USP6 ubiquitin specific peptidase 6
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR47 WD repeat domain 47
WT1-AS WT1 antisense RNA
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF189 zinc finger protein 189
ZNF692 zinc finger protein 692
ZW10 zw10 kinetochore protein