| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the amodiaquine-3186 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ACRV1 | acrosomal vesicle protein 1 |
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I |
| AKAP6 | A kinase (PRKA) anchor protein 6 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARMC4 | armadillo repeat containing 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATXN3 | ataxin 3 |
| BGN | biglycan |
| BIN2 | bridging integrator 2 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCNJL | cyclin J-like |
| CD52 | CD52 molecule |
| CEP41 | centrosomal protein 41kDa |
| CES1 | carboxylesterase 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPQ | carboxypeptidase Q |
| CTSE | cathepsin E |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMPK | dystrophia myotonica-protein kinase |
| EBF2 | early B-cell factor 2 |
| ECE1 | endothelin converting enzyme 1 |
| EDNRB | endothelin receptor type B |
| EGR2 | early growth response 2 |
| EMILIN1 | elastin microfibril interfacer 1 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPYC | epiphycan |
| ESRRG | estrogen-related receptor gamma |
| FLNC | filamin C, gamma |
| FNDC8 | fibronectin type III domain containing 8 |
| FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| GLRA3 | glycine receptor, alpha 3 |
| HFE | hemochromatosis |
| HIST1H2BO | histone cluster 1, H2bo |
| IGHM | immunoglobulin heavy constant mu |
| IQCC | IQ motif containing C |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA0040 | KIAA0040 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT85 | keratin 85, type II |
| KRT9 | keratin 9, type I |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LOC644450 | uncharacterized LOC644450 |
| LST1 | leukocyte specific transcript 1 |
| LY9 | lymphocyte antigen 9 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MSR1 | macrophage scavenger receptor 1 |
| MYEF2 | myelin expression factor 2 |
| MYO7A | myosin VIIA |
| N4BP3 | NEDD4 binding protein 3 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NUP214 | nucleoporin 214kDa |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIPOX | pipecolic acid oxidase |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PTRF | polymerase I and transcript release factor |
| RAB3B | RAB3B, member RAS oncogene family |
| RASL12 | RAS-like, family 12 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SAPCD1 | suppressor APC domain containing 1 |
| SDC2 | syndecan 2 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E |
| SFTPD | surfactant protein D |
| SHOX2 | short stature homeobox 2 |
| SLAMF7 | SLAM family member 7 |
| SLAMF8 | SLAM family member 8 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 |
| SMG7-AS1 | SMG7 antisense RNA 1 |
| SORT1 | sortilin 1 |
| SPRR1B | small proline-rich protein 1B |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STAMBPL1 | STAM binding protein-like 1 |
| STAT5A | signal transducer and activator of transcription 5A |
| STK24 | serine/threonine kinase 24 |
| THBD | thrombomodulin |
| TMEM242 | transmembrane protein 242 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRAPPC9 | trafficking protein particle complex 9 |
| TRBC1 | T cell receptor beta constant 1 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TUBB2B | tubulin, beta 2B class IIb |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALPK1 | alpha-kinase 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APOD | apolipoprotein D |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BCL7C | B-cell CLL/lymphoma 7C |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMKV | CaM kinase-like vesicle-associated |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD302 | CD302 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DEAF1 | DEAF1 transcription factor |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSE | dermatan sulfate epimerase |
| EFNA3 | ephrin-A3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM188A | family with sequence similarity 188, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO22 | F-box protein 22 |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FMO4 | flavin containing monooxygenase 4 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GAMT | guanidinoacetate N-methyltransferase |
| GMPR | guanosine monophosphate reductase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC4 | glypican 4 |
| HIST1H2AL | histone cluster 1, H2al |
| HOOK1 | hook microtubule-tethering protein 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL15RA | interleukin 15 receptor, alpha |
| INCENP | inner centromere protein antigens 135/155kDa |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| KLF2 | Kruppel-like factor 2 |
| KRT13 | keratin 13, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC257152 | uncharacterized LOC257152 |
| LOC729164 | hCG1732469 |
| LPXN | leupaxin |
| LRRC49 | leucine rich repeat containing 49 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MDM4 | MDM4, p53 regulator |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP9 | matrix metallopeptidase 9 |
| MXD3 | MAX dimerization protein 3 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEK11 | NIMA-related kinase 11 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| ONECUT2 | one cut homeobox 2 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDHA6 | protocadherin alpha 6 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PRR4 | proline rich 4 (lacrimal) |
| PTDSS2 | phosphatidylserine synthase 2 |
| RANGRF | RAN guanine nucleotide release factor |
| RNF39 | ring finger protein 39 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| TCP10 | t-complex 10 |
| TMEM120B | transmembrane protein 120B |
| TMEM183A | transmembrane protein 183A |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRIM45 | tripartite motif containing 45 |
| UNC119 | unc-119 homolog (C. elegans) |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF266 | zinc finger protein 266 |
| ZNF324 | zinc finger protein 324 |
| ZNF34 | zinc finger protein 34 |
| ZNF668 | zinc finger protein 668 |
| ZNF701 | zinc finger protein 701 |
