aminophenazone-2222 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the aminophenazone-2222 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADAM12 ADAM metallopeptidase domain 12
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGMAT agmatine ureohydrolase (agmatinase)
ALLC allantoicase
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
BEST2 bestrophin 2
C19ORF66 chromosome 19 open reading frame 66
CADM4 cell adhesion molecule 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CCL13 chemokine (C-C motif) ligand 13
CD1E CD1e molecule
CD22 CD22 molecule
CD53 CD53 molecule
CDHR2 cadherin-related family member 2
CDK6 cyclin-dependent kinase 6
CFI complement factor I
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC2D C-type lectin domain family 2, member D
CLEC4E C-type lectin domain family 4, member E
COL6A1 collagen, type VI, alpha 1
CRYGD crystallin, gamma D
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DBF4B DBF4 zinc finger B
DLC1 DLC1 Rho GTPase activating protein
DMBT1 deleted in malignant brain tumors 1
EMX1 empty spiracles homeobox 1
FAM171A1 family with sequence similarity 171, member A1
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FN1 fibronectin 1
FRMD1 FERM domain containing 1
FST follistatin
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GPM6A glycoprotein M6A
HBEGF heparin-binding EGF-like growth factor
HDAC7 histone deacetylase 7
HDC histidine decarboxylase
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXB2 homeobox B2
HOXD1 homeobox D1
IBSP integrin-binding sialoprotein
IFNA17 interferon, alpha 17
INHBE inhibin, beta E
IRF8 interferon regulatory factor 8
KIAA0125 KIAA0125
KLHL29 kelch-like family member 29
LRP12 low density lipoprotein receptor-related protein 12
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MKL1 megakaryoblastic leukemia (translocation) 1
MPZ myelin protein zero
MUC5B mucin 5B, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NELL2 NEL-like 2 (chicken)
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NRL neural retina leucine zipper
PARP3 poly (ADP-ribose) polymerase family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R37 protein phosphatase 1, regulatory subunit 37
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBMS2 RNA binding motif, single stranded interacting protein 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF122 ring finger protein 122
S100A8 S100 calcium binding protein A8
SAMD4A sterile alpha motif domain containing 4A
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEC24D SEC24 family member D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SIGLEC6 sialic acid binding Ig-like lectin 6
SKIL SKI-like proto-oncogene
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SORBS1 sorbin and SH3 domain containing 1
SPRY2 sprouty homolog 2 (Drosophila)
SPTBN5 spectrin, beta, non-erythrocytic 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAOK2 TAO kinase 2
TBC1D2 TBC1 domain family, member 2
TBXA2R thromboxane A2 receptor
THRB thyroid hormone receptor, beta
TLK1 tousled-like kinase 1
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM242 transmembrane protein 242
TRPC1 transient receptor potential cation channel, subfamily C, member 1
UBQLN4 ubiquilin 4
USP12 ubiquitin specific peptidase 12
WDFY3 WD repeat and FYVE domain containing 3
WNK1 WNK lysine deficient protein kinase 1
WNT16 wingless-type MMTV integration site family, member 16
ZFHX2 zinc finger homeobox 2

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE5 adhesion G protein-coupled receptor E5
AFAP1 actin filament associated protein 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARC activity-regulated cytoskeleton-associated protein
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCDC85C coiled-coil domain containing 85C
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYB5R1 cytochrome b5 reductase 1
DMTN dematin actin binding protein
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHX2 epoxide hydrolase 2, cytoplasmic
ESRP2 epithelial splicing regulatory protein 2
ETNK2 ethanolamine kinase 2
EXOSC9 exosome component 9
FBXL7 F-box and leucine-rich repeat protein 7
FLJ22184
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AJ histone cluster 1, H2aj
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT54 intraflagellar transport 54
IGSF1 immunoglobulin superfamily, member 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
LAMP3 lysosomal-associated membrane protein 3
LHX6 LIM homeobox 6
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP5 low density lipoprotein receptor-related protein 5
MAST3 microtubule associated serine/threonine kinase 3
MON1B MON1 secretory trafficking family member B
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYOZ1 myozenin 1
NPTX1 neuronal pentraxin I
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
PAIP2B poly(A) binding protein interacting protein 2B
PEX26 peroxisomal biogenesis factor 26
PHC1 polyhomeotic homolog 1 (Drosophila)
PICK1 protein interacting with PRKCA 1
PLAC1 placenta-specific 1
PPT2 palmitoyl-protein thioesterase 2
PRR7 proline rich 7 (synaptic)
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF121 ring finger protein 121
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN1B sodium channel, voltage gated, type I beta subunit
SEC14L5 SEC14-like 5 (S. cerevisiae)
SECTM1 secreted and transmembrane 1
SIPA1 signal-induced proliferation-associated 1
SLC12A9 solute carrier family 12, member 9
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLMO1 slowmo homolog 1 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPON2 spondin 2, extracellular matrix protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TLN1 talin 1
TMEM120B transmembrane protein 120B
TMEM53 transmembrane protein 53
TRIM21 tripartite motif containing 21
TSPAN15 tetraspanin 15
TUBA3C tubulin, alpha 3c
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WFDC2 WAP four-disulfide core domain 2
XYLT2 xylosyltransferase II
YBX2 Y box binding protein 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF204P zinc finger protein 204, pseudogene
ZNF668 zinc finger protein 668