| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the amodiaquine-1570 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACVRL1 | activin A receptor type II-like 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| ARSB | arylsulfatase B |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ELAC2 | elaC ribonuclease Z 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HCFC1 | host cell factor C1 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4J | histone cluster 1, H4j |
| HOXA10 | homeobox A10 |
| HOXC11 | homeobox C11 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ISCA1 | iron-sulfur cluster assembly 1 |
| JRK | Jrk homolog (mouse) |
| KIF20B | kinesin family member 20B |
| KIZ | kizuna centrosomal protein |
| KLHL18 | kelch-like family member 18 |
| KLHL3 | kelch-like family member 3 |
| LMTK1 | lemur tail kinase 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MED7 | mediator complex subunit 7 |
| METTL4 | methyltransferase like 4 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MPZ | myelin protein zero |
| NADK | NAD kinase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCBP2 | poly(rC) binding protein 2 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLS1 | plastin 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PREP | prolyl endopeptidase |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTAFR | platelet-activating factor receptor |
| PTMA | prothymosin, alpha |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RPS14P3 | ribosomal protein S14 pseudogene 3 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SMAD3 | SMAD family member 3 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 |
| SON | SON DNA binding protein |
| SORBS3 | sorbin and SH3 domain containing 3 |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| STK19 | serine/threonine kinase 19 |
| TCTN2 | tectonic family member 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TTN | titin |
| TULP3 | tubby like protein 3 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| YY2 | YY2 transcription factor |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF154 | zinc finger protein 154 |
| ZNF277 | zinc finger protein 277 |
| ZNF614 | zinc finger protein 614 |
| ZNF783 | zinc finger family member 783 |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| ACOT9 | acyl-CoA thioesterase 9 |
| AES | amino-terminal enhancer of split |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| AMT | aminomethyltransferase |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATXN2 | ataxin 2 |
| BEX1 | brain expressed, X-linked 1 |
| BIN2 | bridging integrator 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C19ORF24 | chromosome 19 open reading frame 24 |
| CCDC47 | coiled-coil domain containing 47 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CENPC | centromere protein C |
| CENPJ | centromere protein J |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DYSF | dysferlin |
| ECD | ecdysoneless homolog (Drosophila) |
| ERO1L | ERO1-like (S. cerevisiae) |
| FADS2 | fatty acid desaturase 2 |
| FAM179B | family with sequence similarity 179, member B |
| FASTKD5 | FAST kinase domains 5 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FPGS | folylpolyglutamate synthase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GRPR | gastrin-releasing peptide receptor |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL4R | interleukin 4 receptor |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IPO13 | importin 13 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITM2C | integral membrane protein 2C |
| JOSD1 | Josephin domain containing 1 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCRS1 | microspherule protein 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MIS18BP1 | MIS18 binding protein 1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MUTYH | mutY homolog |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 |
| NINJ1 | ninjurin 1 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OPHN1 | oligophrenin 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PARP1 | poly (ADP-ribose) polymerase 1 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PMM1 | phosphomannomutase 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRPF38B | pre-mRNA processing factor 38B |
| PTGES2 | prostaglandin E synthase 2 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RPE | ribulose-5-phosphate-3-epimerase |
| SALL2 | spalt-like transcription factor 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLN | sarcolipin |
| SNX6 | sorting nexin 6 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| STRA13 | stimulated by retinoic acid 13 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) |
| TERT | telomerase reverse transcriptase |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSEN34 | TSEN34 tRNA splicing endonuclease subunit |
| TSPAN32 | tetraspanin 32 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTC13 | tetratricopeptide repeat domain 13 |
| TULP4 | tubby like protein 4 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| USP21 | ubiquitin specific peptidase 21 |
| WDR82 | WD repeat domain 82 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF140 | zinc finger protein 140 |
| ZNF175 | zinc finger protein 175 |
| ZNF212 | zinc finger protein 212 |
| ZNF426 | zinc finger protein 426 |
