amikacin-3233 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the amikacin-3233 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM7 ADAM metallopeptidase domain 7
ADGRG2 adhesion G protein-coupled receptor G2
AFAP1 actin filament associated protein 1
AIM1L absent in melanoma 1-like
AKAP5 A kinase (PRKA) anchor protein 5
ALOX5 arachidonate 5-lipoxygenase
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BAAT bile acid CoA:amino acid N-acyltransferase
BAG4 BCL2-associated athanogene 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CA9 carbonic anhydrase IX
CAV2 caveolin 2
CCRL2 chemokine (C-C motif) receptor-like 2
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCA1 chloride channel accessory 1
COL6A1 collagen, type VI, alpha 1
CSNK1G1 casein kinase 1, gamma 1
CTIF CBP80/20-dependent translation initiation factor
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DICER1 dicer 1, ribonuclease type III
DSC3 desmocollin 3
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EPOR erythropoietin receptor
EPS8L1 EPS8-like 1
FAM204A family with sequence similarity 204, member A
FAM224A family with sequence similarity 224, member A (non-protein coding)
FBXL7 F-box and leucine-rich repeat protein 7
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR1 fibroblast growth factor receptor 1
GM2A GM2 ganglioside activator
GRK6 G protein-coupled receptor kinase 6
GRM7 glutamate receptor, metabotropic 7
GRPR gastrin-releasing peptide receptor
HBS1L HBS1-like translational GTPase
HDAC6 histone deacetylase 6
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGHM immunoglobulin heavy constant mu
IL11 interleukin 11
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IMPG2 interphotoreceptor matrix proteoglycan 2
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
JMJD4 jumonji domain containing 4
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRT9 keratin 9, type I
LCMT2 leucine carboxyl methyltransferase 2
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCOLN1 mucolipin 1
MEG3 maternally expressed 3 (non-protein coding)
MMP3 matrix metallopeptidase 3
MSC musculin
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCR3 natural cytotoxicity triggering receptor 3
NFIB nuclear factor I/B
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGDN neuroguidin, EIF4E binding protein
OAZ3 ornithine decarboxylase antizyme 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX4 paired box 4
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PTCRA pre T-cell antigen receptor alpha
PTK2B protein tyrosine kinase 2 beta
RAB3A RAB3A, member RAS oncogene family
RIMS3 regulating synaptic membrane exocytosis 3
SAA4 serum amyloid A4, constitutive
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIGLEC7 sialic acid binding Ig-like lectin 7
STEAP4 STEAP family member 4
SYNJ1 synaptojanin 1
TAPBPL TAP binding protein-like
TBL1Y transducin (beta)-like 1, Y-linked
TBX2 T-box 2
TBXA2R thromboxane A2 receptor
TEF thyrotrophic embryonic factor
TEX40 testis expressed 40
TGM2 transglutaminase 2
TOR4A torsin family 4, member A
TRIM49 tripartite motif containing 49
TSPAN9 tetraspanin 9
UROD uroporphyrinogen decarboxylase
VWA5A von Willebrand factor A domain containing 5A
ZNF442 zinc finger protein 442
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
ARSB arylsulfatase B
ATF3 activating transcription factor 3
BCL9 B-cell CLL/lymphoma 9
C11ORF16 chromosome 11 open reading frame 16
C11ORF30 chromosome 11 open reading frame 30
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC132 coiled-coil domain containing 132
CD79B CD79b molecule, immunoglobulin-associated beta
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIDEC cell death-inducing DFFA-like effector c
CLCN2 chloride channel, voltage-sensitive 2
CRELD1 cysteine-rich with EGF-like domains 1
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
CSTA cystatin A (stefin A)
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CUL9 cullin 9
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FAM186A family with sequence similarity 186, member A
FLJ22184
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAMT guanidinoacetate N-methyltransferase
GIF gastric intrinsic factor (vitamin B synthesis)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPC3 glypican 3
GPR1 G protein-coupled receptor 1
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA0754 KIAA0754
KIF13B kinesin family member 13B
KLK5 kallikrein-related peptidase 5
LAMB3 laminin, beta 3
LONP2 lon peptidase 2, peroxisomal
LRP2 low density lipoprotein receptor-related protein 2
LY6D lymphocyte antigen 6 complex, locus D
LYZ lysozyme
MUC3A mucin 3A, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOL6 nucleolar protein 6 (RNA-associated)
NPFFR1 neuropeptide FF receptor 1
OLFML3 olfactomedin-like 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PALM paralemmin
PCDHB13 protocadherin beta 13
PCDHGB5 protocadherin gamma subfamily B, 5
POMT2 protein-O-mannosyltransferase 2
PRICKLE3 prickle homolog 3 (Drosophila)
QPCTL glutaminyl-peptide cyclotransferase-like
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS20 regulator of G-protein signaling 20
RNF121 ring finger protein 121
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SLC22A14 solute carrier family 22, member 14
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SND1-IT1 SND1 intronic transcript 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TESC tescalcin
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TTC17 tetratricopeptide repeat domain 17
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC119 unc-119 homolog (C. elegans)
UPK2 uroplakin 2
VEZT vezatin, adherens junctions transmembrane protein
VGF VGF nerve growth factor inducible
XAB2 XPA binding protein 2
YIPF3 Yip1 domain family, member 3
ZBTB25 zinc finger and BTB domain containing 25
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF446 zinc finger protein 446