aminophenazone-4481 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the aminophenazone-4481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APAF1 apoptotic peptidase activating factor 1
AQP4 aquaporin 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BATF3 basic leucine zipper transcription factor, ATF-like 3
BLVRA biliverdin reductase A
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD34 CD34 molecule
CDK18 cyclin-dependent kinase 18
CETN1 centrin, EF-hand protein, 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CNTFR ciliary neurotrophic factor receptor
COL11A2 collagen, type XI, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTIF CBP80/20-dependent translation initiation factor
CUL3 cullin 3
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DZIP1 DAZ interacting zinc finger protein 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FBLN1 fibulin 1
FLJ21369 uncharacterized protein FLJ21369
FPR1 formyl peptide receptor 1
GAB1 GRB2-associated binding protein 1
GHRHR growth hormone releasing hormone receptor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLP1R glucagon-like peptide 1 receptor
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPATCH4 G patch domain containing 4
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GREB1L growth regulation by estrogen in breast cancer-like
HSPG2 heparan sulfate proteoglycan 2
ICOSLG inducible T-cell co-stimulator ligand
IL10 interleukin 10
INA internexin neuronal intermediate filament protein, alpha
ITGA8 integrin, alpha 8
KAT2A K(lysine) acetyltransferase 2A
KCTD14 potassium channel tetramerization domain containing 14
KIAA0319L KIAA0319-like
KIF1C kinesin family member 1C
KLHL4 kelch-like family member 4
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT7 keratin 7, type II
LAMC3 laminin, gamma 3
LGALS8 lectin, galactoside-binding, soluble, 8
LIME1 Lck interacting transmembrane adaptor 1
LINC00312 long intergenic non-protein coding RNA 312
MCF2L MCF.2 cell line derived transforming sequence-like
MFAP3L microfibrillar-associated protein 3-like
MFGE8 milk fat globule-EGF factor 8 protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MINK1 misshapen-like kinase 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MORN1 MORN repeat containing 1
NCAM2 neural cell adhesion molecule 2
NELL2 NEL-like 2 (chicken)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NPR1 natriuretic peptide receptor 1
NRF1 nuclear respiratory factor 1
PAOX polyamine oxidase (exo-N4-amino)
PAPPA2 pappalysin 2
PEX5L peroxisomal biogenesis factor 5-like
PLXNB1 plexin B1
PRDM12 PR domain containing 12
PSG6 pregnancy specific beta-1-glycoprotein 6
RAB40A RAB40A, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RECQL5 RecQ protein-like 5
REEP1 receptor accessory protein 1
RFPL1 ret finger protein-like 1
RFPL2 ret finger protein-like 2
RNF208 ring finger protein 208
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
SLC16A6 solute carrier family 16, member 6
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPON1 spondin 1, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SREBF2 sterol regulatory element binding transcription factor 2
TACR1 tachykinin receptor 1
TET3 tet methylcytosine dioxygenase 3
TMEM246 transmembrane protein 246
TMPRSS6 transmembrane protease, serine 6
WDR78 WD repeat domain 78
ZBED4 zinc finger, BED-type containing 4
ZFP64 ZFP64 zinc finger protein
ZFPM2 zinc finger protein, FOG family member 2
ZHX3 zinc fingers and homeoboxes 3
ZMYND8 zinc finger, MYND-type containing 8
ZSCAN2 zinc finger and SCAN domain containing 2

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
AFAP1 actin filament associated protein 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARL15 ADP-ribosylation factor-like 15
ARSJ arylsulfatase family, member J
ASAP1-IT1 ASAP1 intronic transcript 1
ASB7 ankyrin repeat and SOCS box containing 7
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BCAS3 breast carcinoma amplified sequence 3
BEX1 brain expressed, X-linked 1
BEX4 brain expressed, X-linked 4
BICC1 BicC family RNA binding protein 1
BTC betacellulin
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF93 chromosome 14 open reading frame 93
C17ORF80 chromosome 17 open reading frame 80
C7ORF43 chromosome 7 open reading frame 43
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CBX8 chromobox homolog 8
CCNT1 cyclin T1
CDHR2 cadherin-related family member 2
CEP295 centrosomal protein 295kDa
CGREF1 cell growth regulator with EF-hand domain 1
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTNAP3B contactin associated protein-like 3B
CRYBA2 crystallin, beta A2
CXORF56 chromosome X open reading frame 56
DPF3 D4, zinc and double PHD fingers, family 3
ECM1 extracellular matrix protein 1
EN1 engrailed homeobox 1
FAM188A family with sequence similarity 188, member A
FKBP10 FK506 binding protein 10, 65 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GMPR guanosine monophosphate reductase
GPR19 G protein-coupled receptor 19
GPR3 G protein-coupled receptor 3
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HOOK1 hook microtubule-tethering protein 1
HOXC5 homeobox C5
HOXC8 homeobox C8
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL11RA interleukin 11 receptor, alpha
IMPACT impact RWD domain protein
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF2 Kruppel-like factor 2
LMTK1 lemur tail kinase 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC61 leucine rich repeat containing 61
LY86 lymphocyte antigen 86
MAGEF1 melanoma antigen family F1
MAPK12 mitogen-activated protein kinase 12
MECR mitochondrial trans-2-enoyl-CoA reductase
MOCS3 molybdenum cofactor synthesis 3
MUM1 melanoma associated antigen (mutated) 1
MYH15 myosin, heavy chain 15
NARFL nuclear prelamin A recognition factor-like
NHLRC2 NHL repeat containing 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR6 progestin and adipoQ receptor family member VI
PARM1 prostate androgen-regulated mucin-like protein 1
PAX9 paired box 9
PBLD phenazine biosynthesis-like protein domain containing
PHEX phosphate regulating endopeptidase homolog, X-linked
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLL polymerase (DNA directed), lambda
PTPRE protein tyrosine phosphatase, receptor type, E
PWAR5 Prader Willi/Angelman region RNA 5
RAB3A RAB3A, member RAS oncogene family
RANBP17 RAN binding protein 17
RNF25 ring finger protein 25
RWDD2A RWD domain containing 2A
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPEG SPEG complex locus
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
TAGLN transgelin
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
TGFBR3 transforming growth factor, beta receptor III
TMCC2 transmembrane and coiled-coil domain family 2
TSC22D4 TSC22 domain family, member 4
TTLL7 tubulin tyrosine ligase-like family member 7
VEGFB vascular endothelial growth factor B
ZNF214 zinc finger protein 214
ZNF253 zinc finger protein 253
ZNF552 zinc finger protein 552
ZNF675 zinc finger protein 675
ZNF711 zinc finger protein 711
ZSCAN31 zinc finger and SCAN domain containing 31