aminophylline-3374 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the aminophylline-3374 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL4 angiopoietin-like 4
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARTN artemin
BTG3 BTG family, member 3
C11ORF16 chromosome 11 open reading frame 16
CCDC71 coiled-coil domain containing 71
CD58 CD58 molecule
CDH8 cadherin 8, type 2
CDHR2 cadherin-related family member 2
CDIP1 cell death-inducing p53 target 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL9A3 collagen, type IX, alpha 3
CPM carboxypeptidase M
CRHR2 corticotropin releasing hormone receptor 2
CTRL chymotrypsin-like
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DLC1 DLC1 Rho GTPase activating protein
EGR3 early growth response 3
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHB6 EPH receptor B6
FAXDC2 fatty acid hydroxylase domain containing 2
FGF21 fibroblast growth factor 21
GABARAPL1 GABA(A) receptor-associated protein like 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GM2A GM2 ganglioside activator
GPER1 G protein-coupled estrogen receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIPK2 homeodomain interacting protein kinase 2
HOXB3 homeobox B3
HP haptoglobin
HSF4 heat shock transcription factor 4
ICOSLG inducible T-cell co-stimulator ligand
IGFALS insulin-like growth factor binding protein, acid labile subunit
INHBE inhibin, beta E
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KREMEN2 kringle containing transmembrane protein 2
LAT2 linker for activation of T cells family, member 2
MEF2C myocyte enhancer factor 2C
MIIP migration and invasion inhibitory protein
MMP11 matrix metallopeptidase 11
MON2 MON2 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MYCNOS MYCN opposite strand
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCR2 natural cytotoxicity triggering receptor 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPY1R neuropeptide Y receptor Y1
NUP50 nucleoporin 50kDa
PAX9 paired box 9
PCDHB12 protocadherin beta 12
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA3 protocadherin gamma subfamily A, 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLEKHO2 pleckstrin homology domain containing, family O member 2
PML promyelocytic leukemia
PRM1 protamine 1
PRMT8 protein arginine methyltransferase 8
PTH2R parathyroid hormone 2 receptor
RAB40C RAB40C, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RDH16 retinol dehydrogenase 16 (all-trans)
REC8 REC8 meiotic recombination protein
RGS14 regulator of G-protein signaling 14
RHAG Rh-associated glycoprotein
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCAND2P SCAN domain containing 2 pseudogene
SCNN1B sodium channel, non voltage gated 1 beta subunit
SELL selectin L
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SIRT5 sirtuin 5
SIX3 SIX homeobox 3
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SORCS3 sortilin-related VPS10 domain containing receptor 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STS steroid sulfatase (microsomal), isozyme S
STYK1 serine/threonine/tyrosine kinase 1
TEX13B testis expressed 13B
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
TLR2 toll-like receptor 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM15 tripartite motif containing 15
TUBB2B tubulin, beta 2B class IIb
USP22 ubiquitin specific peptidase 22
XYLB xylulokinase homolog (H. influenzae)
ZC2HC1C zinc finger, C2HC-type containing 1C

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AHNAK2 AHNAK nucleoprotein 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARPIN actin-related protein 2/3 complex inhibitor
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AUTS2 autism susceptibility candidate 2
BMP15 bone morphogenetic protein 15
C14ORF79 chromosome 14 open reading frame 79
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
C8ORF44 chromosome 8 open reading frame 44
CAPN5 calpain 5
CCNK cyclin K
CIDEB cell death-inducing DFFA-like effector b
CNTNAP1 contactin associated protein 1
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRBN cereblon
CRY2 cryptochrome circadian clock 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNM3 dynamin 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA1 ephrin-A1
EMID1 EMI domain containing 1
FAM184A family with sequence similarity 184, member A
FBXO31 F-box protein 31
FURIN furin (paired basic amino acid cleaving enzyme)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GMPR guanosine monophosphate reductase
GRAMD1C GRAM domain containing 1C
GRTP1 growth hormone regulated TBC protein 1
HCAR3 hydroxycarboxylic acid receptor 3
HDAC7 histone deacetylase 7
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
KRT83 keratin 83, type II
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LIN7A lin-7 homolog A (C. elegans)
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEA3 melanoma antigen family A3
MAST3 microtubule associated serine/threonine kinase 3
MMRN2 multimerin 2
MTCP1 mature T-cell proliferation 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTL5 metallothionein-like 5, testis-specific (tesmin)
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NOTCH1 notch 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PALM paralemmin
PDE12 phosphodiesterase 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
PRAMEF11 PRAME family member 11
PRR14L proline rich 14-like
QPCTL glutaminyl-peptide cyclotransferase-like
RCAN3 RCAN family member 3
RHBG Rh family, B glycoprotein (gene/pseudogene)
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPGR retinitis pigmentosa GTPase regulator
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
RWDD3 RWD domain containing 3
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STIM1 stromal interaction molecule 1
STRN striatin, calmodulin binding protein
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TARP TCR gamma alternate reading frame protein
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TET3 tet methylcytosine dioxygenase 3
TEX40 testis expressed 40
TGFBR3 transforming growth factor, beta receptor III
TLR5 toll-like receptor 5
TMC5 transmembrane channel-like 5
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
UPK2 uroplakin 2
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
ZNF304 zinc finger protein 304
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862