aminophylline-3036 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the aminophylline-3036 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTA1 actin, alpha 1, skeletal muscle
ADARB1 adenosine deaminase, RNA-specific, B1
ADRA2C adrenoceptor alpha 2C
AGFG1 ArfGAP with FG repeats 1
ALPK3 alpha-kinase 3
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
B3GAT1 beta-1,3-glucuronyltransferase 1
BBS9 Bardet-Biedl syndrome 9
BTNL3 butyrophilin-like 3
C2CD2L C2CD2-like
C8B complement component 8, beta polypeptide
CA5B carbonic anhydrase VB, mitochondrial
CCDC85B coiled-coil domain containing 85B
CCL11 chemokine (C-C motif) ligand 11
CD200 CD200 molecule
CDK19 cyclin-dependent kinase 19
CEP112 centrosomal protein 112kDa
CNTNAP2 contactin associated protein-like 2
CPN2 carboxypeptidase N, polypeptide 2
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF11 DDB1 and CUL4 associated factor 11
DMP1 dentin matrix acidic phosphoprotein 1
DNASE2 deoxyribonuclease II, lysosomal
EGFR epidermal growth factor receptor
EHD2 EH-domain containing 2
EPHA1 EPH receptor A1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXL8 F-box and leucine-rich repeat protein 8
FUBP1 far upstream element (FUSE) binding protein 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GPR35 G protein-coupled receptor 35
GUCA1A guanylate cyclase activator 1A (retina)
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAP1 huntingtin-associated protein 1
HDAC6 histone deacetylase 6
HOXB3 homeobox B3
HOXC10 homeobox C10
HRASLS2 HRAS-like suppressor 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
INHBC inhibin, beta C
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IZUMO4 IZUMO family member 4
KCNK10 potassium channel, two pore domain subfamily K, member 10
KDM4B lysine (K)-specific demethylase 4B
KLF12 Kruppel-like factor 12
LGALS4 lectin, galactoside-binding, soluble, 4
LIG3 ligase III, DNA, ATP-dependent
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LMF1 lipase maturation factor 1
LMTK1 lemur tail kinase 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAPK10 mitogen-activated protein kinase 10
MPPE1 metallophosphoesterase 1
MVD mevalonate (diphospho) decarboxylase
MVP major vault protein
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOX1 NADPH oxidase 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGFR opioid growth factor receptor
PCDH11X protocadherin 11 X-linked
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEX16 peroxisomal biogenesis factor 16
PLD3 phospholipase D family, member 3
PLEKHS1 pleckstrin homology domain containing, family S member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSG1 pregnancy specific beta-1-glycoprotein 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUFY3 RUN and FYVE domain containing 3
SCARB2 scavenger receptor class B, member 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFN stratifin
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPPL2B signal peptide peptidase like 2B
ST7L suppression of tumorigenicity 7 like
STRA6 stimulated by retinoic acid 6
TACR1 tachykinin receptor 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBX5 T-box 5
TECPR2 tectonin beta-propeller repeat containing 2
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNP2 transition protein 2 (during histone to protamine replacement)
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ZNF280B zinc finger protein 280B
ZNF639 zinc finger protein 639
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGB androglobin
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
APOC4 apolipoprotein C-IV
ARG1 arginase 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
BAHD1 bromo adjacent homology domain containing 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF40 chromosome 19 open reading frame 40
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CD3D CD3d molecule, delta (CD3-TCR complex)
CELP carboxyl ester lipase pseudogene
CFAP69 cilia and flagella associated protein 69
CFP complement factor properdin
CHPF chondroitin polymerizing factor
CLCN5 chloride channel, voltage-sensitive 5
COL19A1 collagen, type XIX, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CROT carnitine O-octanoyltransferase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DENND5B DENN/MADD domain containing 5B
DVL1 dishevelled segment polarity protein 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FAM120C family with sequence similarity 120C
FBXL2 F-box and leucine-rich repeat protein 2
FGF23 fibroblast growth factor 23
FNBP1L formin binding protein 1-like
FURIN furin (paired basic amino acid cleaving enzyme)
GJA1 gap junction protein, alpha 1, 43kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1B histone cluster 1, H1b
HIST1H2AI histone cluster 1, H2ai
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
HOXC8 homeobox C8
HYAL2 hyaluronoglucosaminidase 2
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KRT20 keratin 20, type I
KRT81 keratin 81, type II
LOC100286895 cell division cycle 27 homolog pseudogene
LOXL3 lysyl oxidase-like 3
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MAPK3 mitogen-activated protein kinase 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBNL3 muscleblind-like splicing regulator 3
MRPS18C mitochondrial ribosomal protein S18C
MYBPH myosin binding protein H
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCS1 neuronal calcium sensor 1
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NLGN1 neuroligin 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARP11 poly (ADP-ribose) polymerase family, member 11
PBLD phenazine biosynthesis-like protein domain containing
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGP phosphoglycolate phosphatase
PLAT plasminogen activator, tissue
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PMP22 peripheral myelin protein 22
PROCR protein C receptor, endothelial
PRSS21 protease, serine, 21 (testisin)
PTPRS protein tyrosine phosphatase, receptor type, S
RAPSN receptor-associated protein of the synapse
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC17A2 solute carrier family 17, member 2
SMR3B submaxillary gland androgen regulated protein 3B
SPATA2L spermatogenesis associated 2-like
SPINT1 serine peptidase inhibitor, Kunitz type 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM53 transmembrane protein 53
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TUFT1 tuftelin 1
VNN1 vanin 1
ZNF484 zinc finger protein 484
ZNF675 zinc finger protein 675
ZNF76 zinc finger protein 76
ZNF768 zinc finger protein 768