aminohippuric acid-6453 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the aminohippuric acid-6453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AJAP1 adherens junctions associated protein 1
AKAP4 A kinase (PRKA) anchor protein 4
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARNT aryl hydrocarbon receptor nuclear translocator
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
C1ORF105 chromosome 1 open reading frame 105
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAV2 caveolin 2
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CES3 carboxylesterase 3
CLCN7 chloride channel, voltage-sensitive 7
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL6A2 collagen, type VI, alpha 2
COMT catechol-O-methyltransferase
CRELD1 cysteine-rich with EGF-like domains 1
CST1 cystatin SN
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCAF11 DDB1 and CUL4 associated factor 11
DFNB31 deafness, autosomal recessive 31
DLC1 DLC1 Rho GTPase activating protein
DMPK dystrophia myotonica-protein kinase
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSC3 desmocollin 3
EFNB3 ephrin-B3
GLP1R glucagon-like peptide 1 receptor
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXD9 homeobox D9
IFT140 intraflagellar transport 140
IHH indian hedgehog
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT17 keratin 17, type I
KRT9 keratin 9, type I
LIN7A lin-7 homolog A (C. elegans)
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
LRRC48 leucine rich repeat containing 48
LRRC75B leucine rich repeat containing 75B
MAP2K2 mitogen-activated protein kinase kinase 2
MEFV Mediterranean fever
MIER2 mesoderm induction early response 1, family member 2
MMRN2 multimerin 2
MSI1 musashi RNA-binding protein 1
MTA1 metastasis associated 1
MYBPC3 myosin binding protein C, cardiac
N4BP2L1 NEDD4 binding protein 2-like 1
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOV nephroblastoma overexpressed
NR0B1 nuclear receptor subfamily 0, group B, member 1
NUP88 nucleoporin 88kDa
ONECUT2 one cut homeobox 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PLCL2 phospholipase C-like 2
PQLC2 PQ loop repeat containing 2
PSG9 pregnancy specific beta-1-glycoprotein 9
PTP4A3 protein tyrosine phosphatase type IVA, member 3
QKI QKI, KH domain containing, RNA binding
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RBM12B-AS1 RBM12B antisense RNA 1
RCAN2 regulator of calcineurin 2
S100A11 S100 calcium binding protein A11
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIX1 SIX homeobox 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SND1-IT1 SND1 intronic transcript 1
SOD3 superoxide dismutase 3, extracellular
SRSF1 serine/arginine-rich splicing factor 1
SS18 synovial sarcoma translocation, chromosome 18
STXBP5L syntaxin binding protein 5-like
SYCE1L synaptonemal complex central element protein 1-like
TBX5 T-box 5
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPMT thiopurine S-methyltransferase
TRIM36 tripartite motif containing 36
TSC22D2 TSC22 domain family, member 2
TSC22D4 TSC22 domain family, member 4
ULK2 unc-51 like autophagy activating kinase 2
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
UTRN utrophin
VAC14 Vac14 homolog (S. cerevisiae)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR78 WD repeat domain 78
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
ARC activity-regulated cytoskeleton-associated protein
ARR3 arrestin 3, retinal (X-arrestin)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAIAP3 BAI1-associated protein 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
C1ORF21 chromosome 1 open reading frame 21
CCDC85C coiled-coil domain containing 85C
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CEP85 centrosomal protein 85kDa
CLIC2 chloride intracellular channel 2
CORO7 coronin 7
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRIP1 cysteine-rich protein 1 (intestinal)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTNNBL1 catenin, beta like 1
CXADR coxsackie virus and adenovirus receptor
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ELP3 elongator acetyltransferase complex subunit 3
EPHA2 EPH receptor A2
FAM86C1 family with sequence similarity 86, member C1
FBXL2 F-box and leucine-rich repeat protein 2
FGL1 fibrinogen-like 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HOXC5 homeobox C5
HP1BP3 heterochromatin protein 1, binding protein 3
HYAL2 hyaluronoglucosaminidase 2
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KLHL28 kelch-like family member 28
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00597 long intergenic non-protein coding RNA 597
LMO2 LIM domain only 2 (rhombotin-like 1)
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MBTD1 mbt domain containing 1
MFAP2 microfibrillar-associated protein 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL2 NEL-like 2 (chicken)
NPFFR1 neuropeptide FF receptor 1
NPY5R neuropeptide Y receptor Y5
NT5DC3 5'-nucleotidase domain containing 3
ODF2 outer dense fiber of sperm tails 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PGPEP1 pyroglutamyl-peptidase I
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLD2 phospholipase D2
PMCH pro-melanin-concentrating hormone
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POLL polymerase (DNA directed), lambda
PRDM14 PR domain containing 14
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PROL1 proline rich, lacrimal 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPSN receptor-associated protein of the synapse
RNF208 ring finger protein 208
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC17A2 solute carrier family 17, member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SREK1IP1 SREK1-interacting protein 1
STRA6 stimulated by retinoic acid 6
SYNC syncoilin, intermediate filament protein
TBC1D2 TBC1 domain family, member 2
TMPRSS4 transmembrane protease, serine 4
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPAN1 tetraspanin 1
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
URM1 ubiquitin related modifier 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZSCAN31 zinc finger and SCAN domain containing 31