| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the amiprilose-3000 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| APOA1 | apolipoprotein A-I |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARTN | artemin |
| ATP13A2 | ATPase type 13A2 |
| ATXN3L | ataxin 3-like |
| AVPR1A | arginine vasopressin receptor 1A |
| BEND5 | BEN domain containing 5 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCDC40 | coiled-coil domain containing 40 |
| CD300C | CD300c molecule |
| CDA | cytidine deaminase |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CEP112 | centrosomal protein 112kDa |
| CYHR1 | cysteine/histidine-rich 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DOPEY2 | dopey family member 2 |
| DPEP2 | dipeptidase 2 |
| DSC3 | desmocollin 3 |
| EDDM3A | epididymal protein 3A |
| EFNA4 | ephrin-A4 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHB1 | EPH receptor B1 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM189A1 | family with sequence similarity 189, member A1 |
| FAM215A | family with sequence similarity 215, member A (non-protein coding) |
| FBN1 | fibrillin 1 |
| FMO5 | flavin containing monooxygenase 5 |
| GLP1R | glucagon-like peptide 1 receptor |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR20 | G protein-coupled receptor 20 |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| ITGB8 | integrin, beta 8 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KLC2 | kinesin light chain 2 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIMD2 | LIM domain containing 2 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MECOM | MDS1 and EVI1 complex locus |
| MED14 | mediator complex subunit 14 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| MYRF | myelin regulatory factor |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCOR2 | nuclear receptor corepressor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NMT1 | N-myristoyltransferase 1 |
| NRG2 | neuregulin 2 |
| NSFL1C | NSFL1 (p97) cofactor (p47) |
| NTN1 | netrin 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAX2 | paired box 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PEG10 | paternally expressed 10 |
| PLCE1 | phospholipase C, epsilon 1 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PODXL2 | podocalyxin-like 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB11B | RAB11B, member RAS oncogene family |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RNF122 | ring finger protein 122 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPL7 | ribosomal protein L7 |
| RS1 | retinoschisin 1 |
| SCIN | scinderin |
| SELL | selectin L |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUSD5 | sushi domain containing 5 |
| TBX5 | T-box 5 |
| TEAD3 | TEA domain family member 3 |
| TEX13A | testis expressed 13A |
| THBD | thrombomodulin |
| TMEM144 | transmembrane protein 144 |
| TMEM242 | transmembrane protein 242 |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| TPM2 | tropomyosin 2 (beta) |
| TUBA4B | tubulin, alpha 4b |
| UNC93A | unc-93 homolog A (C. elegans) |
| VCX2 | variable charge, X-linked 2 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARG1 | arginase 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| CCDC106 | coiled-coil domain containing 106 |
| CDHR2 | cadherin-related family member 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| FAM13C | family with sequence similarity 13, member C |
| FAM53B | family with sequence similarity 53, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHL3 | four and a half LIM domains 3 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GID4 | GID complex subunit 4 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR3 | G protein-coupled receptor 3 |
| GRPR | gastrin-releasing peptide receptor |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H3G | histone cluster 1, H3g |
| HOXA2 | homeobox A2 |
| HOXB9 | homeobox B9 |
| HOXC10 | homeobox C10 |
| HPR | haptoglobin-related protein |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT140 | intraflagellar transport 140 |
| IFT54 | intraflagellar transport 54 |
| JPH3 | junctophilin 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIAA1456 | KIAA1456 |
| LRRC20 | leucine rich repeat containing 20 |
| MAP6D1 | MAP6 domain containing 1 |
| MMP9 | matrix metallopeptidase 9 |
| MRAS | muscle RAS oncogene homolog |
| MTSS1L | metastasis suppressor 1-like |
| NCS1 | neuronal calcium sensor 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OCA2 | oculocutaneous albinism II |
| OCLN | occludin |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PCBP4 | poly(rC) binding protein 4 |
| PCDH12 | protocadherin 12 |
| PDE7B | phosphodiesterase 7B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PLA2G3 | phospholipase A2, group III |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRSS53 | protease, serine, 53 |
| PYGB | phosphorylase, glycogen; brain |
| RAB17 | RAB17, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SCRT1 | scratch family zinc finger 1 |
| SFRP5 | secreted frizzled-related protein 5 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SPATA1 | spermatogenesis associated 1 |
| TCHH | trichohyalin |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TPSB2 | tryptase beta 2 (gene/pseudogene) |
| TRIM36 | tripartite motif containing 36 |
| VEGFB | vascular endothelial growth factor B |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPREB1 | pre-B lymphocyte 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF428 | zinc finger protein 428 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |