| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the amitriptyline-1701 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACRV1 | acrosomal vesicle protein 1 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APOC1 | apolipoprotein C-I |
| APOE | apolipoprotein E |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AUTS2 | autism susceptibility candidate 2 |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C3 | complement component 3 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
| CD44 | CD44 molecule (Indian blood group) |
| CD83 | CD83 molecule |
| CEP41 | centrosomal protein 41kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| COMT | catechol-O-methyltransferase |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EEA1 | early endosome antigen 1 |
| EPHA2 | EPH receptor A2 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FADS3 | fatty acid desaturase 3 |
| FLOT1 | flotillin 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GAN | gigaxonin |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GPR137 | G protein-coupled receptor 137 |
| GRPR | gastrin-releasing peptide receptor |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INSIG1 | insulin induced gene 1 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| JRK | Jrk homolog (mouse) |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMAN1 | lectin, mannose-binding, 1 |
| LPIN1 | lipin 1 |
| MAP4 | microtubule-associated protein 4 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCOLN3 | mucolipin 3 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYO1F | myosin IF |
| NF1 | neurofibromin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NTF3 | neurotrophin 3 |
| PCDHB13 | protocadherin beta 13 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2G10 | phospholipase A2, group X |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMP22 | peripheral myelin protein 22 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTRF | polymerase I and transcript release factor |
| RAB28 | RAB28, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANBP3 | RAN binding protein 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| SCAMP1 | secretory carrier membrane protein 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SFXN3 | sideroflexin 3 |
| SIK1 | salt-inducible kinase 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLN | sarcolipin |
| SMAD3 | SMAD family member 3 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SQLE | squalene epoxidase |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STAT4 | signal transducer and activator of transcription 4 |
| STK16 | serine/threonine kinase 16 |
| TBC1D5 | TBC1 domain family, member 5 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMCO6 | transmembrane and coiled-coil domains 6 |
| TMEM63A | transmembrane protein 63A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM2 | tripartite motif containing 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UST | uronyl-2-sulfotransferase |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF814 | zinc finger protein 814 |
| Symbol | Name |
|---|---|
| AHR | aryl hydrocarbon receptor |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARRB2 | arrestin, beta 2 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL2L2 | BCL2-like 2 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN15 | calpain 15 |
| CCNT1 | cyclin T1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DEAF1 | DEAF1 transcription factor |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EBNA1BP2 | EBNA1 binding protein 2 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFHD1 | EF-hand domain family, member D1 |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBP5 | FK506 binding protein 5 |
| FKBPL | FK506 binding protein like |
| FZD4 | frizzled class receptor 4 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HIRA | histone cell cycle regulator |
| HIST1H2AE | histone cluster 1, H2ae |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IPO8 | importin 8 |
| IRX4 | iroquois homeobox 4 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF16B | kinesin family member 16B |
| KRT86 | keratin 86, type II |
| LAMB3 | laminin, beta 3 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC100272216 | uncharacterized LOC100272216 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC14 | leucine rich repeat containing 14 |
| LRRC61 | leucine rich repeat containing 61 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED15 | mediator complex subunit 15 |
| MGC12488 | |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MYO1D | myosin ID |
| NDE1 | nudE neurodevelopment protein 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NRSN2 | neurensin 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PADI1 | peptidyl arginine deiminase, type I |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PMEL | premelanosome protein |
| PRAF2 | PRA1 domain family, member 2 |
| PROS1 | protein S (alpha) |
| PTK6 | protein tyrosine kinase 6 |
| RNF122 | ring finger protein 122 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SNHG20 | small nucleolar RNA host gene 20 |
| SNX10 | sorting nexin 10 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPIDR | scaffolding protein involved in DNA repair |
| STBD1 | starch binding domain 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TDRD1 | tudor domain containing 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM159 | transmembrane protein 159 |
| TMEM62 | transmembrane protein 62 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM25 | tripartite motif containing 25 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TUBA3D | tubulin, alpha 3d |
| UNC119 | unc-119 homolog (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZFAND3 | zinc finger, AN1-type domain 3 |
| ZNF107 | zinc finger protein 107 |
| ZNF492 | zinc finger protein 492 |
| ZNF665 | zinc finger protein 665 |
