| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the amikacin-5314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ASPH | aspartate beta-hydroxylase |
| BMP5 | bone morphogenetic protein 5 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCND3 | cyclin D3 |
| CDC25C | cell division cycle 25C |
| CENPO | centromere protein O |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CXORF21 | chromosome X open reading frame 21 |
| CYHR1 | cysteine/histidine-rich 1 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DLX4 | distal-less homeobox 4 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTNA | dystrobrevin, alpha |
| EPHA2 | EPH receptor A2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FEM1B | fem-1 homolog b (C. elegans) |
| FH | fumarate hydratase |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GFER | growth factor, augmenter of liver regeneration |
| GLS | glutaminase |
| GRK5 | G protein-coupled receptor kinase 5 |
| HLA-G | major histocompatibility complex, class I, G |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IL22 | interleukin 22 |
| KLF6 | Kruppel-like factor 6 |
| LRRC20 | leucine rich repeat containing 20 |
| MAP4 | microtubule-associated protein 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MZF1 | myeloid zinc finger 1 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCNX | pecanex homolog (Drosophila) |
| PDCL | phosducin-like |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLXND1 | plexin D1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PSPH | phosphoserine phosphatase |
| PTRF | polymerase I and transcript release factor |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RANBP1 | RAN binding protein 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RNF2 | ring finger protein 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| RPL10 | ribosomal protein L10 |
| RPL26 | ribosomal protein L26 |
| S100A6 | S100 calcium binding protein A6 |
| SENP5 | SUMO1/sentrin specific peptidase 5 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SGSM3 | small G protein signaling modulator 3 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SNW1 | SNW domain containing 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| SRPX | sushi-repeat containing protein, X-linked |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK17A | serine/threonine kinase 17a |
| STK38L | serine/threonine kinase 38 like |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEAD3 | TEA domain family member 3 |
| TFE3 | transcription factor binding to IGHM enhancer 3 |
| TMEM63A | transmembrane protein 63A |
| TTC9 | tetratricopeptide repeat domain 9 |
| TUBA3D | tubulin, alpha 3d |
| UBOX5 | U-box domain containing 5 |
| UBQLN4 | ubiquilin 4 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| WDR1 | WD repeat domain 1 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| YIPF6 | Yip1 domain family, member 6 |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF518A | zinc finger protein 518A |
| ZNF701 | zinc finger protein 701 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABHD4 | abhydrolase domain containing 4 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX7 | chromobox homolog 7 |
| CCDC170 | coiled-coil domain containing 170 |
| CCNT1 | cyclin T1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| COL9A2 | collagen, type IX, alpha 2 |
| COPS7B | COP9 signalosome subunit 7B |
| CORO1A | coronin, actin binding protein, 1A |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAM155B | family with sequence similarity 155, member B |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FGGY | FGGY carbohydrate kinase domain containing |
| GAR1 | GAR1 ribonucleoprotein |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GTPBP6 | GTP binding protein 6 (putative) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HYOU1 | hypoxia up-regulated 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ILK | integrin-linked kinase |
| JRKL | JRK-like |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LOXL1 | lysyl oxidase-like 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL4 | methyltransferase like 4 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MPDZ | multiple PDZ domain protein |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NOTCH1 | notch 1 |
| NVL | nuclear VCP-like |
| ODF2 | outer dense fiber of sperm tails 2 |
| OPN3 | opsin 3 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 |
| PCID2 | PCI domain containing 2 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLD3 | phospholipase D family, member 3 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROS1 | protein S (alpha) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RECQL4 | RecQ protein-like 4 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF187 | ring finger protein 187 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SCAI | suppressor of cancer cell invasion |
| SDF2 | stromal cell-derived factor 2 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| STRN4 | striatin, calmodulin binding protein 4 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TCTN1 | tectonic family member 1 |
| TLN1 | talin 1 |
| TMEM62 | transmembrane protein 62 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| XAB2 | XPA binding protein 2 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF211 | zinc finger protein 211 |
| ZNF266 | zinc finger protein 266 |
| ZNF665 | zinc finger protein 665 |
| ZNF7 | zinc finger protein 7 |