| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the amitriptyline-1823 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHI1 | Abelson helper integration site 1 |
| AMOTL2 | angiomotin like 2 |
| ANGPTL4 | angiopoietin-like 4 |
| ANKRD12 | ankyrin repeat domain 12 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BAX | BCL2-associated X protein |
| BCL6 | B-cell CLL/lymphoma 6 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CEP68 | centrosomal protein 68kDa |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| EPHB2 | EPH receptor B2 |
| FAM129A | family with sequence similarity 129, member A |
| FAM174B | family with sequence similarity 174, member B |
| FCF1 | FCF1 rRNA-processing protein |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H3G | histone cluster 1, H3g |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ICK | intestinal cell (MAK-like) kinase |
| IFI16 | interferon, gamma-inducible protein 16 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL6 | interleukin 6 |
| IRS2 | insulin receptor substrate 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLK10 | kallikrein-related peptidase 10 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| MAGEH1 | melanoma antigen family H1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED28 | mediator complex subunit 28 |
| MEX3D | mex-3 RNA binding family member D |
| MT1F | metallothionein 1F |
| NCOA3 | nuclear receptor coactivator 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NID2 | nidogen 2 (osteonidogen) |
| PCDH1 | protocadherin 1 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PIDD1 | p53-induced death domain protein 1 |
| PKP2 | plakophilin 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PRKCH | protein kinase C, eta |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PTX3 | pentraxin 3, long |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RARS | arginyl-tRNA synthetase |
| RBL2 | retinoblastoma-like 2 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RGS10 | regulator of G-protein signaling 10 |
| S100A3 | S100 calcium binding protein A3 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SQLE | squalene epoxidase |
| STC2 | stanniocalcin 2 |
| STK10 | serine/threonine kinase 10 |
| STXBP3 | syntaxin binding protein 3 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMEM156 | transmembrane protein 156 |
| TMEM184C | transmembrane protein 184C |
| TMEM50B | transmembrane protein 50B |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIB3 | tribbles pseudokinase 3 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VAMP4 | vesicle-associated membrane protein 4 |
| WBP4 | WW domain binding protein 4 |
| WDR62 | WD repeat domain 62 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF804A | zinc finger protein 804A |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC6 | armadillo repeat containing 6 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASZ1 | castor zinc finger 1 |
| CENPT | centromere protein T |
| CFD | complement factor D (adipsin) |
| CNTNAP1 | contactin associated protein 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CST4 | cystatin S |
| CXORF56 | chromosome X open reading frame 56 |
| DCLRE1A | DNA cross-link repair 1A |
| DCLRE1B | DNA cross-link repair 1B |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EFNA3 | ephrin-A3 |
| EFNB1 | ephrin-B1 |
| EN2 | engrailed homeobox 2 |
| EXO1 | exonuclease 1 |
| FAM53B | family with sequence similarity 53, member B |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FKBPL | FK506 binding protein like |
| GALT | galactose-1-phosphate uridylyltransferase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC7 | histone deacetylase 7 |
| HIST1H3B | histone cluster 1, H3b |
| HOXC4 | homeobox C4 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMC3 | laminin, gamma 3 |
| LOC100272216 | uncharacterized LOC100272216 |
| MEIS1 | Meis homeobox 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MTMR12 | myotubularin related protein 12 |
| MYL5 | myosin, light chain 5, regulatory |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUBP1 | nucleotide binding protein 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFML2A | olfactomedin-like 2A |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PLD3 | phospholipase D family, member 3 |
| POLH | polymerase (DNA directed), eta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RNF2 | ring finger protein 2 |
| RNF25 | ring finger protein 25 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRP1 | ribosomal RNA processing 1 |
| SDC3 | syndecan 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SIX1 | SIX homeobox 1 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| STAC | SH3 and cysteine rich domain |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TBX19 | T-box 19 |
| TGFB3 | transforming growth factor, beta 3 |
| THOC6 | THO complex 6 |
| TLN1 | talin 1 |
| TMEM40 | transmembrane protein 40 |
| TOM1 | target of myb1 (chicken) |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YEATS4 | YEATS domain containing 4 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF350 | zinc finger protein 350 |
| ZNF385D | zinc finger protein 385D |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
| ZNF839 | zinc finger protein 839 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
