| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the amiprilose-4119 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AFF3 | AF4/FMR2 family, member 3 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ANGPT4 | angiopoietin 4 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| C4BPA | complement component 4 binding protein, alpha |
| C5AR2 | complement component 5a receptor 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CARD10 | caspase recruitment domain family, member 10 |
| CARD14 | caspase recruitment domain family, member 14 |
| CLDN17 | claudin 17 |
| COL5A1 | collagen, type V, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CYTH4 | cytohesin 4 |
| DEPDC5 | DEP domain containing 5 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DMXL2 | Dmx-like 2 |
| DOCK6 | dedicator of cytokinesis 6 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EFCAB11 | EF-hand calcium binding domain 11 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| FAM212B | family with sequence similarity 212, member B |
| GAB1 | GRB2-associated binding protein 1 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GK3P | glycerol kinase 3 pseudogene |
| GPR143 | G protein-coupled receptor 143 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HOXC4 | homeobox C4 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HPX | hemopexin |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ING2 | inhibitor of growth family, member 2 |
| INHBA | inhibin, beta A |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB4 | integrin, beta 4 |
| ITM2C | integral membrane protein 2C |
| KIAA1107 | KIAA1107 |
| LIMD1 | LIM domains containing 1 |
| LOC729164 | hCG1732469 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYL10 | myosin, light chain 10, regulatory |
| MYOZ3 | myozenin 3 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NUP88 | nucleoporin 88kDa |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEK | pleckstrin |
| PODNL1 | podocan-like 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRMT2IP | PRMT2 interacting protein |
| RIF1 | replication timing regulatory factor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF39 | ring finger protein 39 |
| S100A8 | S100 calcium binding protein A8 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SSPN | sarcospan |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TG | thyroglobulin |
| TMOD1 | tropomodulin 1 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNN | tenascin N |
| TOR4A | torsin family 4, member A |
| TP63 | tumor protein p63 |
| TSC22D2 | TSC22 domain family, member 2 |
| USP46 | ubiquitin specific peptidase 46 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZFP64 | ZFP64 zinc finger protein |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF551 | zinc finger protein 551 |
| ZNF639 | zinc finger protein 639 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| AMT | aminomethyltransferase |
| ANKRD28 | ankyrin repeat domain 28 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARRB2 | arrestin, beta 2 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CBX8 | chromobox homolog 8 |
| CCDC69 | coiled-coil domain containing 69 |
| CD83 | CD83 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CEL | carboxyl ester lipase |
| CHST10 | carbohydrate sulfotransferase 10 |
| CRMP1 | collapsin response mediator protein 1 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DVL1 | dishevelled segment polarity protein 1 |
| EN2 | engrailed homeobox 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FMOD | fibromodulin |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GATA4 | GATA binding protein 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H4F | histone cluster 1, H4f |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IL11RA | interleukin 11 receptor, alpha |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLHL25 | kelch-like family member 25 |
| KRT13 | keratin 13, type I |
| KRT83 | keratin 83, type II |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MFAP2 | microfibrillar-associated protein 2 |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRSN2 | neurensin 2 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PORCN | porcupine homolog (Drosophila) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRAMEF11 | PRAME family member 11 |
| PROL1 | proline rich, lacrimal 1 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3D | RAB3D, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPAP1 | RNA polymerase II associated protein 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SDC3 | syndecan 3 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLN | sarcolipin |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNTA1 | syntrophin, alpha 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TBX3 | T-box 3 |
| TCTA | T-cell leukemia translocation altered |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM104 | transmembrane protein 104 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOM1 | target of myb1 (chicken) |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| UPK2 | uroplakin 2 |
| USB1 | U6 snRNA biogenesis 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF10 | zinc finger protein 10 |
| ZNF205 | zinc finger protein 205 |
| ZNF652 | zinc finger protein 652 |
| ZNF747 | zinc finger protein 747 |
