| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the amitriptyline-1865 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALS2CL | ALS2 C-terminal like |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOE | apolipoprotein E |
| APP | amyloid beta (A4) precursor protein |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATF6B | activating transcription factor 6 beta |
| ATG10 | autophagy related 10 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRD4 | bromodomain containing 4 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CD70 | CD70 molecule |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CREM | cAMP responsive element modulator |
| CTSV | cathepsin V |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DEAF1 | DEAF1 transcription factor |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETV4 | ets variant 4 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM214B | family with sequence similarity 214, member B |
| GAA | glucosidase, alpha; acid |
| GIMAP5 | GTPase, IMAP family member 5 |
| GLTP | glycolipid transfer protein |
| GPR27 | G protein-coupled receptor 27 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| ICAM2 | intercellular adhesion molecule 2 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IGHM | immunoglobulin heavy constant mu |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JUN | jun proto-oncogene |
| JUP | junction plakoglobin |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KDM4A | lysine (K)-specific demethylase 4A |
| KLF6 | Kruppel-like factor 6 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP4 | microtubule-associated protein 4 |
| MICA | MHC class I polypeptide-related sequence A |
| MIIP | migration and invasion inhibitory protein |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PEG3 | paternally expressed 3 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PEX5 | peroxisomal biogenesis factor 5 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHACTR1 | phosphatase and actin regulator 1 |
| PLA2G15 | phospholipase A2, group XV |
| PLK4 | polo-like kinase 4 |
| PLXNA1 | plexin A1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RB1 | retinoblastoma 1 |
| RPA4 | replication protein A4, 30kDa |
| RREB1 | ras responsive element binding protein 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD5 | SMAD family member 5 |
| SORT1 | sortilin 1 |
| SPN | sialophorin |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STK16 | serine/threonine kinase 16 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TEX261 | testis expressed 261 |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TMEM184C | transmembrane protein 184C |
| UBOX5 | U-box domain containing 5 |
| UTRN | utrophin |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF324 | zinc finger protein 324 |
| ZNF345 | zinc finger protein 345 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACOT8 | acyl-CoA thioesterase 8 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD52 | CD52 molecule |
| CD82 | CD82 molecule |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CPTP | ceramide-1-phosphate transfer protein |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| FKBPL | FK506 binding protein like |
| FLCN | folliculin |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H2BI | histone cluster 1, H2bi |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT88 | intraflagellar transport 88 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA0319L | KIAA0319-like |
| KIAA0894 | KIAA0894 protein |
| LARS | leucyl-tRNA synthetase |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAGEF1 | melanoma antigen family F1 |
| MBTD1 | mbt domain containing 1 |
| METTL2B | methyltransferase like 2B |
| METTL8 | methyltransferase like 8 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MYO5C | myosin VC |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PIR | pirin (iron-binding nuclear protein) |
| PITRM1 | pitrilysin metallopeptidase 1 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POLH | polymerase (DNA directed), eta |
| PRKCZ | protein kinase C, zeta |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SETD1A | SET domain containing 1A |
| SH2D3C | SH2 domain containing 3C |
| SIK1 | salt-inducible kinase 1 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPAG1 | sperm associated antigen 1 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM159 | transmembrane protein 159 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TTPAL | tocopherol (alpha) transfer protein-like |
| UNKL | unkempt family zinc finger-like |
| WT1-AS | WT1 antisense RNA |
| WWC2 | WW and C2 domain containing 2 |
| XAB2 | XPA binding protein 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF264 | zinc finger protein 264 |
| ZNF426 | zinc finger protein 426 |
| ZNF551 | zinc finger protein 551 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF768 | zinc finger protein 768 |
| ZNF91 | zinc finger protein 91 |
