aminohippuric acid-6294 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the aminohippuric acid-6294 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
AIM1L absent in melanoma 1-like
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARTN artemin
ASIC2 acid sensing (proton gated) ion channel 2
C5ORF42 chromosome 5 open reading frame 42
C9ORF156 chromosome 9 open reading frame 156
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD33 CD33 molecule
CDK6 cyclin-dependent kinase 6
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CFAP45 cilia and flagella associated protein 45
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRYGC crystallin, gamma C
CUL9 cullin 9
DBP D site of albumin promoter (albumin D-box) binding protein
DCT dopachrome tautomerase
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOCK10 dedicator of cytokinesis 10
DRD2 dopamine receptor D2
DSTYK dual serine/threonine and tyrosine protein kinase
EMID1 EMI domain containing 1
FGF18 fibroblast growth factor 18
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GOLGA2 golgin A2
GP6 glycoprotein VI (platelet)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HN1L hematological and neurological expressed 1-like
ICAM1 intercellular adhesion molecule 1
IL11 interleukin 11
IL12RB1 interleukin 12 receptor, beta 1
ITGB7 integrin, beta 7
KHSRP KH-type splicing regulatory protein
KIAA1024 KIAA1024
KIF1A kinesin family member 1A
KIF26B kinesin family member 26B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT15 keratin 15, type I
KYNU kynureninase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPAR4 lysophosphatidic acid receptor 4
LRRC61 leucine rich repeat containing 61
LRRC75B leucine rich repeat containing 75B
MAP2K7 mitogen-activated protein kinase kinase 7
MBP myelin basic protein
MFSD6 major facilitator superfamily domain containing 6
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYH15 myosin, heavy chain 15
NOVA1 neuro-oncological ventral antigen 1
NT5M 5',3'-nucleotidase, mitochondrial
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAPPA2 pappalysin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH11Y protocadherin 11 Y-linked
PDE8B phosphodiesterase 8B
PER2 period circadian clock 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLIN2 perilipin 2
PLXNC1 plexin C1
POLL polymerase (DNA directed), lambda
PROL1 proline rich, lacrimal 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11B RAB11B, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOT2 ras homolog family member T2
RNF6 ring finger protein (C3H2C3 type) 6
RRAGB Ras-related GTP binding B
RYR2 ryanodine receptor 2 (cardiac)
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC38A7 solute carrier family 38, member 7
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX17 SRY (sex determining region Y)-box 17
SPATA1 spermatogenesis associated 1
SPTBN2 spectrin, beta, non-erythrocytic 2
SRPX2 sushi-repeat containing protein, X-linked 2
STON1 stonin 1
TAAR5 trace amine associated receptor 5
TFDP3 transcription factor Dp family, member 3
TK2 thymidine kinase 2, mitochondrial
TLN2 talin 2
TRA T cell receptor alpha locus
TRAF3IP2 TRAF3 interacting protein 2
TRIM62 tripartite motif containing 62
UBXN1 UBX domain protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WNT5B wingless-type MMTV integration site family, member 5B
ZFPL1 zinc finger protein-like 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABHD8 abhydrolase domain containing 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANKRD36 ankyrin repeat domain 36
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BEX1 brain expressed, X-linked 1
BLMH bleomycin hydrolase
CCDC69 coiled-coil domain containing 69
CCDC94 coiled-coil domain containing 94
CCND3 cyclin D3
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP85 centrosomal protein 85kDa
CHKB choline kinase beta
CHMP1A charged multivesicular body protein 1A
CRYBA2 crystallin, beta A2
CTSO cathepsin O
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DOLK dolichol kinase
DRAM1 DNA-damage regulated autophagy modulator 1
DYSF dysferlin
ECM1 extracellular matrix protein 1
EFNA1 ephrin-A1
EVPL envoplakin
FAM53B family with sequence similarity 53, member B
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK2 galactokinase 2
GLDC glycine dehydrogenase (decarboxylating)
GLT8D2 glycosyltransferase 8 domain containing 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HCG4 HLA complex group 4 (non-protein coding)
HDAC5 histone deacetylase 5
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLX H2.0-like homeobox
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IGFLR1 IGF-like family receptor 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KDM4D lysine (K)-specific demethylase 4D
KRT6A keratin 6A, type II
LSR lipolysis stimulated lipoprotein receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAGEF1 melanoma antigen family F1
MCRS1 microspherule protein 1
MN1 meningioma (disrupted in balanced translocation) 1
MRPL28 mitochondrial ribosomal protein L28
MUC3B mucin 3B, cell surface associated
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NMB neuromedin B
NNT nicotinamide nucleotide transhydrogenase
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCBP4 poly(rC) binding protein 4
PDE12 phosphodiesterase 12
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PMPCA peptidase (mitochondrial processing) alpha
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PSKH1 protein serine kinase H1
RUVBL1 RuvB-like AAA ATPase 1
SCRN3 secernin 3
SETD6 SET domain containing 6
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SND1-IT1 SND1 intronic transcript 1
SNX16 sorting nexin 16
STBD1 starch binding domain 1
STX5 syntaxin 5
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TMEM2 transmembrane protein 2
TMEM57 transmembrane protein 57
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAPPC6A trafficking protein particle complex 6A
XAB2 XPA binding protein 2
XYLT2 xylosyltransferase II
ZNF197 zinc finger protein 197
ZNF385D zinc finger protein 385D
ZNF442 zinc finger protein 442
ZNF552 zinc finger protein 552
ZNF629 zinc finger protein 629
ZNF671 zinc finger protein 671
ZNHIT2 zinc finger, HIT-type containing 2