| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the aminocaproic acid-7258 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATXN2L | ataxin 2-like |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA11 | carbonic anhydrase XI |
| CABIN1 | calcineurin binding protein 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CAV2 | caveolin 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLDN11 | claudin 11 |
| COL6A1 | collagen, type VI, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DNPEP | aspartyl aminopeptidase |
| DSPP | dentin sialophosphoprotein |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HABP4 | hyaluronan binding protein 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INSR | insulin receptor |
| IRF1 | interferon regulatory factor 1 |
| KIF5C | kinesin family member 5C |
| KLHL22 | kelch-like family member 22 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAP7 | microtubule-associated protein 7 |
| MARS | methionyl-tRNA synthetase |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MLH3 | mutL homolog 3 |
| MTSS1L | metastasis suppressor 1-like |
| MUC1 | mucin 1, cell surface associated |
| MYH15 | myosin, heavy chain 15 |
| MYO9B | myosin IXB |
| MYRF | myelin regulatory factor |
| N4BP1 | NEDD4 binding protein 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NID2 | nidogen 2 (osteonidogen) |
| NOTCH3 | notch 3 |
| NRXN3 | neurexin 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PALM | paralemmin |
| PLA2G15 | phospholipase A2, group XV |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RPGRIP1L | RPGRIP1-like |
| RREB1 | ras responsive element binding protein 1 |
| RUNX3 | runt-related transcription factor 3 |
| RWDD2A | RWD domain containing 2A |
| SCARB1 | scavenger receptor class B, member 1 |
| SFTPB | surfactant protein B |
| SGSM3 | small G protein signaling modulator 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SKIL | SKI-like proto-oncogene |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBC1D5 | TBC1 domain family, member 5 |
| TMEM231 | transmembrane protein 231 |
| TNC | tenascin C |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| UNC45A | unc-45 homolog A (C. elegans) |
| UROD | uroporphyrinogen decarboxylase |
| USP20 | ubiquitin specific peptidase 20 |
| VCAN | versican |
| WWOX | WW domain containing oxidoreductase |
| ZNF408 | zinc finger protein 408 |
| ZNF675 | zinc finger protein 675 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CAPN5 | calpain 5 |
| CLEC16A | C-type lectin domain family 16, member A |
| CTAGE9 | CTAGE family, member 9 |
| CTNNBL1 | catenin, beta like 1 |
| CUL9 | cullin 9 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DTWD1 | DTW domain containing 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ERAL1 | Era-like 12S mitochondrial rRNA chaperone 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC5 | exocyst complex component 5 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM172A | family with sequence similarity 172, member A |
| FAM179B | family with sequence similarity 179, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO46 | F-box protein 46 |
| GAB2 | GRB2-associated binding protein 2 |
| GPHN | gephyrin |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIRA | histone cell cycle regulator |
| HIST1H2AG | histone cluster 1, H2ag |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IL7R | interleukin 7 receptor |
| ISL1 | ISL LIM homeobox 1 |
| JUNB | jun B proto-oncogene |
| KIAA1462 | KIAA1462 |
| KPTN | kaptin (actin binding protein) |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC49 | leucine rich repeat containing 49 |
| MAN2B2 | mannosidase, alpha, class 2B, member 2 |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MTMR11 | myotubularin related protein 11 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NAP1L3 | nucleosome assembly protein 1-like 3 |
| NMB | neuromedin B |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RBL1 | retinoblastoma-like 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RCOR3 | REST corepressor 3 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNF121 | ring finger protein 121 |
| RNF170 | ring finger protein 170 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERINC5 | serine incorporator 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNX24 | sorting nexin 24 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TASP1 | taspase, threonine aspartase, 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBL3 | transducin (beta)-like 3 |
| TGDS | TDP-glucose 4,6-dehydratase |
| TMEM177 | transmembrane protein 177 |
| TMEM38B | transmembrane protein 38B |
| TNS2 | tensin 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TTF2 | transcription termination factor, RNA polymerase II |
| TTI2 | TELO2 interacting protein 2 |
| TULP4 | tubby like protein 4 |
| USB1 | U6 snRNA biogenesis 1 |
| USPL1 | ubiquitin specific peptidase like 1 |
| YEATS4 | YEATS domain containing 4 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF107 | zinc finger protein 107 |
| ZNF232 | zinc finger protein 232 |
| ZNF562 | zinc finger protein 562 |
| ZNF862 | zinc finger protein 862 |
