aminohippuric acid-3076 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the aminohippuric acid-3076 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMH anti-Mullerian hormone
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATG10 autophagy related 10
AXIN1 axin 1
BCAS1 breast carcinoma amplified sequence 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BLNK B-cell linker
BMP7 bone morphogenetic protein 7
BRS3 bombesin-like receptor 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD59 CD59 molecule, complement regulatory protein
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLDN17 claudin 17
CLEC1B C-type lectin domain family 1, member B
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL10A1 collagen, type X, alpha 1
COPE coatomer protein complex, subunit epsilon
CPA4 carboxypeptidase A4
CTIF CBP80/20-dependent translation initiation factor
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DVL2 dishevelled segment polarity protein 2
EDIL3 EGF-like repeats and discoidin I-like domains 3
ETV7 ets variant 7
FER fer (fps/fes related) tyrosine kinase
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFBP1 fibroblast growth factor binding protein 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GOSR2 golgi SNAP receptor complex member 2
GPC1 glypican 1
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC10 homeobox C10
HOXC8 homeobox C8
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICAM5 intercellular adhesion molecule 5, telencephalin
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
INA internexin neuronal intermediate filament protein, alpha
IQCK IQ motif containing K
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT8 keratin 8, type II
KRT81 keratin 81, type II
LOX lysyl oxidase
LRRC1 leucine rich repeat containing 1
MAP4 microtubule-associated protein 4
MAST2 microtubule associated serine/threonine kinase 2
MCC mutated in colorectal cancers
MCM3AP minichromosome maintenance complex component 3 associated protein
MFAP3L microfibrillar-associated protein 3-like
MID2 midline 2
MUC4 mucin 4, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NKX3-1 NK3 homeobox 1
NPR2 natriuretic peptide receptor 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
PADI1 peptidyl arginine deiminase, type I
PADI4 peptidyl arginine deiminase, type IV
PALLD palladin, cytoskeletal associated protein
PEG3 paternally expressed 3
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRJ protein tyrosine phosphatase, receptor type, J
PYY peptide YY
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB33A RAB33A, member RAS oncogene family
RASAL2 RAS protein activator like 2
REPS2 RALBP1 associated Eps domain containing 2
REST RE1-silencing transcription factor
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SARDH sarcosine dehydrogenase
TCEAL2 transcription elongation factor A (SII)-like 2
TCP11L1 t-complex 11, testis-specific-like 1
TMC7 transmembrane channel-like 7
TPH1 tryptophan hydroxylase 1
TRIM10 tripartite motif containing 10
TULP2 tubby like protein 2
TYMP thymidine phosphorylase
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VSX1 visual system homeobox 1
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
ZIC3 Zic family member 3
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ADM adrenomedullin
AGBL5 ATP/GTP binding protein-like 5
AMPD2 adenosine monophosphate deaminase 2
ANXA3 annexin A3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARHGAP4 Rho GTPase activating protein 4
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC6 armadillo repeat containing 6
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCL7A B-cell CLL/lymphoma 7A
BEX1 brain expressed, X-linked 1
C9ORF40 chromosome 9 open reading frame 40
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNJ cyclin J
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPT centromere protein T
CHML choroideremia-like (Rab escort protein 2)
CHMP7 charged multivesicular body protein 7
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLEC16A C-type lectin domain family 16, member A
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CORO7 coronin 7
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYL1 crystallin, lambda 1
CTSD cathepsin D
DEPDC5 DEP domain containing 5
DGKE diacylglycerol kinase, epsilon 64kDa
DHRS7B dehydrogenase/reductase (SDR family) member 7B
FAM160B2 family with sequence similarity 160, member B2
FAM184A family with sequence similarity 184, member A
FAM57A family with sequence similarity 57, member A
FBXL15 F-box and leucine-rich repeat protein 15
FEM1C fem-1 homolog c (C. elegans)
G6PD glucose-6-phosphate dehydrogenase
GPR85 G protein-coupled receptor 85
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1B histone cluster 1, H1b
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
HK1 hexokinase 1
IDI2-AS1 IDI2 antisense RNA 1
IL12B interleukin 12B
IL4R interleukin 4 receptor
IQCG IQ motif containing G
ITGA10 integrin, alpha 10
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JUNB jun B proto-oncogene
KIAA0319L KIAA0319-like
LHFP lipoma HMGIC fusion partner
LINC00339 long intergenic non-protein coding RNA 339
LRP3 low density lipoprotein receptor-related protein 3
LRRC41 leucine rich repeat containing 41
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MTCP1 mature T-cell proliferation 1
MYNN myoneurin
NABP2 nucleic acid binding protein 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NUPR1 nuclear protein, transcriptional regulator, 1
PARP11 poly (ADP-ribose) polymerase family, member 11
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX2 paired-like homeodomain 2
PROS1 protein S (alpha)
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RNF121 ring finger protein 121
RNF122 ring finger protein 122
RPP25 ribonuclease P/MRP 25kDa subunit
SERGEF secretion regulating guanine nucleotide exchange factor
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SP1 Sp1 transcription factor
SP140 SP140 nuclear body protein
SPON2 spondin 2, extracellular matrix protein
SSBP3 single stranded DNA binding protein 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLR8 toll-like receptor 8
TMC5 transmembrane channel-like 5
TMEM110 transmembrane protein 110
UNC93B1 unc-93 homolog B1 (C. elegans)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR33 WD repeat domain 33
WDR46 WD repeat domain 46
ZNF215 zinc finger protein 215
ZNF428 zinc finger protein 428
ZNF480 zinc finger protein 480
ZNF862 zinc finger protein 862
ZSCAN16 zinc finger and SCAN domain containing 16