| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the amitriptyline-167 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATF6 | activating transcription factor 6 |
| ATP13A3 | ATPase type 13A3 |
| BBC3 | BCL2 binding component 3 |
| BMP5 | bone morphogenetic protein 5 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK19 | cyclin-dependent kinase 19 |
| CES3 | carboxylesterase 3 |
| CHN2 | chimerin 2 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLEC11A | C-type lectin domain family 11, member A |
| CLSTN2 | calsyntenin 2 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COCH | cochlin |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DRD2 | dopamine receptor D2 |
| DRP2 | dystrophin related protein 2 |
| FCAR | Fc fragment of IgA receptor |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| HBB | hemoglobin, beta |
| HBBP1 | hemoglobin, beta pseudogene 1 |
| HOXB7 | homeobox B7 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) |
| IL2RA | interleukin 2 receptor, alpha |
| IQCK | IQ motif containing K |
| ISCA1 | iron-sulfur cluster assembly 1 |
| IVL | involucrin |
| KLF12 | Kruppel-like factor 12 |
| KRT2 | keratin 2, type II |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LGALS14 | lectin, galactoside-binding, soluble, 14 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LOC647070 | uncharacterized LOC647070 |
| LUZP4 | leucine zipper protein 4 |
| MAP1A | microtubule-associated protein 1A |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTF2 | metal response element binding transcription factor 2 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NEBL | nebulette |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| OCLM | oculomedin |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OPTN | optineurin |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCB | protein kinase C, beta |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| R3HDM1 | R3H domain containing 1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RBL2 | retinoblastoma-like 2 |
| RPS2 | ribosomal protein S2 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| RUNDC3A | RUN domain containing 3A |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCPEP1 | serine carboxypeptidase 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SIK3 | SIK family kinase 3 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLN | sarcolipin |
| SPN | sialophorin |
| ST5 | suppression of tumorigenicity 5 |
| SYNGR1 | synaptogyrin 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TEAD4 | TEA domain family member 4 |
| TMEM115 | transmembrane protein 115 |
| TRIM10 | tripartite motif containing 10 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VRK2 | vaccinia related kinase 2 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AKIRIN1 | akirin 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| AMN | amnion associated transmembrane protein |
| ARRB2 | arrestin, beta 2 |
| ATP11B | ATPase, class VI, type 11B |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CBR3 | carbonyl reductase 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNL2 | cyclin L2 |
| CFD | complement factor D (adipsin) |
| CHEK2 | checkpoint kinase 2 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLDN11 | claudin 11 |
| CLDN15 | claudin 15 |
| CNTFR | ciliary neurotrophic factor receptor |
| COBL | cordon-bleu WH2 repeat protein |
| COMMD9 | COMM domain containing 9 |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CXORF56 | chromosome X open reading frame 56 |
| DCP1A | decapping mRNA 1A |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DYSF | dysferlin |
| ECM1 | extracellular matrix protein 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EPN1 | epsin 1 |
| FAM153A | family with sequence similarity 153, member A |
| FAM198B | family with sequence similarity 198, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FRMD8 | FERM domain containing 8 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLT8D1 | glycosyltransferase 8 domain containing 1 |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| HIRIP3 | HIRA interacting protein 3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| JOSD1 | Josephin domain containing 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLK8 | kallikrein-related peptidase 8 |
| LRRC42 | leucine rich repeat containing 42 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MFAP2 | microfibrillar-associated protein 2 |
| MSX1 | msh homeobox 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PFDN1 | prefoldin subunit 1 |
| PGM3 | phosphoglucomutase 3 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLXNB3 | plexin B3 |
| PP14571 | uncharacterized LOC100130449 |
| PQLC2 | PQ loop repeat containing 2 |
| QDPR | quinoid dihydropteridine reductase |
| RAB4B | RAB4B, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RLBP1 | retinaldehyde binding protein 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SNX6 | sorting nexin 6 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| USB1 | U6 snRNA biogenesis 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR7 | WD repeat domain 7 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF394 | zinc finger protein 394 |
| ZNF586 | zinc finger protein 586 |
