| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the amiprilose-4000 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCK2 | aarF domain containing kinase 2 |
| APOM | apolipoprotein M |
| ARG1 | arginase 1 |
| BEND5 | BEN domain containing 5 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD58 | CD58 molecule |
| CDC42 | cell division cycle 42 |
| CEP295 | centrosomal protein 295kDa |
| CRY2 | cryptochrome circadian clock 2 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DTNA | dystrobrevin, alpha |
| EGR1 | early growth response 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| EXOC7 | exocyst complex component 7 |
| FCGBP | Fc fragment of IgG binding protein |
| FUBP1 | far upstream element (FUSE) binding protein 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| IL11 | interleukin 11 |
| IL12A | interleukin 12A |
| IL13 | interleukin 13 |
| IL32 | interleukin 32 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIAA0319L | KIAA0319-like |
| KLF6 | Kruppel-like factor 6 |
| KLHL1 | kelch-like family member 1 |
| KLHL22 | kelch-like family member 22 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LZTS1 | leucine zipper, putative tumor suppressor 1 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MDM4 | MDM4, p53 regulator |
| MED28 | mediator complex subunit 28 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MTMR1 | myotubularin related protein 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYRIP | myosin VIIA and Rab interacting protein |
| NAV3 | neuron navigator 3 |
| NF1 | neurofibromin 1 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NOL10 | nucleolar protein 10 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRKCI | protein kinase C, iota |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RASAL2 | RAS protein activator like 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF39 | ring finger protein 39 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SIRT4 | sirtuin 4 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SMAD4 | SMAD family member 4 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP1 | Sp1 transcription factor |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST7L | suppression of tumorigenicity 7 like |
| SUGP1 | SURP and G patch domain containing 1 |
| SYMPK | symplekin |
| TDRD1 | tudor domain containing 1 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFCP2L1 | transcription factor CP2-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| THBS3 | thrombospondin 3 |
| THOC5 | THO complex 5 |
| TLE2 | transducin-like enhancer of split 2 |
| TMC6 | transmembrane channel-like 6 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSPAN8 | tetraspanin 8 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VCX2 | variable charge, X-linked 2 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF24 | zinc finger protein 24 |
| ZNF440 | zinc finger protein 440 |
| ZNF573 | zinc finger protein 573 |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| AGO4 | argonaute RISC catalytic component 4 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| AXIN1 | axin 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BST1 | bone marrow stromal cell antigen 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CAPN15 | calpain 15 |
| CCDC71 | coiled-coil domain containing 71 |
| CD34 | CD34 molecule |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL9A3 | collagen, type IX, alpha 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EDN1 | endothelin 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EPN1 | epsin 1 |
| FKBP5 | FK506 binding protein 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GPC3 | glypican 3 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC13 | homeobox C13 |
| HOXC8 | homeobox C8 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF13 | Kruppel-like factor 13 |
| KRT33A | keratin 33A, type I |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMTK1 | lemur tail kinase 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC729164 | hCG1732469 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRC15 | leucine rich repeat containing 15 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGP | matrix Gla protein |
| MNMIP1 | manchette microtubule inner protein 1 |
| MON1B | MON1 secretory trafficking family member B |
| MYL5 | myosin, light chain 5, regulatory |
| MYLIP | myosin regulatory light chain interacting protein |
| NAG18 | NAG18 mRNA |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NLGN1 | neuroligin 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAQR5 | progestin and adipoQ receptor family member V |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDE8B | phosphodiesterase 8B |
| PLAC8 | placenta-specific 8 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SLAMF7 | SLAM family member 7 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSTR4 | somatostatin receptor 4 |
| SYNPO | synaptopodin |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VEGFB | vascular endothelial growth factor B |
| VGLL3 | vestigial-like family member 3 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZXDB | zinc finger, X-linked, duplicated B |
