| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the amiodarone-5253 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AAK1 | AP2 associated kinase 1 |
| ADCK4 | aarF domain containing kinase 4 |
| AGBL2 | ATP/GTP binding protein-like 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG10 | autophagy related 10 |
| ATM | ATM serine/threonine kinase |
| ATXN7L1 | ataxin 7-like 1 |
| BGN | biglycan |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CABP2 | calcium binding protein 2 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CD209 | CD209 molecule |
| CD58 | CD58 molecule |
| CDC42 | cell division cycle 42 |
| CDK13 | cyclin-dependent kinase 13 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DCN | decorin |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DENND5B | DENN/MADD domain containing 5B |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMPK | dystrophia myotonica-protein kinase |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| FAM131A | family with sequence similarity 131, member A |
| FAM182B | family with sequence similarity 182, member B |
| FAM214B | family with sequence similarity 214, member B |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FCMR | Fc fragment of IgM receptor |
| FGB | fibrinogen beta chain |
| GLP1R | glucagon-like peptide 1 receptor |
| GOLGA2 | golgin A2 |
| GOLGA8A | golgin A8 family, member A |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HFE | hemochromatosis |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HRASLS2 | HRAS-like suppressor 2 |
| HSPB11 | heat shock protein family B (small), member 11 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IDS | iduronate 2-sulfatase |
| INHBE | inhibin, beta E |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF12 | Kruppel-like factor 12 |
| KLHL24 | kelch-like family member 24 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MST1 | macrophage stimulating 1 |
| MST1L | macrophage stimulating 1-like |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCOR2 | nuclear receptor corepressor 2 |
| NLGN1 | neuroligin 1 |
| NOL12 | nucleolar protein 12 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAPPA2 | pappalysin 2 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PRTN3 | proteinase 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RND2 | Rho family GTPase 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH2D3A | SH2 domain containing 3A |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SYT2 | synaptotagmin II |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLR2 | toll-like receptor 2 |
| TMEM212 | transmembrane protein 212 |
| TREX1 | three prime repair exonuclease 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSC22D2 | TSC22 domain family, member 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF234 | zinc finger protein 234 |
| ZNF696 | zinc finger protein 696 |
| ZNF710 | zinc finger protein 710 |
| ZNF76 | zinc finger protein 76 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTL8 | actin-like 8 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAMTSL3 | ADAMTS-like 3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARSB | arylsulfatase B |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC69 | coiled-coil domain containing 69 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIC | capicua transcriptional repressor |
| CLDN1 | claudin 1 |
| CXXC4 | CXXC finger protein 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DRD1 | dopamine receptor D1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EXOC6B | exocyst complex component 6B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXN2 | forkhead box N2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GAMT | guanidinoacetate N-methyltransferase |
| GAS2 | growth arrest-specific 2 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR19 | G protein-coupled receptor 19 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IQCG | IQ motif containing G |
| ITGA10 | integrin, alpha 10 |
| JMJD4 | jumonji domain containing 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KLK5 | kallikrein-related peptidase 5 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINS | lines homolog (Drosophila) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUC3A | mucin 3A, cell surface associated |
| MYO1E | myosin IE |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARPBP | PARP1 binding protein |
| PDE12 | phosphodiesterase 12 |
| PDE8B | phosphodiesterase 8B |
| PHF14 | PHD finger protein 14 |
| PIPOX | pipecolic acid oxidase |
| PITX2 | paired-like homeodomain 2 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR4 | proline rich 4 (lacrimal) |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RGS2 | regulator of G-protein signaling 2 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SOAT2 | sterol O-acyltransferase 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TESK1 | testis-specific kinase 1 |
| TK1 | thymidine kinase 1, soluble |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| WDR25 | WD repeat domain 25 |
| WDR4 | WD repeat domain 4 |
| YY2 | YY2 transcription factor |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF253 | zinc finger protein 253 |
| ZNF574 | zinc finger protein 574 |
| ZNF750 | zinc finger protein 750 |
| ZNF768 | zinc finger protein 768 |
