| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the amitriptyline-5453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADORA1 | adenosine A1 receptor |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPT4 | angiopoietin 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATF3 | activating transcription factor 3 |
| ATXN2L | ataxin 2-like |
| B9D1 | B9 protein domain 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BAIAP2 | BAI1-associated protein 2 |
| BIN1 | bridging integrator 1 |
| C3 | complement component 3 |
| CADM3 | cell adhesion molecule 3 |
| CCNJL | cyclin J-like |
| CFP | complement factor properdin |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DUSP13 | dual specificity phosphatase 13 |
| EGR1 | early growth response 1 |
| EPHA1 | EPH receptor A1 |
| ETV5 | ets variant 5 |
| FAM63B | family with sequence similarity 63, member B |
| FANCA | Fanconi anemia, complementation group A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXI1 | forkhead box I1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) |
| GPR25 | G protein-coupled receptor 25 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUCY2D | guanylate cyclase 2D, membrane (retina-specific) |
| HIST1H3A | histone cluster 1, H3a |
| HMG20B | high mobility group 20B |
| HOXA10 | homeobox A10 |
| HOXA9 | homeobox A9 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL24 | interleukin 24 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIAA1462 | KIAA1462 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF13 | Kruppel-like factor 13 |
| KLF2 | Kruppel-like factor 2 |
| KXD1 | KxDL motif containing 1 |
| LAPTM5 | lysosomal protein transmembrane 5 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4 | microtubule-associated protein 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL16 | methyltransferase like 16 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MORN1 | MORN repeat containing 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEB | nebulin |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OPRK1 | opioid receptor, kappa 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A11 | S100 calcium binding protein A11 |
| S100A7 | S100 calcium binding protein A7 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC22A6 | solute carrier family 22 (organic anion transporter), member 6 |
| SLC35E2 | solute carrier family 35, member E2 |
| SNTA1 | syntrophin, alpha 1 |
| SSTR4 | somatostatin receptor 4 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYT13 | synaptotagmin XIII |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D22A | TBC1 domain family, member 22A |
| TLR2 | toll-like receptor 2 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPH1 | tryptophan hydroxylase 1 |
| TRIM2 | tripartite motif containing 2 |
| UBXN1 | UBX domain protein 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CCNO | cyclin O |
| CD82 | CD82 molecule |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFD | complement factor D (adipsin) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DBF4B | DBF4 zinc finger B |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DOCK1 | dedicator of cytokinesis 1 |
| DVL1 | dishevelled segment polarity protein 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FAAH | fatty acid amide hydrolase |
| FAM155B | family with sequence similarity 155, member B |
| FGL1 | fibrinogen-like 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLCN | folliculin |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GRAMD4 | GRAM domain containing 4 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4A | histone cluster 1, H4a |
| ICK | intestinal cell (MAK-like) kinase |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| JRKL | JRK-like |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LHX6 | LIM homeobox 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOL10 | nucleolar protein 10 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| PC | pyruvate carboxylase |
| PCDHB13 | protocadherin beta 13 |
| PER3 | period circadian clock 3 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PITX2 | paired-like homeodomain 2 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PODNL1 | podocan-like 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF39 | ring finger protein 39 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIRT6 | sirtuin 6 |
| SKI | SKI proto-oncogene |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPON2 | spondin 2, extracellular matrix protein |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TESC | tescalcin |
| TET3 | tet methylcytosine dioxygenase 3 |
| TLN1 | talin 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM57 | transmembrane protein 57 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM36 | tripartite motif containing 36 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TTBK2 | tau tubulin kinase 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| VGF | VGF nerve growth factor inducible |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF280D | zinc finger protein 280D |
| ZNF430 | zinc finger protein 430 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF804A | zinc finger protein 804A |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
